Pediatrics Flashcards
This deck covers Chapters 160-177 in Rosens, compromising all of pediatrics.
What medication should be given to babies (~2-3 weeks) presenting with cyanotic CHD? Dose? Side effects?
PGE1 0.05-0.1 ug/kg/min IV infusion
Side effects:
- Fever
- Seizure
- Apnea
- Hypotension
- Bradycardia
List 7 anatomical differences in children and the relevance.
- Large surface to weight ratio = More heat loss
- Large head, floppy neck = Higher rate of head injury
- Narrow airway = More easily obstructed
- CV Compromise/Hypotension is late = Well until crashing
- Pliable bones = More force to vital organs
- Physeal plates are weakest = Growth plate injuries
- Nose breathers = Secretions cause significant WOB
List 5 causes of decreased stroke volume in children
- Dehydration
- Pericarditis w/ tamponade
- Myocarditis
- CHF
- HOCM
- Dilated cardiomyopathy
- Tachydysrhythmias
List 6 treatment options for a child having a “tet spell”
- Oxygen
- Knee-to-chest
- Calm the child
- Morphine 0.1 mg/kg IV/IM
* Fentanyl 1 ug/kg IV/IM - Ketamine 1 mg/kg IV
- Phenylephrine 20 ug/kg IV
- Propranolol 0.01 - 0.02 mg/kg IV
* Esmolol 500 ug/kg bolus IV
What are the historical features (4) concerning for child abuse?
- Lacking details
- Inconsistent on repeat questioning
- Inconsistent with developmental status
- Inconsistent mechanism with injury
Draw a diagram outlining fetal circulation.
From mom, through umbilical vein (1)
Bypass liver via ductus venosus
Enter heart at IVC
Bypass lungs via patent foramen ovale to aorta
Bypass RV via patent ductus arteriosus to aorta
Blood then leaves placenta via umbilical arteries (2)
List 5 infectious and 3 non-infectious causes of HUS
Why are antibiotics contraindicated?
Infectious
- E. coli O157:H7
- Shigella
- S. pneumoniae
- Aeromonas
- HIV
Non-Infectious
- Drugs
- Hereditary
- Familial
- Idiopathic
ABx enhances release of bacterial verotoxin
What is the peak age for SCFE?
Name 6 associations with SCFE
Peak age = 12 y/o, older in boys
- Male
- Obesity
- Black
- Endocrine disorders
- Radiation therapy
- Renal osteodystrophy
List 6 causes of childhood ataxia
- Acute cerebellar ataxia
- Post-infectious demyelinating encephalomyelitis
- Brainstem encephalitis
- Drug ingestion
- Inborn errors of metabolism
- Migraine
- MS
- Brain mass
- Seizures
- Stroke
- Vertebral artery dissection
List 4 CHDs that are duct dependent for Left to Right
- Duct required to get blood into pulmonary circulation
List 3 CHDs that are duct dependent for Right to Left
- Duct required to get blood into the arterial circulation
Left to Right
- Pulmonary atresia
- Tricuspid atresia
- Tetralogy of Fallot
- Hypoplastic right heart
- TGA
Right to Left
- Hypoplastic left heart
- Pre-ductal coarctation
- Severe aortic stenosis
List 8 episodic disorders that may mimic seizures in children
- BRUE
- Breath-holding spell
- Rigors
- GERD
- Migraine
- BPPV
- Syncope
- Stroke
- Sleep disorders
- Movement disorders
- Psychogenic seizure
Provide a DDx for a systolic murmur in the following locations:
- LUSB
- LLSB
- RUSB
- Apex
LUSB
- Pulmonary stenosis
- PDA
- Flow murmur
- ASD
LLSB
- Tricuspid regurgitation
- Still’s murmur
- VSD
- Tetralogy
- HOCM
RUSB
- Aortic stenosis
- Coarctation
Apex
- Mitral regurgitation
- Still’s murmur
- HOCM
Provide 2 congenital and 2 acquired causes of stridor in each of supraglottic, glottic, and infraglottic areas.
_Congenital_
- Supraglottic
- Micrognathia
- Pierre Robin syndrome
- Treacher Collins
- Thyroglossal duct cyst
- Lingual thyroid
- Choanal atresia
- Down syndrome
- Macroglossia
- Storage diseases
- Glottic
- Laryngomalacia
- Vocal cord paralysis
- Laryngeal web
- Laryngocele
- Infraglottic
- Subglottic stenosis
- Tracheomalacia
- Tracheal stenosis
- Vascular ring
- Hemangioma cyst
_Acquired_
- Supraglottic
- Foreign body
- Pharyngeal abscess
- Epiglottitis
- Tonsillar hypertrophy
- Adenopathy
- Glottic
- Foreign body
- Papillomas
- Infraglottic
- Foreign body
- Croup
- Bacterial tracheitis
- Subglottic stenosis
List the most common organism for each of croup, epiglottitis, and bacterial tracheitis.
- Croup = Parainfluenza virus
- Epiglottitis = H. flu
- Bacterial tracheitis = S. aureus
List 10 causes of vomiting in children
- Meningitis
- Brain mass
- Overdose
- DKA
- CAH
- UTI
- CHF
- Pneumonia
- AOM
- Sepsis
- Any GI issue…
List the normal vital signs by age (HR, RR, BP)
Heart Rate
- <1 year = 100 - 160
- 1-2 years = 90 - 150
- 2-5 years = 80 - 140
- 5-12 years = 70 - 120
- 12+ years = 60 - 100
Respiratory Rate
- <1 year = 30 - 60
- 1-2 years = 24 - 40
- 2-5 years = 22 - 34
- 5-12 years = 18 - 30
- 12+ years = 12 - 16
Blood Pressure
- <1 month = 60 mmHg
- 1-12 months = 70 mmHg
- 1-10 years = 70 + (Age x 2)
How do you manage bronchiolitis in the ED?
Name 2 treatments that have evidence for, 2 against, and 2 equivocal.
Treatment = Supportive
Evidence for:
- Oxygen
- Hydration
Equivocal:
- Nebulized epinephrine + Dexamethasone
- Nasal suction
Against:
- Ventolin/Atrovent
- Steroids
- Antibiotics
- Hypertonic Saline
List 8 things on a DDx for bacterial meningitis
- Stroke
- Brain bleed
- CNS vasculitis
- SAH
- AOM
- Sepsis
- Meningitis
- Encephalitis
- Brain abscess
- Brain mass
- Sympathomimetics
- ASA
- Anticholinergics
- Thyrotoxicosis
- NMS
- SS
- MH
- Heat stroke
- Viral URTI
What is the CPS statement on steroids in meningitis?
Dexamethasone 0.6 mg/kg IV div q6h
- Give within 4h of ABx (earlier is likely better)
- Mortality benefit with S. pneumoniae
- Hearing loss benefit with H. influenzae
What investigations would you order as a “critical sample”?
Usual
- Electrolytes
- LFTs
- Glucose
- Lactate
Nutrients
- Ketones
- Free Fatty Acids
- Amino Acids
Hormones
- Growth Hormone
- Cortisol
- Insulin
What are the diagnostic criteria for Kawasaki disease?
CREAM
Fever >5 days plus 4 of the following:
- Conjunctivitis (bilateral, non-suppurative)
- Rash (generalized maculopapular rash)
- Extremity changes (swelling/red, sloughing on hands/feet)
- Adenopathy (>1.5 cm)
- Mucosal involvement (Strawberry tongue, red lips/throat)
What is the treatment of phimosis?
- Topical steroids (Betamethasone x6 weeks)
- Dilation
- Dorsal slit/Circumcision
How is the desired amount of ORT estimated and given?
- Estimate degree of dehydration
- Mild 30 mL/kg, Mod 60 mL/kg, Sev 90 mL/kg
- Calculate the desired volume
- Multiply weight by severity
- Replace ongoing losses
- 10 mL/kg per stool
- 2 mL/kg per vomit
- Administer 25%/hr x4 hr
- Re-evaluate at 4 hours
What is the etiology and treatment for septic arthritis by age?
- 0-2 months
- 2 months - 5 years
- 5 - 12 years
- >12 years
0-2 months
- GBS
- S. aureus
- N. gonorrhea
2 months - 5 years
- S. aureus
- Streptococcus
- Kingella
- H. influenzae
5 - 12 years
- S. aureus
- Streptococcus pyogenes
>12 years
- S. aureus
- N. gonorrhea
Treatment
- Cefotaxime/Ceftriaxone + Vancomycin
How do you manage an upper airway obstruction in an infant (<1 year) vs. a child (>1 year)?
Infant (<1 yr)
- 5x back blows then 5x chest compressions
Child (>1 yr)
- Heimlich
If unconscious, start CPR. No blind finger sweeps.
Needle cric if necessary
- 14-18G needle on a 3 mL syringe without the plunger
- Connect to BVM using 3-0 ETT connector
Review the developmental milestones in children <2 years old

List 10 drugs that may cause seizures
OTIS CAMPBELL
- Oral hypoglycemic
- Theophylline, TCA
- Insulin, Isoniazid
- Sulphonylureas, Sympathomimetics
- Camphor, Cocaine, CO
- ASA, Anticholinergics
- Methanol
- PCP, pesticides
- Botanicals, BZD/Barbituate w/d
- Ethylene glycol, Ethanol w/d
- Lidocaine
- Lithium
Outline the Boston Criteria
- Age 28-89 days
- Fever >38.0 degrees
- Well looking
- Labs
- WBCs < 20
- UA < 10 WBCs/hpf
- CSF <10 WBCs/hpf
- CXR normal (if obtained)
- NPV 94.6%
- All children received a dose of IM ceftriaxone
List 3 conditions that cause a double-bubble sign on AXR
- Pyloric stenosis (non-bilious - 4 weeks progressive)
- Duodenal atresia (bilious - immediate)
- Midgut volvulus (bilious - 4 weeks sudden)
List 4 indications for LP in suspected acute bacterial meningitis
- Fever <60 days
- Neonatal sepsis
- Altered mental status/Neck stiffness
- Suspected sepsis in abnormal host
- Consider in:
* Fever + Seizure
* Fever + Petechiae
* Fever + Contact
Name 6 risk factors for meningitis in children
- Neonate
- Native
- Black
- Malnourished
- Low SES
- Daycare
- Sickle Cell
Immune Compromise
- AIDS
- Asplenia
- Renal Disease
- Hepatic Disease
- DM
- Dysgammaglobulinemia
- Immunosuppressive medication
What is the peak age for Legg-Calve Perthes disease?
Name 8 associations with the disease.
Peak age = 7 y/o
- Male
- Breech
- Low birth weight
- Later birth order
- Older parents
- Short
- Asian
- Low SES
- HIV
- Renal disease
Describe the Salter-Harris classification system
- Straight
- Above
- beLow
- Through
- cRush
Give a DDx for conjugated and unconjugated jaundice in an infant.
Conjugated
- Obstructive
* Biliary atresia
* Bile duct stricture
* Choledochal cyst - Infectious
* Sepsis
* TORCH infection - Metabolic/Genetic
* Cystic fibrosis
* Galactosemia
* Alpha-1 antitrypsin deficiency
Unconjugated
- Hemolysis
* G6PD
* Spherocytosis
* Sickle Cell
* ABO incompatibility
* Cephalohematoma - Infectious
* Sepsis
* TORCH infection - Obstructive
* Duodenal atresia
* Pyloric stenosis - Metabolic/Genetic
* Galactosemia
* Crigler-Nejar syndrome
* Gilbert syndrome
What is the treatment for paraphimosis?
- Analgesia (nerve block)
- Reduce edema (ice)
- Reduce foreskin (two thumbs, pull shaft)
List 6 cardiovascular causes of sudden death in an athlete.
- HOCM
- Brugada
- WPW
- ARVD
- Commotio cordis
- Long QT
- Mitral valve prolapse
- Coronary disease from Kawasaki
- Aortic rupture from Marfans
- Dilated cardiomyopathy
- Myocarditis
- Aortic stenosis
- Congenital coronary anomaly
What is the inpatient and outpatient antibiotic regimen for pneumonia treatment in children >3 months?
Outpatient
- Amoxicillin 90 mg/kg/day TID x10 days
- PCN Allergic: Clarithromycin 7.5 mg/kg BID x10 days
Inpatient
- Ceftriaxone 50-100 mg/kg q24h
and
- Azithromycin 10 mg/kg on day 1, 5 mg/kg on days 2-5
What are the 4 radiographic classification stages of Legg-Calve-Perthes disease?
- Initial - femoral head smaller than opposite
- Fragmentation - epiphysis fragments
- Re-ossification - bone density restores
- Healed - residual deficits remain
List 3 ways to estimate ETT size for children >1 y/o?
- Breslow tape
- Diameter of little finger
- Cuffed = 3.5 + (age/4)
How do you counsel a parent regarding febrile seizures?
- Risk of epilepsy from 1% to 2%
- 30% of kids will have another
- Younger they are, higher the risk
- During seizure
- Protect from injury, nothing in mouth
- If seizure <5 min
- Check airway, recovery position, seek MD advice
- If seizure >5 min
- Call 911
List 7 factors associated with priapism
- Sickle cell
- Leukemia
- Anticoagulation
- Immunosuppression
- Trauma
- Spinal cord injury
- Drugs - SSRI, sedatives OAC, abuse
List 4 organism that cause a ‘whooping cough’
- B. pertussis
- C. pneumoniae
- M. pneumoniae
- Adenovirus
What risk factors (8) are referred to in the phototherapy guidelines for risk of bilirubin related encephalopathy?
Some Ailing Babies Have to Get Lower Phototherapy Thresholds
- Sepsis
- Albumin <30
- Blue (Asphyxia)
- Hemolysis
- G6PD
- Lethargy
- pH (Acidemia)
- Temperature instability
List 10 complications of status epilepticus
- Brain ischemia
- Tachycardia
- Hypertension
- Hyperpyrexia
- Rhabdomyolysis
- Hyperglycemia
- Lactic acidosis
- Aspiration
- Takotsubo cardiomyopathy
- CHF
- Apnea
- Neurogenic pulmonary edema
What is first-line treatment for pneumonia in 0-3 months?
0-30 days
- Ampicillin 50 mg/kg q8h + Cefotaxime 50 mg/kg q8h
30 - 90 days
- Ceftriaxone 100 mg/kg IV q24h
What does the CPS recommend in regards to the management of status epilepticus?
- Lorazepam 0.1 mg/kg IV, then
- Fosphenytoin/Phenytoin 20 mg/kg, then
- Phenobarbital 20 mg/kg, then
- RSI + Midaz infusion
When (10) would you work-up a child with acute diarrhea?
- <6 months
- Premature
- Chronic medical conditions
- Fever
- Bloody stool
- High output
- Persistent vomiting
- Dehydration
- Altered
- Poor ORT in ED
List 10 causes of diarrhea in children
- Overdose
- CAH
- Addisonian crisis
- Thyrotoxicosis
- UTI
- Pyelonephritis
- Pneumonia
- AOM
- Sepsis
- Malabsorption
- CF
- Intussusception
- IBD
- Gastroenteritis
- IBS
- Short gut syndrome
List 10 causes of HTN in children
- Essential HTN
- Conn’s
- Pheo
- Renal artery stenosis
- Coarctation
- Nephritic syndrome
- ICP
- Brain mass
- HSP
- PCKD
- SLE
- Diabetic nephropathy
- Cushing’s
- CAH
- Chronic steroids
- OCP
- Sympathomimetics
What are the risk factors (6) for febrile seizure recurrence?
- Age on onset <18 months
- Fever <39 degrees
- 1st-degree relative FHx
- Fever <1h before the seizure
- Multiple seizures in the same illness
- Daycare
What do you do if a child has a fever for 6 days and only 2 criteria for Kawasaki?
Incomplete Kawasaki Workup
- ESR >40 + CRP >30
- If not, stop
- If so, get: HgB, WBC, Plt, Alb, ALT, Urine
- HgB AbN
- WBC >15
- Plt >450
- Alb <30
- ALT AbN
- Sterile pyuria (>10 WBCs/hpf)
* If 3+ AbN, get an echo and treat
* If 0-2 AbN, get an echo
* If echo AbN treat
* If echo normal, stop
Name the top 3 bacterial causes of pneumonia by age:
- 0-3 weeks
- 3 weeks - 3 months
- 3 months - Adolescent
0-3 weeks
- E. coli
- GBS
- L. monocytogenes
3 weeks - 3 months
- C. trachomatis
- S. pneumoniae
- H. influenzae
3 months - Adolescent
- C. pneumoniae
- M. pneumoniae
- S. pneumoniae
What pediatric patients are at higher risk of UTI?
- Female < 2 years
- Male < 1 year uncircumsized
- Male < 6 months circumsized
*Send UCx even if dip negative
Name 13 infectious causes of diarrhea
- Campylobacter jejuni
- Clostridium difficile
- E. coli - STEC
- E. coli - ETEC
- Salmonella, non-typhoid
- Salmonella typhi
- Shigella
- Vibrio cholera
- Vibrio parahemolyticus
- Yersinia enterocolitica
- Cryptosporidium
- Entamoeba histolytica
- Giardia
List the 5 components of the Westley Croup Score.
What defines mild/moderate/severe?
CARLS
- Cyanosis (0/4/5)
- A/E (0/1/2)
- Retractions (0/1/2/3)
- Level of Consciousness (0/5)
- Stridor (0/1/2)
Mild = 0 - 2 (Dex 0.15-0.6 mg/kg then home)
Moderate = 3 - 5 (Dex 0.15-0.6 mg/kg then observe)
Severe = 6 - 11 (Dex 0.15-0.6 mg/kg + Epi 5 mL neb)
What is a Tillaux fracture? How is it managed?
SH3 fracture of the distal tibia epiphysis caused by an avulsion of the AITFL
Ortho to see in ED
List 5 fracture patterns that are worrisome for child abuse
- Non-linear skull fractures
- Long bone in a non-ambulatory child
- Posterior rib
- CML
- Vertebral body
- Fractures at different stages of healing
- Multiple fractures
- Any fracture <1-year-old
Compare and contrast extension vs flexion-type supracondylar fractures:
- How common?
- Mechanism?
- Physiology? What nerves are injured?
- Presentation?
How common?
- Extension = 95%
- Flexion = 5%
Mechanism?
- Extension = Hyperextension with FOOSH
- Flexion = Direct blow to flexed elbow
Physiology?
- Extension = Ant. cortex breaks with post. displacement
- Flexion = Post. cortex breaks with ant. displacement
Presentation?
- Extension = Holds in extension, arm in “S”
- Flexion = Holds in flexion, olecranon missing
Nerves Injured?
- # 1 anterior interosseous nerve (AIN) (branch of median n.)
- # 2 radial nerve palsy
- ulnar nerve palsy (seen with flexion-type)
What is a triplane fracture? How is it managed?
An angled fracture of the distal tibia in 3 planes
Age 10-17
Ortho in ED
What are the different lines on the phototherapy guideline?
- Term (>38) and well
- Term + risk factors OR 35-37+6 wk and well
- 35-37+6 wk + risk factors
List 8 complications from HSP
- Intussusception
- Renal failure
- Gallbladder hydrops
- Pancreatitis
- GI bleed
- Bowel ischemia
- Coronary artery vasculitis
- Headache
- Orchitis
List 8 causes of headache in children
- Stroke
- SAH
- AVM
- HTN
- Meningitis
- Encephalitis
- Brain abscess
- Brain mass
- Hydrocephalus
- AOM
- Cocaine
- Congenital malformation
- Abuse
- Dehydration
- Migraine
- UTI
- Pyelonephritis
- Pneumonia
- Medication S/E
List 10 causes of dysuria in a child
- UTI
- Pyelonephritis
- Renal colic
- Balanitis
- STI
- Vaginitis
- Pinworms
- Vaginal FB
- Chemical irritant (soap, bubble bath, etc.)
- Sexual abuse
- Masturbation
- Straddle injury
What are the most common causes of fever in the following age groups? Name 3 bacterial and 3 viral.
- 0-28 days
- 1-3 months
- 3-36 months
- 3 years - Adult

List the three components of the Pediatric Assessment Triage
- Appearance
- Circulation to Skin
- Work of Breathing
Provide a DDx (3) for cyanotic heart disease with decreased and increased vascular markings on CXR.
Increased vascular markings
- Transposition
- Truncus arteriosus
- TAPVR
- Hypoplastic left heart
Decreased vascular markings
- Tricuspid atresia
- Pulmonary atresia
- Tetralogy of Fallot
List 5 mimics of child abuse
- Metaphyseal cupping & spurring
- Osteogenesis imperfecta
- Rickets
- Scurvy
- Hypervitaminosis A
- Congenital syphilis
- Congenital rubella
- Periosteal new bone formation
What are the indications for IE prophylaxis for patients undergoing procedures? What procedures? What medication?
Indications
- History of IE
- Hardware
- CHD
- Transplant
Procedures
- Dental with mucosal involvement
- Resp incision
- Infected Skin
Prophylaxis
- Amoxicillin 50 mg/kg PO (max 2g)
- PCN Allergic: Clindamycin 20 mg/kg (max 600 mg)
- Give 30-60 minutes before procedure
Outline the Rochester Criteria
- Age < 60 days
- Fever >38.0 degrees
- Well looking
- Labs
- WBCs 5 - 15
- Bands < 1500
- UA < 10 WBCs/hpf
- Stool <5 WBCs/hpf
- Sens 92%
- NPV 98.9%
What are 4 conditions associated with severe RSV infection?
- Chronic lung disease
- Pulmonary hypertension
- Chronic heart disease
- Prematurity
- Immunodeficiency
List the pediatric doses for the following asthma medications:
- Ventolin MDI
- Ventolin Neb
- Atrovent MDI
- Atrovent Neb
- Dexamethasone
- Prednisone
- Methylprednisolone
- Epinephrine
- Magnesium sulfate
- Ventolin MDI
- <20 kg = 4 puffs
- >20 kg = 8 puffs
- Ventolin Neb
- <20 kg = 2.5 mg
- >20 kg = 5 mg
- Atrovent MDI
- <20 kg = 4 puffs
- >20 kg = 8 puffs
- Atrovent Neb
- <20 kg = 250 ug
- >20 kg = 500 ug
- Dexamethasone 0.6 mg/kg IV
- Prednisone 2 mg/kg (max 60 mg)
- Methylprednisolone 1-2 mg/kg (max 125 mg)
- Epinephrine 0.01 mg/kg IM
- Magnesium sulfate 50 mg/kg
What is the dose of:
- Cardioversion
- Defibrillation
- Epinephrine
- Atropine
- Adenosine
- Amiodarone
- Procainamide
- Lidocaine
- Magnesium
- Cardioversion = 1 J/kg
- Defibrillation = 2-4 J/kg
- Epinephrine = 0.01 mg/kg
- Atropine = 0.02 mg/kg
- Adenosine = 0.1 mg/kg
- Amiodarone = 5 mg/kg
- Procainamide = 15 mg/kg
- Lidocaine = 1 mg/kg
- Magnesium = 50 mg/kg
What are physical exam and radiographic findings (7) are concerning for child abuse?
- Bruising in young infant
- Patterned bruises/burns
- Bruises on ears/neck/trunk/inner thigh/groin
- Posterior rib fractures
- Classic metaphyseal fracture
- Any fracture in a non-ambulatory child
- Fractures of different stages of healing
List 8 conditions at high risk for developing arrhythmia
- Kawasaki
- Myocarditis
- CHD
- Congenital heart block
- WPW
- Long QT
- Rheumatic heart disease
- Commotio cordis
- Hypoxia
- Electrolytes
- Hypothermia
Name and describe 3 physical exam techniques to diagnose development dysplasia of the hip
-
Ortolani (Okay - reduces hip)
* Stabilize pelvis, abduct hip, pull up on thigh -
Barlow (Bad - dislocates hip)
* Stabilize pelvis, adduct hip, push down - Galeazzi Sign
- Femur length discrepancy by bending knees
What are 6 signs/symptoms of acute bilirubin encephalopathy?
- Arching
- Fever
- High-pitched cry
- Hypertonia
- Opisthotonos
- Retrocollis
What is the DDx for a child with altered mental status?
AEIOU TIPS
- Alcohol
- Electrolytes
- Infection
- Oxygen, Overdose
- Uremia
- Trauma, Tumour
- Insulin, Intussusception
- Psychiatric
- Seizure
Name 8 non-infectious causes of pneumonia-like presentation.
- Asthma
- FB
- Pneumothorax
- Congenital anomalies (TE fistula, bronchopulm. dysplasia)
- Pericarditis
- CHF
- Anaphylaxis
- Aspiration
- Cystic Fibrosis
- PE
When would you (in ED) reduce a supracondylar fracture?
Indications
- Pale, pulseless, cool hand by ED
- Pulseless but perfusing should be done by ortho!
Reduction
- In-line traction
- Correct lateral/medial displacement
- Hold elbow and flex elbow to 40 degrees
- Splint in place
What are the most common causes of jaundice in a newborn?
Breastfeeding jaundice
- Increased RBC mass
- Decreased hepatic uptake of bilirubin
- Increased hepatoenteric circulation of bilirubin
- Bilirubin normal at birth, peaks at day 3, normal by 1 week
Breast milk jaundice
- Mechanism unknown
- Bilirubin continues to rise, peaking at day 10-21
- Responds to withdrawal of breast milk for 48h
What is Baumann’s (outer) angle? What is it used for?
For subtle supracondylar fractures
- Line from growth plate of capitellum
- Line parallel to humeral shaft
Normal = 75 degrees or <5 degrees between sides
In SCFE, how is slip severity described?
As a percentage of displacement
- Mild =
- Moderate = ⅓ - ½
- Severe = >½
List the 7 acyanotic heart diseases
- ASD
- VSD
- Endocardial cushion defect
- PDA
- Aortic stenosis
- Pulmonic stenosis
- Coarctation
Describe the physiology of a “tet spell”
Crying causes a decrease in SVR
This causes a R-to-L shunt across the VSD
Hypoxia ensues
Describe how to perform the hyperoxia test
100% O2 for 10 minutes, get ABG before/after
PaO2 > 250 = lung
PaO2 < 100 = heart
List 5 causes of neonatal seizures
- HIE
- CNS infection
- Intracranial bleed
- Ischemic stroke
- Chromosomal abnormality
- Metabolic disturbance
* Hypoglycemia
* Hypocalcemia
* Hypomagnesemia
* Pyridoxine deficiency
* Inborn error of metabolism - Drug withdrawal
Explain the Gartland classification system
For extension-type supracondylar fractures:
- I = non-displaced fracture
- II = anterior cortex displaced
- III = anterior + posterior cortex displaced
What are the three phases of pertussis? How is it diagnosed? Treatment?
Phases
- Catarrhal phase - URTI
- Paroxysmal phase - cough, post-tussive emesis
- Convalescent phase - chronic cough
Diagnosis
- NP Swab for PCR or Cx
Treatment
- Azithromycin 10 mg/kg day 1, then 5 mg/kg on days 2-5
- Vaccine
- Public health
- Isolate
List 10 causes of acute renal failure in children
- Dehydration
- DKA
- Cardiogenic shock
- AIN
- RTA
- ATN
- Glomerulonephritis
- HUS
- TTP
- Pyelonephritis
- Posturethral valves
- Renal vein thrombosis
- Nephrolithiasis
- RCC
What nerve is at risk in flexion-type supracondylar fractures? Extension-type?
- Flexion = Ulnar
- Extension = AIN (Median)
List 5 x-ray findings consistent with epiglottitis.
- Thumbprint sign
- Thickened epiglottitis
- Thickened aryepiglottic folds
- Dilated hypopharynx
- Lack of air in the vallecula
List 8 differences between the adult and pediatric airway.
- Prominent occiput
- Large tongue
- Large tonsils
- Dynamic airway collapse w/ res
- Large, floppy epiglottis
- Anterior/Cephalad larynx
- Cricoid is narrowest
- Small airways
List 3 clinical clues that can help differentiate cardiac vs respiratory central cyanosis
- Response to hyperoxia test
- Response to crying
- Work of breathing
What is the ED management of SCFE? List 2 complications.
Treatment
- NWB (crutches or wheelchair)
Complications
- AVN
- Chondrolysis
- Non-union
- Growth arrest
- Arthritis
How do you differentiate SVT and sinus tachycardia in a baby?
SVT
- No precipitating event (fever, pain, etc.)
- No variability
- No response to fluids
- No p waves on ECG
- Rate >220
What is the risk of serious bacterial infection in a neonate (0-28 days)? What about 29-60 days?
- Neonate (0-28 days) - 10-20%
- Infant (29-60 days) - 10%
List 7 causes of phimosis in a child
- Physiologic
- Trauma
- Infection
- Chemical irritation
- Poor hygiene
- Congenital
- Circumcision
List 5 complications of supracondylar fracture.
- Vascular injury
- Nerve injury
- Compartment syndrome
- Volkmann’s contracture
- Gunstock deformity
Name 5 risk factors/Px findings that are associated with severe bronchiolitis.
- Underlying heart disease
- Underlying lung disease
- Prematurity
- RR >70
- SpO2 <95%
- Ill appearance
- Atelectasis on CXR
What makes a heart murmur more likely to be pathologic?
- Diastolic
- Any thrill
- Murmur with click/rub/gallop
- Weak pulse
- Cyanosis
- Respiratory distress
- ECG abnormality
- CXR w/ cardiomegaly
Outline an approach to a febrile neonate (0-28 days)
Workup
- CBC
- BCx
- UA + UCx
- LP
- CXR
- +/- Stool Cx
Treatment
- Ampicillin 50 mg/kg/dose
- Cefotaxime 50 mg/kg/dose
- +/- Acyclovir 20 mg/kg/dose if RF for HSV
What diagnosis must you consider in a boy with a left-sided varicocele? Right-sided?
- Left
- RCC with left renal vein occlusion
- Right
- IVC thrombosis/compression
Provide a DDx of 8 things for a child with wheeze
Infectious
- Croup
- Bronchiolitis
- Pneumonia
- Tuberculosis
- Bronchiolitis obliterans
Anatomy
- GERD
- CF
- CHF
- Tracheoesophageal fistula
- Mediastinal mass
- Vascular ring
Acquired
- Foreign body
- Anaphylaxis
Compare and contrast the various degrees of dehydration
Mild (<3%, 30 mL/kg)
- Alert
- Normal vitals
- Normal cap refill
Moderate (6%, 60 mL/kg)
- Irritable
- Maybe normal vitals
- Abnormal cap refill
Severe (9%, 90 mL/kg)
- Lethargic
- Hypotensive/Tachycardic
- No urine
List 5 central and 5 peripheral causes vertigo in children
Central
- AVM
- Meningitis
- Encephalitis
- CNS Abscess
- CNS Mass
- Migraine
- Trauma
Peripheral
- BPPV
- Benign Paroxysmal Vertigo of Childhood
- Cholesteatoma
- DM
- Labyrithinitis
- Lyme
- AOM
- Ototoxin
- Trauma
- Vestibular Neuritis
List and differentiate 4 types of diarrhea
Secretory
- Enterotoxin induced cAMP causing Cl and HCO3 secretion to lumen
Osmotic
- Poorly absorbed solutes draw water into lumen
Altered Motility
- Neurologically increased transit time
Dysentery
- Enteroinvasive bowel ischemia causing poor absorption
What is the treatment for infectious diarrhea?
- Azithromycin for most
- CTX for typhoid
- Doxy for cholera
- Vanco for C. diff
- Flagyl for protozoa
Fluoroquinolones are often 2nd line agents
List 5 low-risk criteria for bacterial meningitis
- Negative gram stain
- CSF protein <80 mg/dL (<0.5 g/L)
- CSF ANC <1000 cells/mL
- WBC <10
- No seizures
When and how much steroid is given in meningitis?
As per CPS: Within 4h of ABx (earlier = better)
Dexamethasone 0.15 mg/kg IV q6h
What does the IDSA recommend in regards to when to culture (6) stool in a traveler with diarrhea?
- Diarrhea 2+ weeks
- Bloody
- Mucoid
- Fever
- Severe abdominal pain
- Sepsis
When do you work up a jaundiced baby (5)?
- Jaundice at birth
- Fever
- Looks unwell
- Conjugated hyperbilirubinemia
- >3 weeks
- Not responding to phototherapy
- Rapidly rising bilirubin not explained by hx/pe
Name 6 lead points that can cause intussusception
- Lymphoma
- Meckel diverticulum
- IgA vasculitis (formerly called Henoch-Schönlein purpura or HSP)
- Mesenteric lymphadenitis
- Peyer’s patches
- Polyps
- Celiac disease
- CF
How does fetal circulation change at birth?
First gasp fills lungs with air, reducing hypoxic vasoconstriction
RV resistance drops and blood prefers RV over LV
With this shift, LA pressures increase and close the PFO
Increased oxygen causes PDA and PDV to close
What is the treatment of meningitis by age?
- 0-28 days
- 1-3 months
- 3+ months
0 - 28 days
- Dexamethasone 0.15 mg/kg
- Ampicillin 75 mg/kg
- Cefotaxime 75 mg/kg
- Gentamycin 3 mg/kg
1-3 months
- Dexamethasone 0.15 mg/kg
- Ceftriaxone 100 mg/kg
- Vancomycin 15 mg/kg
3+ months
- Dexamethasone 0.15 mg/kg
- Ceftriaxone 100 mg/kg
- Vancomycin 15 mg/kg
List 5 steps in the management of a child with a suspected inborn error of metabolism?
- ABCs
- NPO
- Critical Sample
- D5NS at 2x maintenance
- NaHCO3 if no resolution of acidosis
- Dialysis if necessary
- Ammunol if encephalopathic
Which diarrhea-causing bugs (4) do not require antibiotics?
- E. coli STEC
- Salmonella, non-typhoid
- Vibrio parahemolyticus
- Yersinia enterocolitica
List 5 indications for neuroimaging in children with headache
- Trauma
- Focal neuro deficits
- VP Shunt
- Morning headaches
- Meningimus
Outline the Philadelphia Criteria
- Age 29-60 days
- Temperature >38.2 degrees
- Well looking
- Labs
- WBC < 15
- Bands:Neutrophil < 0.2
- UA < 10 WBCs/hpf
- CSF < 8 WBCs/hpf
- CXR normal (if obtained)
- Stool negative (if obtained)
- Sens 98%
- NPV 99.7%
What is the DDx for the sick neonate?
THE MISFITS
- Trauma
- Heart, Hypovolemia, Hypoxia
- Endocrine (CAH)
- Metabolic
- Inborn Error of Metabolism
- Sepsis
- Formula
- Intestinal Catastrophe
- Toxin
- Seizure
List 8 risk factors associated with death from asthma
- Three ED visits in 12 months
- Two admissions in 12 months
- One ICU admission
- One ED/hospitalization in last month
- >2 MDIs in the last month
- Current use/withdrawal from systemic steroids
- Difficulty perceiving symptoms
- Low SES
- Illicit drug use
- Psychosocial problems
- Chronic heart disease
- Chronic lung disease
- Chronic psychiatric illness
What is the DDx of a crying infant?
IT CRIES
- Infections
- Trauma, Torsion
- Cardiac
- Reflux
- Intestinal Catastrophe
- Eye
- Strangulation
Describe the ossification centers around the elbow.
CRITOE
- 1 - Capitellum
- 3 - Radial head
- 5 - Internal (medial) epicondyle
- 7 - Trochlea
- 9 - Olecranon
- 11 - External (lateral) epicondyle
What are 4 x-ray findings in SCFE?
- Blurring of the metaphyseal-growth plate junction
- Blanch sign of steel
- Klein’s line doesn’t intersect lateral femoral head
- Enlarged angle of Southwick
What return instructions do you give for children with diarrhea?
- V/D worsens
- Vomiting >24h
- Bloody vomit/stool
- Decreased U/O
A 4yo boy presents with seizure and a sodium of 110 mEq/L.
Calculate how much 3% saline to get his sodium to 125 mEq/L
Amount Na = (0.6 x weight) x (desired Na - measure Na)
Weight = 10 + (Age x 2) = 18
(0.6 x 18) x (125 - 110)
10.8 x 15 = 162 mEq Na
513 mEq/L of 3% saline
(162 / 513) x 1000 cc = ~320 cc
Give 2 cc/kg q10min until seizure stops
What is the treatment for Kawasaki disease?
- IVIG 2 g/kg IV over 2 hours
- ASA 20-25 mg/kg q6h
- Steroids in refractory cases
What are the Rule of 2’s in a Meckel’s?
- 2 cm wide
- 2 cm long
- 2 ft from the ileocecal valve
- 2% of the population
- 2% symptomatic
- ½ present by age 2, most age 20
What are the 5 diagnostic criteria for a febrile seizure?
What 4 things define simple vs. complex?
- Seizure + Fever with no other cause
- Etiology = rapid rise in fever
-
Dx:
1. Age 6 mo - 6 yr
2. Fever >38 degrees
3. No CNS infection
4. No acute metabolic abnormality
5. No previous afebrile seizures -
Simple:
1. <15 mins
2. 1 per 24 h
3. GTC
4. Neurologically normal
List 7 complications of circumcision
- Bleeding
- Infection
- UTI
- Urethral meatus stenosis
- Phimosis
- Skin bridges
- Inclusion cysts
List 10 causes of hip pain in children
- AVN
- Reiters
- Septic joint
- Juvenile arthritis
- Osteomyelitis
- Fracture
- Abuse
- SCFE
- Ewing’s sarcoma
- Sickle cell
What is the workup for a jaundiced baby?
- CBC w/ smear
- Bili - direct and indirect
- Haptoglobin
- LDH
- TSH
- BCx
- G6PD assay
- Coomb’s test
- U/S abdomen
List 10 causes of hematuria in a child
- Trauma
- UTI
- Pyelonephritis
- Renal colic
- RCC
- Nephritic syndrome
- AIN
- ATN
- PCKD
- HSP
- SLE
- SS
- Mono
- Hemophilia
- Munchausen’s
Which diarrhea-causing bugs (9) require antibiotics?
- Campylobacter
- Clostridium difficile
- Cryptosporidium
- E. coli ETEC
- Entamoeba histolytica
- Salmonella typhi
- Shigella
- Vibrio cholerae
- Giardia
Provide two formulas to estimate the weight of an infant/child
- Neonate (0-12m): Weight (kg) = 4 + (Months / 2)
- Child (1-12y): Weight (kg) = 10 + (Age x 2)
Name four possible x-ray findings in intussusception
- Target sign - air in intussusceptum
- Meniscus sign - air compresses from invaginating bowel
- Crescent sign - lucency in LUQ soft tissue mass
- Free air
List 6 admission criteria for croup.
- Hypoxemia
- Significant work of breathing
- Tachycardia/Tachypnea
- Stridor at rest after treatment
- Complex PMHx
- Dehydration
What is a BRUE? List 4 diagnostic criteria.
Event occurring in an infant <1 year with a sudden, brief, resolved episode with at least one of:
- Change in colour
- Change in breathing
- Change in tone
- Altered LOC
List 5 criteria to define a LOW RISK BRUE.
- Age > 2 months
- Born >32 weeks + Corrected age >45 weeks
- No CPR by a medical person
- Lasted <1 minute
- First event
List 8 DDx for BRUE
- Choking/Gagging
- Periodic breathing
- Breath-holding
- Respiratory infection (pertussis, RSV)
- Sepsis
- Intestinal catastrophe
- Inborn error of metabolism
- Endocrine
- Abuse
- GERD
- Arrhythmia
- Cardiomyopathy
- Seizure
- Syncope
THE MISFITS
What is the #1 cause of death in infants 1 mo - 1 yr old?
SIDS
Unknown cause of death after thorough investigation/autopsy
List 10 risk factors for SIDS
Baby
- Premature
- Prone
- Pillows
- Puny (Low birth weight)
- Penis (Male)
- Age 1 - 6 months
Maternal
- Late/no pre-natal care
- Smoking during pregnancy
- <20 years old
Environment
- Second-hand smoke
- Born fall/winter
- Overheating
- Bed-sharing
List 8 AAP recommendations to prevent SIDS
- Sleep supine
- Firm sleeping surface
- No pillows
- No co-sleeping
- No smoking
- No overheating
- Pacifier at bedtime
- Breastfeed
- Sleep in crib in parents room to 6 months
- Prone while awake to prevent plagiocephaly