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Flashcards in vaccines 1&2 Deck (57)
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1

Enhance a specific immune response in an animal by exposing it to
vaccination

immunoprophylaxis

2

provides immediate protection, works for agents that are poor immunogens or where there are no vaccinations

passive immunoprophylaxis

3

which is strong/longer protection? active or passive immunoprophylaxis

active

4

indicates a successful induction of an immune response

immunization

5

T/F
all vaccines provide immunization

false

6

administration of an antigenic product

vaccination

7

____ is important for persistent intracellular or latent infection

cell mediated immunity

8

where do live vaccines replicate

in the host

9

which route of administration gives the greatest systemic immune response

subcutaneous

10

this route of administration stimulates a local IgA immune response

intranasal

11

T/F
killed vaccines replicate in the host

false they do not

12

T/F
non-infectious killed vaccines are stable and do not pose a risk to getting sick

TRUE

13

T/F
The immune response to killed vaccines is generally a shorter duration and narrower spectrum

true

14

purified subunit vaccines

Contain an immunogenic component of an infectious agent

15

In vitro production of large quantities of immunogenic proteins through genetic engineering specific antigens into bacteria, yeasts or cell lines

genetically engineered subunit protein vaccine

16

two reasons adjuvants are added

to increase
• Immunostimulation
• Duration of immunity

17

how do adjuvants work

• Prolong antigen exposure
• Enhance antigen presentation
• Increase cytokine and immune response

18

T/F
Adjuvants have been implicated as causing granulomatous reactions at vaccine sites

TRUE -- sarcomas in cats with FeLV using aluminum

19

what vaccines currently have transdermal use

Current used in FeLV in cats and canine melanoma vaccine

20

mucosal application vaccines

Currently used in Canine and feline respiratory infections (intranasal), FeCoV

21

Vaccines for kittens and puppies end at ??

16 weeks of age -- boosters given at 6 months to a year after completion

22

T/F
vaccines protect 100% of the population

FALSE

23

immediate hypersensitivity reaction

type 1

24

involves IgE mediated release of histamine

hypersensitivity type 1

25

which hypersensitivity reaction causes Angioedema and allergic rhinoconjunctivitis

type 1

26

Involves IgG or IgM antibodies bound to cell surface antigens with subsequent complement fixation

hypersensitivity type 2

27

which hypersensitivity reaction causes host cell hemolysis leading to hemolytic anemia

cytotoxic hypersensitivity reaction

28

what hypersensitivity reaction might inactivated rabies vaccine cause

type 1

29

The MLV of parvovirus could potentially cause this hypersensitivity reaction

type 2 - cytotoxic

30

Involved circulating antigen-antibody complexes that deposit in post capillary venules, with subsequent complement fixation

type 3 hypersensitivty reaction -- also called serum sickness

31

Dogs receiving the CAV-1 or less likely the CAV-2 vaccine can develop immune-complexes in the eye and result in_____

anterior uveitis -- this is type 3 hypersensitivity

32

vaccine reaction mediated by T cells not antibodies

delayed hypersensitivity reaction -- type 4

33

type 4 delayed hypersensitivity reaction is not common but can be seen when ___ is used as an immunostimulant compoung

BCG

34

breed predisposed to Polyradiculoneuritis

coon hounds

35

causes LMN 1-2 weeks post vaccination

Polyradiculoneuritis

36

Polyradiculoneuritis is from a specific rabies vax derived from what

suckling mouse brains

37

Most viruses are grown in cell cultures that contain serum from??

bovine fetuses

38

ischemic dermatopathy vax rxn

Widespread cutaneous vasculitis – ulceration, crusting, hyperpigmentation and alopecia

associated with rabies 1-5 months post vaccination

39

adjuvants in FeLV that causes injection site sarcomas in cats

aluminum

incidence of 1 in 10 000 vaccinated cats

40

Encephalomyelitis from the MLV of what

rabies

41

T/F
CPV or FPV vaccines are not to be given to pregnant females or animals < 4 weeks of age

true

42

Sudden onset of lameness between 3 and 15 days post vaccination

polyarthritis in dogs

43

Vaccine associated hypertrophic osteodystrophy and juvenile cellulitis is especially noted in what breed

weimaraners

44

Immune-mediated polyarthritis in young akitas occurs how many days post MLV

3-29 days
*clinical signs start at around 16 weeks

45

what is used for treatment in Immune-mediated polyarthritis in young akitas

corticosteroids can help with the inflammation but these dogs are usually euthanized by age 2 due to the progression and poor quality of life

46

what is a core vaccine

All dogs and cats, regardless of geographical location or circumstance
• Protect against life threatening disease

47

vaccines Only required in specific geographical locations, local environments or lifestyle places

non-core vaccine

48

how often should vaccines be given to puppy or kitten and until when

start at 6-8 weeks old and give them every 2-4 weeks until 16 weeks old

49

T/F
If the dog is > 16 weeks then a single vaccination is sufficient

true

50

3 core vaccines for cats

FPV, FHV-1, FCV

51

which vaccines are carried out annually in high risk cats

FHV-1 and FCV

52

core vaccines in dogs

CDV, CPV-2, CAV
and rabies

53

T/F
vaccinate all cats for FeLV

false - only vaccinate negative cats

54

T/F
Chlamydophila and bordetella require tri-annual vaccinations

FALSE -- annual

55

Adjuvanted FeLV and rabies vaccination has been associated with ____

FISS

56

where do we give the FeLV vax

left leg

57

where do we give the rabies vax

right leg