viral hemorrhagic and prion

Question 1

what is virus hemorrhagic fever

Answer 1

Virus that can cause massive hemorrhaging

-no cure only supportive care

Question 2

where most deadly hemorrhage fevers found

Answer 2

Africa

Question 3

what is viral hemorrhagic fever caused by

Answer 3

filovirus – long filaments

Question 4

zaire

Answer 4

-most deadly of all ebola

Question 5

sudan

Answer 5

2nd most deadly in humans

Question 6

reston virus

Answer 6

-known to be deadly in primates other than humans

Question 7

where was Ebola found

Answer 7

Zaire region in Africa now known as the Congo

Question 8

what primates can become infected with human deadly forms of ebola

Answer 8

monkeys, gorillas, chimps

-dead end host

Question 9

what is thought to be primary reservoir of ebola

Answer 9

fruit bat

Question 10

viral hemo transmission

Answer 10

human to human
-blood, body fluids, and semen
-mother to baby
-contaminated medical equipment
-meat of contaminated animals

Question 11

in viral hemorragic disease how long can semen be infected

Answer 11

up to a year after infection

-once someone dies body fluids still infected

Question 12

viral hemorrhagic disease incubation period

Answer 12

short, within a few days to a week after infection will start to be symptomatic

-no transmission until symptoms are seen

Question 13

viral hemorrhagic symptoms

Answer 13

fever, headache, muscle and stomach pain, vomiting and diarrhea, and bleeding

Question 14

mortality rate of ebola can reach what percent

Answer 14

90%

-depending on the type

Question 15

what animal can be infected with several forms of ebola

Answer 15

pigs

-can pass the deadly forms to humans

Question 16

vaccine for ebola

Answer 16

Merck

-pushback from people in africa due to western medicine

Question 17

diagnosis of viral hem

Answer 17

Can either be done via ELISA looking for antibodies or PCR testing

Question 18

marburg virus

Answer 18

-similar to ebola, genetically different
-found in marburg germany with people who travel to Africa and came home sick

Question 19

primary reservoir for marburg virus

Answer 19

fruit bats

Question 20

difference from ebola and marburg virus

Answer 20

rash seen in marburg

Question 21

who is susceptible to Marburg virus

Answer 21

hospital workers

-high transmission

Question 22

prion disease classified as

Answer 22

slow virus disease
-misshaped protein

takes years to cause symptoms

-once symptomatic become fatal

Question 23

where does prion disease come from

Answer 23

transmitted, inherited, and come from unknown sources

Question 24

what does prion disease cause

Answer 24

spongiform encephalitis
-brain spongey in autopsy

-affects man and animals

Question 25

most well known prion disease of animal forms

Answer 25

scrapie -seen in sheeps and goats -affects brain, neurological changes -want to scrap off wool

Question 26

what age animals does scrapie affect

Answer 26

2-5

Question 27

what happens to animal if have scrapie

Answer 27

need to kill entire herd if one animal has it, burn the ground and not used

Question 28

scrapie affect humans?

Answer 28

no

Question 29

kuru

Answer 29

seen in fore people in papa new guinea -seen from cannibalism trembling or shaking

Question 30

creutzfeldt-jakob disease is similar to what

Answer 30

Alzheimer's -- symptoms CJD symptoms are rapid tho and will die within year of having -people above 60 get

Question 31

sporadic form

Answer 31

-most cases of CJD -comes on and can't trace to anything

Question 32

familial form

Answer 32

○ If family member has you have increased risk of getting ○ Dominant inheritance

Question 33

acquired form due to

Answer 33

-contaminated medical equipment -pituitary growth hormone- PERMEANT DEFERRAL FOR BLOOD -vCJD

Question 34

what is variant CJD traced to

Answer 34

contaminated beef aka mad cow disease -lower age onset -slow -people in certain parts of europe deferred from donating for life -no meat from Europe

Question 35

wasting disease seen in

Answer 35

deer, elk no evidence of passing prion to human -warn hunters to not kill animals being weird -seen in US