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Micro Exam III > Viral Infections of GI Tract II > Flashcards

Viral Infections of GI Tract II Flashcards

1
Q

What genome family is the polio virus from

A

picornaviridae (RNA)

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2
Q

Poliovirus virions stable at _______

A

acidic pH

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3
Q

What are the serotypes of poliovirus

A

P1, P2, P3

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4
Q

How is poliovirus transmitted

A

fecal-oral

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5
Q

What is the incubation period for poliovirus

A

6 to 20 days

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6
Q

Where is the poliovirus currently endemic

A

Afghanistan
Nigeria
Pakistan

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7
Q

What are the clinical manifestations of poliovirus

A

asymptomatic
abortive poliomyelitis
nonparalytic aseptic meningitis
flaccid paralysis

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8
Q

Symptoms for abortive poliomyelitis

A

sore throat
fever, vomiting, constipation
NO paralysis

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9
Q

Symptoms for nonparalytic aseptic meningitis

A

nonspecific prodromal symptoms
stiffness is back, neck, or legs
lasts for 2 to 10 days

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10
Q

How can you diagnose poliovirus

A

can be isolated from stool of patients

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11
Q

What was a potential risk of the trivalent, live attenuated oral polio vaccine

A

VAPP

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12
Q

Symptoms of viral gastroenteritis

A

inflammation of stomach and intestines, nausea, diarrhea, vomiting

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13
Q

How is viral gastroenteritis spread

A

fecal oral

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14
Q

Is viral gastroenteritis enveloped

A

no

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15
Q

What are the types of viral gastroenteritis

A

rotavirus, norovirus, adenovirus, astrovirus

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16
Q

What are the major differences between viral and bacterial gastroenteritis

A

viral has a longer incubation period, prominent vomiting, and nonbloody stool

17
Q

Signs of severe dehyrdation

A

rapid, weak pulse, sunken eyes, tears absent, skin tenting, lack of urination

18
Q

Who does rotavirus most commonly affect

A

young kids

19
Q

What is unique about the rotavirus

A

it has a segmented genome, which remains in the core particle during infection

20
Q

Is rotairus a major opportunistic pathogen in HIV infections?

A

NOPE

21
Q

When is rotavirus season?

A

later winter/early spring

22
Q

Rotavirus produces a toxin _____ that causes _____ release

A

NSP4

Ca++

23
Q

How do you diagnose rotavirus

A

EIA from stool sample

24
Q

How do you treat viral gastroentritis

A

oral rehydration for mild

IV rehdration for severe

25
Q

How is Rotavirus prevented

A

handwashing, sanitization
IgA in colostrum
vaccine

26
Q

What are the rotavirus vaccines

A

2 live attenuated oral vaccines.

27
Q

What genome family is norvirus from?

A

caliciviridae

+ssRNA

28
Q

How can norovirus be spread?

A 
person to person contact
vomit droplets
fomites
waterborne
food contamination
29
Q

What type of genome is adenovirus

A

dsDNA

30
Q

What adenovirus serotypes cause gastroenteritis

A

40 and 41

31
Q

Does adenovirus have seasonal variation

A

nope

32
Q

How do you diagnose adenovirus

A

antibody based

33
Q

What type of genome is astrovirus

A

+ssRNA

Micro Exam III (9 decks)

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