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GI - Week 2 > Viral hepatitis > Flashcards

Viral hepatitis Flashcards

(52 cards)

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1
Q

Hepatitis A belongs to this viral family

A

Picornavirus

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2
Q

This hepatitis virus belongs to the Picornavirus family

A

Hepatitis A

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3
Q

What is the route of transmission for Hepatitis A?

A

Fecal-oral
epidemics frequent

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4
Q

Do most cases of Hepatitis A resolve?

A

Yes - almost always a self-limited infection

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5
Q

Is there chronic Hepatitis A?

A

No

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6
Q

Rash, leukocytoclastic vasculitis, arthralgias, and glomerulonephritis are extrahepatic symptoms of these two hepatitis viruses

A

Hepatitis A and B

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7
Q

This is used to diagnose active infection with Hepatitis A

A

IgM

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8
Q

Hepatitis B belongs to this viral family

A

Hepadnavirus

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9
Q

This hepatitis virus belongs to the Hepadnavirus family

A

Hepatitis B

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10
Q

This hepatitis virus is considered highly infectious

A

Hepatitis B

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11
Q

This hepatitis virus is the most common cause of chronic liver disease and hepatocellular carcinoma

A

Hepatitis B

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12
Q

This hepatitis virus is an endemic in SE Asia, China, Africa

A

Hepatitis B

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13
Q

Perinatal transmission may occur with these two hepatitis viruses

A

Hepatitis B and C

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14
Q

Is there chronic Hepatitis B?

A

Yes - is age dependent (95% of perinatal infections become chronic)

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15
Q

Is perinatal infection or adult infection with Hepatitis B more likely to become chronic?

A

Perinatal
95% become chronic

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16
Q

Are most cases of Hepatitis B asymptomatic?

A

Yes (70%)

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17
Q

25% of patients with chronic hepatitis with this virus develop cirrhosis with risk of hepatocellular carcinoma

A

Hepatitis B

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18
Q

This serologic marker for Hepatitis B indicates transmissible infection

A

sAg (surface Ag)

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19
Q

This serologic marker for Hepatitis B is best for acute infection (window period)

A

IgM anti HepBc (core Ag)

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20
Q

This serologic marker for Hepatitis B indicates immunity

A

Anti-sAg

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21
Q

This serologic marker for Hepatitis B increases with increasing transmissibility

22
Q

This serologic marker for Hepatitis B correlates with decreased viremia/transmission

23
Q

In Hepatitis B serology, sAg indicates this

Study These Flashcards
A

Transmissible infection

24
Q

In Hepatitis B serology, IgM anti HepBc indicates this

Study These Flashcards
A

Acute infection (window period)

25
In Hepatitis B serology, anti-sAg indicates this
Immunity
26
In Hepatitis B serology, eAg indicates this
Transmissibility (increases with increasing transmissibility)
27
In Hepatitis B serology, eAb indicates this
Correlates with decreased viremia/transmission
28
This test is used to assess treatment or risk of progression of hepatitis B
DNA PCR
29
Hepatitis C belong to this viral family
Flavivirus
30
This hepatitis virus belongs to the flavivirus family
Hepatitis C
31
Transmission of Hepatitis C is this
Parenteral (IV drug use, occupation exposure, transfusion, partuition, sexual)
32
This is the most common cause of chronic viral hepatitis
Hepatitis C
33
Is there chronic infection with Hepatitis C?
Yes - most infections become chronic and persistent
34
Do acute infections with Hepatitis C cause severe disease?
No
35
In Hepatitis C with recovery, is PCR positive or negative?
Negative
36
Is Hepatitis C PCR positive in chronic infection?
Yes - remains positive
37
In Hepatitis C, disease activity tends to fluctuate, and correlates with this
AST/ALT
38
Life cycle of this hepatitis virus depends on HepB presence
Hepatitis D
39
Life cycle of Hepatitis D depends on the presence of this
HepB
40
Transmission of Hepatitis D is this
Parenteral
41
This hepatitis virus is enterically transmitted and zoonotic
Hepatitis E
42
Infection with this hepatitis virus is associated with travel to Asia, India, Africa Infection is self-limited
Hepatitis E
43
Is there chronic Hepatitis E infection?
No
44
Hepatitis E has risk of fulminant hepatitis in this patient population
Pregnant women
45
The average incubation period of Hepatitis E is this many days
40 days
46
Does Hepatitis E illness severity increase or decrease with age?
Increases
47
Is there portal lymphocyte inflammation in viral hepatitis?
Yes (extension into limiting plate = interface hepatitis)
48
Are acidophil bodies and Kupffer cell clusters seen in viral hepatitis?
Yes
49
Morphology of this hepatitis virus has classic micronodular cirrhosis
Hepatitis C
50
Does HepC antibodies or PCR show exposure?
Antibodies
51
Does HepC antibodies or PCR show presence of virus?
PCR
52
These three hepatitis viruses can have chronic infections
B, C, D

GI - Week 2 (12 decks)

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