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Flashcards in V - Special Topics Deck (80)
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1

Regulation of body temperature is mediated by the

hypothalamus

2

Detected T in the _____ is compared with the _____ T in the hypothalamus.

Skin - detected T, hypothalamus - set-point T

3

Mechanisms activated when detected T is < set-point T

Heat Generating

4

Mechanisms activated when detected T is > set-point T

Heat Loss

5

Temperature Regulation: Shivering, thyroid hormone production, piloerection, skin vasoconstriction (alpha-1), brown fat in babies (beta-3)

Heat Generating

6

Temperature Regulation: Sweating, skin vasodilation

Heat Loss

7

Temperature Regulation: Insulator

Fat

8

Temperature Regulation: Radiator System

Skin: cold - vasoconstriction, hot - vasodilation

9

Most of the body heat is lost in what way?

radiation > evaporation > conduction to air > conduction to objects

10

Pathophysiology of Fever

pyrogens → increased IL-1 (α & β), IL-6 → increased prostaglandins (PG-E2) → increased set-point T in the hypotalamus

11

Excessive sweating causing fainting

Heat Exhaustion

12

HIgh T causing tissue damage and impaired responses

Heat Stroke

13

High T secondary to use of succinylcholine and halothane

Malignant Hyperthermia - defective Ca channels (Ryanodine) in sarcoplasmic reticulum → hyperexcitable muscles, Tx: Dantrolene - muscle relaxant

14

Malignant hyperthermia is caused by _____ & _____.

succinylcholine, halothane

15

Malignant hyperthermia is treated with

Dantrolene - muscle relaxant

16

Energy Systems: Cell ATP,cell phosphocreatine

Phosphagen Energy System

17

Energy Systems: First 8-10 seconds

Phosphagen Energy System

18

Energy Systems: 100m dash, jumping, diving

Phosphagen Energy System

19

Energy Systems: Anaerobic, reconstitutes ATP and phosphocreatine

Glycogen-Lactic Acid System

20

Energy Systems: 1.3-1.6 minutes

Glycogen-Lactic Acid System

21

Energy Systems: Tennis, soccer

Glycogen-Lactic Acid System

22

Energy Systems: Aerobic, reconstitutes ATP and phosphocreatine, glycogen-lactice acid cycle

Aerobic System

23

Energy Systems: Unlimited as long as there's energy supply

Aerobic System

24

Energy Systems: Long-distance marathon

Aerobic System

25

Energy Systems: Fats provide

50% of the energy needed after 3-4 hours

26

Basis for muscle endurance

Glycogen: 400g - muscle, 100g - liver

27

Best diet for muscle glycogen recovery

Carbo-Loading for 2 days

28

Increased muscle strength is due to

increased muscle mass

29

Exercise: Maximal breathing capacity

150-170L/min

30

Exercise: Pulmonary ventilation during maximal exercise

100-110L/min