Unit 5: Cell Division And Signaling Flashcards

1
Q

3 stages of cell signaling

A
  • Signal(ligand attaches to receptor to deliver the signal)
  • transduction(signal is translated)
  • Response(cellular response occurs)
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2
Q

Kinetichore

A

Proteins within the centromere that the spindle fibers attach to

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3
Q

Meiosis

A

Creates 4 genetically different sex cells

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4
Q

Transduction

A

Converting signals to a form that can bring cellular action

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5
Q

Interphase

A
  • G1, S, G2

- 90% of a cells life

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6
Q

Prophase

A

DNA becomes visible

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7
Q

Prometaphase

A

Nuclear envelope disappears and chromosomes start to line up in the middle

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8
Q

Metaphase

A

Spindle fibers pull the chromosomes to the center of the cell

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9
Q

Anaphase

A

Spindle fibers pull the sister chromatids to opposite sides of the cell

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10
Q

Telophase/cytokinesis

A

The cytosol splits in two and the membrane is pinched

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11
Q

End product of mitosis

A

Two identical daughter cells

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12
Q

How does meiosis contribute to genetic diversity

A

It creates genetically different cells

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13
Q

What happens during phosphorylation cascade

A

You are adding a phosphate to activate an enzyme

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14
Q

What happens in G1

A

Normal cell things

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15
Q

What happens in S phase

A

DNA replicates

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16
Q

What happens in G2

A

Cell grows and prepares to divide

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17
Q

What does 2^n mean

A

How to determine the number of possibilities for genetic variation
Ex humans. 2^23

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18
Q

What is crossing over

A
  • Occurs in meiosis
  • helps create genetic diversity
  • where two chromosomes touch and swap DNA
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19
Q

What is a protein kinase

A

A protein that adds a phosphate

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20
Q

What is cancer

A

Cells that grow uncontrollably and take resources from surrounding cells

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21
Q

Diploid cells

A
  • 2n

- have two versions of each chromosome(pair from both parents)

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22
Q

Mitosis checkpoints

A
  • G1, G2, M

- make sure the cell does not divide unnecessarily or incorrectly

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23
Q

G protein coupled receptor

A

A signal protein(ligand) bonds with the receptor causing a GDP to come to the receptor. When this happens the GDP is activated. The GDP then travels to activate and enzyme which will then allow cellular response to occur.

24
Q

Product of meiosis

A

4 genetically different haploid cells

25
Law of independent assortment
Chromosomes can line up in different order to produce genetic diversity(chromosomes from mom and dad can line up on either the left or right side of the cell during metaphase 1)
26
Metaphase 1
Chromosome pairs(one from mom one from dad) line up in the middle of the cell)
27
Anaphase 1
Chromosome pairs are pulled apart
28
Telophase 1/Cytokinesis 1
Cell is split into 2
29
Metaphase 2
Chromosomes line up in the center of the cell
30
Anaphase 2
Sister chromatids are pulled apart
31
Telophase 2/Cytokinesis 2
Cell is split to create gametes
32
What type of cell is produce after meiosis 1
Duplicated haploid cells
33
Haploid cells
- n - you havE one version of each chromosome - half the amount of the diploid number of cells
34
Sister chromatids
Two versions of the same duplicated chromosome
35
Homologous chromosomes
Chromosome pairs (chromosomes from mom and dad that are alike)
36
Steps of Tyrosine kinase
Two receptors that when the ligand attaches come together(dimer). The tyrosines on the bottom of the receptor are activated through gaining a phosphate. This process can activate more than one enzyme
37
What must the signaling molecule fit into to deliver the message
The receptor
38
What is a ligand
A signaling molecule
39
What are the second messengers for cell signaling
Non protein molecules/ions
40
What is the benefit of the phosphorylation cascade
Enhance or amplify the reaction
41
Ion gated ligand channel
Ligand bond to the receptor causing it to open or close allowing ions to move
42
What are neurotransmitters
Ligands
43
What causes a cell signal to stop
The ligand detaches
44
Centrisome
Where spindle fibers come from
45
G1 checkpoint
Should the cell divide and does it have the resources to
46
G2 checkpoint
Did the DNA replicate properly
47
What regulates the G2 checkpoint
Cyclin and CDK
48
M checkpoint
- During metaphase | - makes sure all the spindle fibers are attached
49
Crossing over
- Happens in prophase 1 | - chromosomes swap DNA
50
How many chromosomes are in somatic cells
46
51
Examples of asexual reproduction
Binary fission
52
How many chromosomes in sex cells
23
53
What are spindle fibers made of
Microtubules
54
What do spindle fibers do
They maneuver chromosomes and pull them apart
55
What makes tyrosine kinase unique
It has 2 receptors and can activated to 6 enzymes
56
What do g protein receptors and tyrosine kinase have in common
They both use phosphates