Viral Hepititis

Question 1

Symptoms of acute viral hepatitis

Answer 1

jaundice, dark urine, acholic stool, prodome

Question 2

Definition of chronic viral hepatitis

Answer 2

hepatitis that doesn’t resolve within 6 months

Question 3

What does chronic viral hepatitis predispose you to

Answer 3

hepatocellular carcinoma

cirrhosis

Question 4

What can fulminant viral hepatitis cause

Answer 4

massive hepatic necrosis
encephalopathy
edema

Question 5

What are some complications for fulminant viral hepatitis

Answer 5

cerebral edema
brainstem compression
GI bleeding
sepsis
organ failure

Question 6

What is the treatment for fulminant viral hepitis

Answer 6

liver transplant

Question 7

Virus family of hepatitis A

Answer 7

picornavirus

Question 8

Transmission of hepatitis A

Answer 8

fecal-oral

Question 9

Is hepatitis A chronic

Answer 9

no

Question 10

Virus family of hepatitis B

Answer 10

hepadnavirus

Question 11

What is the transmissino of Hepatitis B

Answer 11

body fluids

Question 12

Is hep B chronic

Answer 12

yes

Question 13

VIrus family of hep C

Answer 13

flavivirus

Question 14

What is the transmission of hep C

Answer 14

body fluids

Question 15

Is hep C chronic

Answer 15

yes

Question 16

What is the virus family of hep D

Answer 16

deltavirus

Question 17

What is the tranmission of Hep D

Answer 17

body fluids

Question 18

Is hep D chronic

Answer 18

yes

Question 19

VIrus family of Hep E

Answer 19

hepevirus

Question 20

Transmission of hep E

Answer 20

fecal-oral

Question 21

Is hep E chronic

Answer 21

no

Question 22

Genome of Hep A

Answer 22

+ssRNA

Question 23

How do you diagnose Hep A

Answer 23

IgM antibodies against HAV

Question 24

Hep A vax

Answer 24

inactivated

IM injection w/ 2 doses

Question 25

What do you see when looking at Hep B under microscope

Answer 25

tubes & spheres | Dana particles

Question 26

tubes and sphere

Answer 26

incomplete, noninfectious particles | surround the dane particles and can be used for detection

Question 27

Dan particles

Answer 27

complete virions | infectious

Question 28

genome of Hep B

Answer 28

dsDNA

Question 29

_______ is part of the life cycle of hep B

Answer 29

reverse transcription

Question 30

What do you see in a pt acutely infected w/ Hep B

Answer 30

+ HBsAG + anti-HBc total + IgM

Question 31

What do you see in a pt chronically infected with hep B

Answer 31

+ HBsAg | + anti-HBc total

Question 32

What do you see if a pt vaccinated against hep B

Answer 32

+ anti-HBsAg

Question 33

What do you see in a pt previously affected w/ hep B

Answer 33

+ anti-HBsAg | + total anti-HBc

Question 34

What is unique about the risk for infection with those with hep B

Answer 34

it's coorelated with age - the younger you are, the more likely you are to be infected

Question 35

How do you treat chronic Hep B

Answer 35

lamivvudine or famcylovir/adeforvir dipivoxil AND interferon-alpha

Question 36

What is in the Hep B vax

Answer 36

purified HBsAg protein. Produced in yeast | IM injection of 3 doses

Question 37

Genome of Hep C

Answer 37

+ssRNA

Question 38

Is hep C enveloped?

Answer 38

yes

Question 39

Common ways hep C is spread

Answer 39

IV drug use | tattoos

Question 40

Screening test for hep C

Answer 40

antibody-based test for anti-HCV antibodies

Question 41

Confirmatory test for Hep C

Answer 41

PCR

Question 42

How do symptoms of Hep C compare to A and B

Answer 42

more mild acute symptoms

Question 43

sofosbuvir

Answer 43

RNA dependent RNA inhibitor that is used to treat chronic Hep C

Question 44

genome of hep D

Answer 44

small circular ssRNA

Question 45

What does Hep D encode

Answer 45

2 proteins (delta short and delta long antigens) that cover the virious

Question 46

Who does Hep D infect

Answer 46

ONLY those who have been previously or concurrently infected with Hep B

Question 47

Relationship between Hep D and fulminant hepatitis

Answer 47

more likely outcome

Question 48

How does Hep D damage the body

Answer 48

directly injures hepatocytes

Question 49

How do you diagnose Hep D

Answer 49

ELISA

Question 50

Genome of Hep E

Answer 50

+ssRNA

Question 51

Hep E is associated with what

Answer 51

travel

Question 52

Why does Hep E have a high risk of death

Answer 52

infection in pregnant women