Vascular System Flashcards
This deck covers Chapters 75-78 in Rosens, compromising all of vascular medicine.
List 8 risk factors for aortic dissection
- Age
- Male
- HTN
- Cardiac surgery
- Bicuspid valve
- FHx
- Ehlers-Danlos
- Marfan’s
- Cocaine use
- Trauma
- Exertion
- IABP insertion
- Congenital heart disease
List 2 classification systems for aortic dissection
Stanford (2 syllables)
- Type A - ascending
- Type B - descending
DeBakey (3 syllables)
- Type I - ascending + descending
- Type II - ascending
- Type III - descending
List 10 findings on CXR for aortic dissection.
- Wide mediastinum
- Abnormal aortic contour
- Calcium sign
- Double egg sign
- Loss of PA window
- Loss of aortic knob
- Apical cap
- Pleural effusion
- Displacement of NG right
- Right mainstem displaced right
- Left mainstem displaced down
What is your HR and BP target in aortic dissection? Which do you get first?
- HR < 60 bpm
- sBP <110 mmHg
Achieve HR goal first to avoid reflex tachycardia
List 2 reasons why NIFEDIPINE should not be used in aortic dissection.
- Reflex tachycardia
- Doesn’t slow HR
List 4 risk factors for AAA. What is the most important risk factor for the risk of rupture?
- Age
- Male
- FHx
- HTN
- Smoking
- DLD
Rate of size increase is most concerning
Size >5.5 cm = surgery
List 7 complications that can arise from an INTACT AAA
- Rupture
- Aortic thrombosis
- Embolization
- Paralysis
- AKI
- Limb ischemia
- Aortocaval fistula
- Aortoenteric fistula
List 4 late complications of AAA repair
- Endoleak
- Infection
- Aortoenteric fistula
- Pseudoaneurysm
Explain the 4 types of endoleak
Type I
- Leak from end of graft
Type II
- Leakage into aneurysm sac from branch vessels
Type III
- Leak between stent components
Type IV
- Leak through graft material
How is arterial embolism best managed?
Embolism
- Fogarty Catheter Embolectomy
Thrombus
- Fogarty Catheter Embolectomy
- Bypass Graft
Non-Limb Threatening
- Heparin
- Intra-arterial tPA
Amputate if irreversible ischemia
What is Buerger’s sign?
- Patient supine, raise leg 45 degrees
- When feet have pallor, sit with hanging over edge
- Normal if colour returns in 10-15s
- Advanced ischemia if >20s
- Ischemic if cyanotic first, then red
How do you differentiate embolus from thrombosis?
Embolus
- Usually have afib
- Other leg is normal, no claudication
- Sharp demarcation of ischemia
- Few collaterals
Thrombus is opposite
What are the 5 diagnostic criteria of Buerger’s disease? What is the only treatment?
- Smoker
- Absence of atherosclerotic risk factors
- Onset <50 yo
- Infrapopliteal arterial occlusions
- Upper limb involvement
Treatment
- Stop smoking
Differentiate phlegmasia cerulea dolens & phlegmasia alba dolens
Phlegmasia cerulea dolens
- Massive iliofemoral DVT
- Cyanotic leg
Phlegmasia alba dolens
- Arterial insufficiency from massive iliofemoral DVT
- White leg
List 5 diagnostic criteria for Raynaud’s disease.
- Symptoms >2yr
- Worse in cold/emotion
- Bilateral
- No gangrene
- No disease that causes Raynaud’s phenomenon
- Scleroderma, SLE, RA
White –> Blue –> Red
22 yo male with months of severe pain in the ulnar distribution of his left arm. Worse at work (stocks overhead shelves). Diagnosis? Best test?
Thoracic Outlet Syndrome
Elevated Arm Stress Test (EAST)
- Most reliable screening test
- Abduct arm and elbow to 90 degrees
- Open/close fists for 3 min
- Positive if:
- Early fatigue
- Numb hand
- Progressive aching to top of arm/shoulder
List 8 DDx for DVT
- Muscle strain, hematoma
- Baker’s cyst
- Lymphedema
- Cellulitis
- Vasculitis
- Fracture
- Superficial phlebitis
- Chronic venous insufficiency
- Proximal venous compression (pregnancy, tumour)
- CHF
- Hypoalbuminemia
What are the 10 components of the Well’s Score for DVT?
C3P3O R2D2 - note it is not C3PO
- Cancer
- Collateral superficial veins
- Calf swelling >3 cm larger than other
- Pitting edema
- Previous DVT
- Pain along the deep venous system
- Oedema of the entire leg
- Recent immobilization
- Recent surgery (3mo)
- Different diagnosis more likely (-2)
If 2+, get U/S. If 0/1, get D-dimer
List the dose of the following mediations in treatment of DVT:
- UFH
- Enoxaparin
- Dalteparin
- Rivaroxaban
- UFH 80 units/kg IV bolus, then 18 units/kg IV infusion
- Enoxaparin 1 mg/kg SC BID
- Dalteparin 100 units/kg SC BID
- Rivaroxaban 15 mg PO BID
Name 3 absolute contraindications for treating a proximal DVT.
- Active bleeding
- Bleeding diathesis
- PLT <20
- Intracranial bleed
- Recent NSx/Ocular Sx
What are the 7 components of the Well’s Score for PE?
Don’t Die Tell Team To Calculate Criteria
- DVT symptoms (3)
- Diagnosis most likely PE (3)
- Tachycardia (1.5)
- Three days immobilized/30 days surgery (1.5)
- Thromboembolism in the past (1.5)
- Cancer (1)
- Coughing blood (1)
If score >4, CT. If score 4 or less, D-dimer
What are the 8 criteria in the PERC rule?
HAD CLOTS
- Hormones
- Age >50
- DVT/PE history
- Coughing blood
- Leg swelling
- Oxygen >95%
- Tachycardia
- Surgery in last month
What are 5 CXR findings of PE?
- Hampton’s hump
* Wedge-like opacity at the edge (infarct) - Westermark’s sign
* Unilateral lung oligemia - Fleischner’s sign
* Enlarged pulmonary artery - Pleural effusion
- Unilateral basal atelectasis
List 5 ECG findings that can occur with PE
- Sinus tachycardia
- TWI V1-V4
- RBBB
- RAD
- S1Q3T3
- ST changes
- Afib
What are 6 treatments available in massive PE?
- Anticoagulation
- Fluid resuscitation
- Vasopressors/Inotropes
- tPA
- Catheter-directed tPA
- Embolectomy
What is the dose of tPA in massive PE? How do you give it?
Dose = 0.9 mg/kg
The administration is contentious.
- If dead, 50% upfront, 50% over 1 hr
- If not dead, perhaps 15% upfront, 85% over 1 hr
Define massive PE
- Cardiac arrest
- Profound hypotension (sBP <90)
- Bradycardia <40 bpm
List 3 indications for tPA in massive PE
- Cardiac arrest
- Persistent hypotension
- Cardiogenic shock
These are basically the definition of massive PE
List 8 absolute contraindications for tPA
Absolute
- Active bleeding
- AVM
- Brain cancer
- ICH
- Aortic dissection
- Severe hypertension
- Closed head injury within 3 months
- Stroke within 3 months
- Brain/Spine Sx within 2 months
List 8 relative contraindications for tPA
Relative
- Severe hypertension
- Other intracranial diseases
- CPR >10 min
- Surgery within 3 weeks
- GI bleed within 3 weeks
- Plt <100
- Non-compressible vascular access
- Pregnancy
- OAC