Vancomycin

Question 1

Generic Name for Vancocin

Answer 1

Vancomycin

Question 2

Trade Name for Vancomycin

Answer 2

Vancocin

Question 3

Classification for Vancomycin

Answer 3

Antibiotic

Question 4

MOA (pharmacodynamics) for Vancomycin

Answer 4

Binds to bacterial cell membranes, inhibits wall synthesis; bactericidal

Question 5

Indications for Vancomycin Admin

Answer 5

Treatment of susceptible infections due to gram-positive aerobic bacteria like staphylococcus. It treats complicated skin infections, bloodstream infections, endocarditis, bone/joint infections and meningitis. Often used to treat MRSA.

Question 6

Dosages for Vancomycin Admin

Answer 6

Adult: 25-30mg/kg IV/IO ideal body weight.

• doses 1g or less; Infuse over 60 minutes
• doses 1g to 1.5g; Infuse over 90 minutes
• doses over 1.5g; Infuse over 120 minutes

Pediatric: 15mg/kg to a max of 1000mg IV/IO, infuse over 60 minutes

Question 7

Contraindications for Vancomycin Admin

Answer 7

1. Hypersensitivity
2. Hemolytic anemia
3. c.difficile associated diseases
4. Do not administer with calcium containing IV solutions such as ringers lactate.

Question 8

Precautions in using Vancomycin

Answer 8

• Rapid injection may cause Red Man syndrome (anaphylactoid reaction causing hives, swelling, rash to face, hands, neck and upper torso).
• Slowing the infusion rate and increasing dilution volume may prevent or minimize this reaction
• Administering an antihistamine prior to the infusion may reduce symptoms

Question 9

Notable Notes to Note regarding Vancomycin

Answer 9

• Abdominal cramping, severe watery diarrhea, and fever may result from an altered bacterial balance.
• Use caution in patients with impaired renal function and patients with previous hearing problems.