Pediatrics Flashcards
This deck covers Chapters 160-177 in Rosens, compromising all of pediatrics.
What medication should be given to babies (~2-3 weeks) presenting with cyanotic CHD? Dose? Side effects?
PGE1 0.05-0.1 ug/kg/min IV infusion
Side effects:
- Fever
- Seizure
- Apnea
- Hypotension
- Bradycardia
List 7 anatomical differences in children and the relevance.
- Large surface to weight ratio = More heat loss
- Large head, floppy neck = Higher rate of head injury
- Narrow airway = More easily obstructed
- CV Compromise/Hypotension is late = Well until crashing
- Pliable bones = More force to vital organs
- Physeal plates are weakest = Growth plate injuries
- Nose breathers = Secretions cause significant WOB
List 5 causes of decreased stroke volume in children
- Dehydration
- Pericarditis w/ tamponade
- Myocarditis
- CHF
- HOCM
- Dilated cardiomyopathy
- Tachydysrhythmias
List 6 treatment options for a child having a “tet spell”
- Oxygen
- Knee-to-chest
- Calm the child
- Morphine 0.1 mg/kg IV/IM
* Fentanyl 1 ug/kg IV/IM - Ketamine 1 mg/kg IV
- Phenylephrine 20 ug/kg IV
- Propranolol 0.01 - 0.02 mg/kg IV
* Esmolol 500 ug/kg bolus IV
What are the historical features (4) concerning for child abuse?
- Lacking details
- Inconsistent on repeat questioning
- Inconsistent with developmental status
- Inconsistent mechanism with injury
Draw a diagram outlining fetal circulation.
From mom, through umbilical vein (1)
Bypass liver via ductus venosus
Enter heart at IVC
Bypass lungs via patent foramen ovale to aorta
Bypass RV via patent ductus arteriosus to aorta
Blood then leaves placenta via umbilical arteries (2)
List 5 infectious and 3 non-infectious causes of HUS
Why are antibiotics contraindicated?
Infectious
- E. coli O157:H7
- Shigella
- S. pneumoniae
- Aeromonas
- HIV
Non-Infectious
- Drugs
- Hereditary
- Familial
- Idiopathic
ABx enhances release of bacterial verotoxin
What is the peak age for SCFE?
Name 6 associations with SCFE
Peak age = 12 y/o, older in boys
- Male
- Obesity
- Black
- Endocrine disorders
- Radiation therapy
- Renal osteodystrophy
List 6 causes of childhood ataxia
- Acute cerebellar ataxia
- Post-infectious demyelinating encephalomyelitis
- Brainstem encephalitis
- Drug ingestion
- Inborn errors of metabolism
- Migraine
- MS
- Brain mass
- Seizures
- Stroke
- Vertebral artery dissection
List 4 CHDs that are duct dependent for Left to Right
- Duct required to get blood into pulmonary circulation
List 3 CHDs that are duct dependent for Right to Left
- Duct required to get blood into the arterial circulation
Left to Right
- Pulmonary atresia
- Tricuspid atresia
- Tetralogy of Fallot
- Hypoplastic right heart
- TGA
Right to Left
- Hypoplastic left heart
- Pre-ductal coarctation
- Severe aortic stenosis
List 8 episodic disorders that may mimic seizures in children
- BRUE
- Breath-holding spell
- Rigors
- GERD
- Migraine
- BPPV
- Syncope
- Stroke
- Sleep disorders
- Movement disorders
- Psychogenic seizure
Provide a DDx for a systolic murmur in the following locations:
- LUSB
- LLSB
- RUSB
- Apex
LUSB
- Pulmonary stenosis
- PDA
- Flow murmur
- ASD
LLSB
- Tricuspid regurgitation
- Still’s murmur
- VSD
- Tetralogy
- HOCM
RUSB
- Aortic stenosis
- Coarctation
Apex
- Mitral regurgitation
- Still’s murmur
- HOCM
Provide 2 congenital and 2 acquired causes of stridor in each of supraglottic, glottic, and infraglottic areas.
_Congenital_
- Supraglottic
- Micrognathia
- Pierre Robin syndrome
- Treacher Collins
- Thyroglossal duct cyst
- Lingual thyroid
- Choanal atresia
- Down syndrome
- Macroglossia
- Storage diseases
- Glottic
- Laryngomalacia
- Vocal cord paralysis
- Laryngeal web
- Laryngocele
- Infraglottic
- Subglottic stenosis
- Tracheomalacia
- Tracheal stenosis
- Vascular ring
- Hemangioma cyst
_Acquired_
- Supraglottic
- Foreign body
- Pharyngeal abscess
- Epiglottitis
- Tonsillar hypertrophy
- Adenopathy
- Glottic
- Foreign body
- Papillomas
- Infraglottic
- Foreign body
- Croup
- Bacterial tracheitis
- Subglottic stenosis
List the most common organism for each of croup, epiglottitis, and bacterial tracheitis.
- Croup = Parainfluenza virus
- Epiglottitis = H. flu
- Bacterial tracheitis = S. aureus
List 10 causes of vomiting in children
- Meningitis
- Brain mass
- Overdose
- DKA
- CAH
- UTI
- CHF
- Pneumonia
- AOM
- Sepsis
- Any GI issue…
List the normal vital signs by age (HR, RR, BP)
Heart Rate
- <1 year = 100 - 160
- 1-2 years = 90 - 150
- 2-5 years = 80 - 140
- 5-12 years = 70 - 120
- 12+ years = 60 - 100
Respiratory Rate
- <1 year = 30 - 60
- 1-2 years = 24 - 40
- 2-5 years = 22 - 34
- 5-12 years = 18 - 30
- 12+ years = 12 - 16
Blood Pressure
- <1 month = 60 mmHg
- 1-12 months = 70 mmHg
- 1-10 years = 70 + (Age x 2)
How do you manage bronchiolitis in the ED?
Name 2 treatments that have evidence for, 2 against, and 2 equivocal.
Treatment = Supportive
Evidence for:
- Oxygen
- Hydration
Equivocal:
- Nebulized epinephrine + Dexamethasone
- Nasal suction
Against:
- Ventolin/Atrovent
- Steroids
- Antibiotics
- Hypertonic Saline
List 8 things on a DDx for bacterial meningitis
- Stroke
- Brain bleed
- CNS vasculitis
- SAH
- AOM
- Sepsis
- Meningitis
- Encephalitis
- Brain abscess
- Brain mass
- Sympathomimetics
- ASA
- Anticholinergics
- Thyrotoxicosis
- NMS
- SS
- MH
- Heat stroke
- Viral URTI
What is the CPS statement on steroids in meningitis?
Dexamethasone 0.6 mg/kg IV div q6h
- Give within 4h of ABx (earlier is likely better)
- Mortality benefit with S. pneumoniae
- Hearing loss benefit with H. influenzae
What investigations would you order as a “critical sample”?
Usual
- Electrolytes
- LFTs
- Glucose
- Lactate
Nutrients
- Ketones
- Free Fatty Acids
- Amino Acids
Hormones
- Growth Hormone
- Cortisol
- Insulin
What are the diagnostic criteria for Kawasaki disease?
CREAM
Fever >5 days plus 4 of the following:
- Conjunctivitis (bilateral, non-suppurative)
- Rash (generalized maculopapular rash)
- Extremity changes (swelling/red, sloughing on hands/feet)
- Adenopathy (>1.5 cm)
- Mucosal involvement (Strawberry tongue, red lips/throat)
What is the treatment of phimosis?
- Topical steroids (Betamethasone x6 weeks)
- Dilation
- Dorsal slit/Circumcision
How is the desired amount of ORT estimated and given?
- Estimate degree of dehydration
- Mild 30 mL/kg, Mod 60 mL/kg, Sev 90 mL/kg
- Calculate the desired volume
- Multiply weight by severity
- Replace ongoing losses
- 10 mL/kg per stool
- 2 mL/kg per vomit
- Administer 25%/hr x4 hr
- Re-evaluate at 4 hours
What is the etiology and treatment for septic arthritis by age?
- 0-2 months
- 2 months - 5 years
- 5 - 12 years
- >12 years
0-2 months
- GBS
- S. aureus
- N. gonorrhea
2 months - 5 years
- S. aureus
- Streptococcus
- Kingella
- H. influenzae
5 - 12 years
- S. aureus
- Streptococcus pyogenes
>12 years
- S. aureus
- N. gonorrhea
Treatment
- Cefotaxime/Ceftriaxone + Vancomycin
How do you manage an upper airway obstruction in an infant (<1 year) vs. a child (>1 year)?
Infant (<1 yr)
- 5x back blows then 5x chest compressions
Child (>1 yr)
- Heimlich
If unconscious, start CPR. No blind finger sweeps.
Needle cric if necessary
- 14-18G needle on a 3 mL syringe without the plunger
- Connect to BVM using 3-0 ETT connector
Review the developmental milestones in children <2 years old
List 10 drugs that may cause seizures
OTIS CAMPBELL
- Oral hypoglycemic
- Theophylline, TCA
- Insulin, Isoniazid
- Sulphonylureas, Sympathomimetics
- Camphor, Cocaine, CO
- ASA, Anticholinergics
- Methanol
- PCP, pesticides
- Botanicals, BZD/Barbituate w/d
- Ethylene glycol, Ethanol w/d
- Lidocaine
- Lithium
Outline the Boston Criteria
- Age 28-89 days
- Fever >38.0 degrees
- Well looking
- Labs
- WBCs < 20
- UA < 10 WBCs/hpf
- CSF <10 WBCs/hpf
- CXR normal (if obtained)
- NPV 94.6%
- All children received a dose of IM ceftriaxone
List 3 conditions that cause a double-bubble sign on AXR
- Pyloric stenosis (non-bilious - 4 weeks progressive)
- Duodenal atresia (bilious - immediate)
- Midgut volvulus (bilious - 4 weeks sudden)
List 4 indications for LP in suspected acute bacterial meningitis
- Fever <60 days
- Neonatal sepsis
- Altered mental status/Neck stiffness
- Suspected sepsis in abnormal host
- Consider in:
* Fever + Seizure
* Fever + Petechiae
* Fever + Contact
Name 6 risk factors for meningitis in children
- Neonate
- Native
- Black
- Malnourished
- Low SES
- Daycare
- Sickle Cell
Immune Compromise
- AIDS
- Asplenia
- Renal Disease
- Hepatic Disease
- DM
- Dysgammaglobulinemia
- Immunosuppressive medication
What is the peak age for Legg-Calve Perthes disease?
Name 8 associations with the disease.
Peak age = 7 y/o
- Male
- Breech
- Low birth weight
- Later birth order
- Older parents
- Short
- Asian
- Low SES
- HIV
- Renal disease
Describe the Salter-Harris classification system
- Straight
- Above
- beLow
- Through
- cRush
Give a DDx for conjugated and unconjugated jaundice in an infant.
Conjugated
- Obstructive
* Biliary atresia
* Bile duct stricture
* Choledochal cyst - Infectious
* Sepsis
* TORCH infection - Metabolic/Genetic
* Cystic fibrosis
* Galactosemia
* Alpha-1 antitrypsin deficiency
Unconjugated
- Hemolysis
* G6PD
* Spherocytosis
* Sickle Cell
* ABO incompatibility
* Cephalohematoma - Infectious
* Sepsis
* TORCH infection - Obstructive
* Duodenal atresia
* Pyloric stenosis - Metabolic/Genetic
* Galactosemia
* Crigler-Nejar syndrome
* Gilbert syndrome
What is the treatment for paraphimosis?
- Analgesia (nerve block)
- Reduce edema (ice)
- Reduce foreskin (two thumbs, pull shaft)
List 6 cardiovascular causes of sudden death in an athlete.
- HOCM
- Brugada
- WPW
- ARVD
- Commotio cordis
- Long QT
- Mitral valve prolapse
- Coronary disease from Kawasaki
- Aortic rupture from Marfans
- Dilated cardiomyopathy
- Myocarditis
- Aortic stenosis
- Congenital coronary anomaly
What is the inpatient and outpatient antibiotic regimen for pneumonia treatment in children >3 months?
Outpatient
- Amoxicillin 90 mg/kg/day TID x10 days
- PCN Allergic: Clarithromycin 7.5 mg/kg BID x10 days
Inpatient
- Ceftriaxone 50-100 mg/kg q24h
and
- Azithromycin 10 mg/kg on day 1, 5 mg/kg on days 2-5
What are the 4 radiographic classification stages of Legg-Calve-Perthes disease?
- Initial - femoral head smaller than opposite
- Fragmentation - epiphysis fragments
- Re-ossification - bone density restores
- Healed - residual deficits remain
List 3 ways to estimate ETT size for children >1 y/o?
- Breslow tape
- Diameter of little finger
- Cuffed = 3.5 + (age/4)
How do you counsel a parent regarding febrile seizures?
- Risk of epilepsy from 1% to 2%
- 30% of kids will have another
- Younger they are, higher the risk
- During seizure
- Protect from injury, nothing in mouth
- If seizure <5 min
- Check airway, recovery position, seek MD advice
- If seizure >5 min
- Call 911
List 7 factors associated with priapism
- Sickle cell
- Leukemia
- Anticoagulation
- Immunosuppression
- Trauma
- Spinal cord injury
- Drugs - SSRI, sedatives OAC, abuse
List 4 organism that cause a ‘whooping cough’
- B. pertussis
- C. pneumoniae
- M. pneumoniae
- Adenovirus
What risk factors (8) are referred to in the phototherapy guidelines for risk of bilirubin related encephalopathy?
Some Ailing Babies Have to Get Lower Phototherapy Thresholds
- Sepsis
- Albumin <30
- Blue (Asphyxia)
- Hemolysis
- G6PD
- Lethargy
- pH (Acidemia)
- Temperature instability
List 10 complications of status epilepticus
- Brain ischemia
- Tachycardia
- Hypertension
- Hyperpyrexia
- Rhabdomyolysis
- Hyperglycemia
- Lactic acidosis
- Aspiration
- Takotsubo cardiomyopathy
- CHF
- Apnea
- Neurogenic pulmonary edema
What is first-line treatment for pneumonia in 0-3 months?
0-30 days
- Ampicillin 50 mg/kg q8h + Cefotaxime 50 mg/kg q8h
30 - 90 days
- Ceftriaxone 100 mg/kg IV q24h
What does the CPS recommend in regards to the management of status epilepticus?
- Lorazepam 0.1 mg/kg IV, then
- Fosphenytoin/Phenytoin 20 mg/kg, then
- Phenobarbital 20 mg/kg, then
- RSI + Midaz infusion
When (10) would you work-up a child with acute diarrhea?
- <6 months
- Premature
- Chronic medical conditions
- Fever
- Bloody stool
- High output
- Persistent vomiting
- Dehydration
- Altered
- Poor ORT in ED
List 10 causes of diarrhea in children
- Overdose
- CAH
- Addisonian crisis
- Thyrotoxicosis
- UTI
- Pyelonephritis
- Pneumonia
- AOM
- Sepsis
- Malabsorption
- CF
- Intussusception
- IBD
- Gastroenteritis
- IBS
- Short gut syndrome
List 10 causes of HTN in children
- Essential HTN
- Conn’s
- Pheo
- Renal artery stenosis
- Coarctation
- Nephritic syndrome
- ICP
- Brain mass
- HSP
- PCKD
- SLE
- Diabetic nephropathy
- Cushing’s
- CAH
- Chronic steroids
- OCP
- Sympathomimetics
What are the risk factors (6) for febrile seizure recurrence?
- Age on onset <18 months
- Fever <39 degrees
- 1st-degree relative FHx
- Fever <1h before the seizure
- Multiple seizures in the same illness
- Daycare
What do you do if a child has a fever for 6 days and only 2 criteria for Kawasaki?
Incomplete Kawasaki Workup
- ESR >40 + CRP >30
- If not, stop
- If so, get: HgB, WBC, Plt, Alb, ALT, Urine
- HgB AbN
- WBC >15
- Plt >450
- Alb <30
- ALT AbN
- Sterile pyuria (>10 WBCs/hpf)
* If 3+ AbN, get an echo and treat
* If 0-2 AbN, get an echo
* If echo AbN treat
* If echo normal, stop
Name the top 3 bacterial causes of pneumonia by age:
- 0-3 weeks
- 3 weeks - 3 months
- 3 months - Adolescent
0-3 weeks
- E. coli
- GBS
- L. monocytogenes
3 weeks - 3 months
- C. trachomatis
- S. pneumoniae
- H. influenzae
3 months - Adolescent
- C. pneumoniae
- M. pneumoniae
- S. pneumoniae
What pediatric patients are at higher risk of UTI?
- Female < 2 years
- Male < 1 year uncircumsized
- Male < 6 months circumsized
*Send UCx even if dip negative
Name 13 infectious causes of diarrhea
- Campylobacter jejuni
- Clostridium difficile
- E. coli - STEC
- E. coli - ETEC
- Salmonella, non-typhoid
- Salmonella typhi
- Shigella
- Vibrio cholera
- Vibrio parahemolyticus
- Yersinia enterocolitica
- Cryptosporidium
- Entamoeba histolytica
- Giardia
List the 5 components of the Westley Croup Score.
What defines mild/moderate/severe?
CARLS
- Cyanosis (0/4/5)
- A/E (0/1/2)
- Retractions (0/1/2/3)
- Level of Consciousness (0/5)
- Stridor (0/1/2)
Mild = 0 - 2 (Dex 0.15-0.6 mg/kg then home)
Moderate = 3 - 5 (Dex 0.15-0.6 mg/kg then observe)
Severe = 6 - 11 (Dex 0.15-0.6 mg/kg + Epi 5 mL neb)
What is a Tillaux fracture? How is it managed?
SH3 fracture of the distal tibia epiphysis caused by an avulsion of the AITFL
Ortho to see in ED