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Respiratory II > Viral URIs > Flashcards

Viral URIs Flashcards

1
Q

Enveloped DNA virus that targets CD21 receptor on B cells

A

EBV

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2
Q

IgG and absence of EBNA in EBV

A

Chronic primary infection

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3
Q

IgM for EBV

A

Acute primary infection

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4
Q

IgG and EBNA for EBV

A

Past infection

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5
Q

Treatment for EBV

A

Antipyretics
Refrain from contact sports

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6
Q

Complications of EBV

A

Splenic rupture
Latency

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7
Q

Enveloped DNA virus that remains latent in ganglion

A

HSV

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8
Q

Complications of HSV in immunocompromised

A

Dissemination
Herpes encephalitis

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9
Q

Pt presents with vesicular lesion on around the mouth, ulcerative lesions with grayish exudate on the oral mucosa and pharynx, erythema of pharynx with whitish exudate, and lymphadenopathy

A

HSV

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10
Q

Stain used for seeing multinucleated giant cells in HSV

A

Tzanck smear

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11
Q

Treatments for HSV

A

Acyclovir
Nucleoside analog

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12
Q

Some possible CMV presentations in immunocompromised

A

CMV hepatitis
CMV retinitis
Interstitial pneumonia

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13
Q

Characteristic histology finding in CMV

A

Owl’s eye inclusion body

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14
Q

Morphology of HSV

A

Enveloped dsDNA virus

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15
Q

Pt presents with erythematous pharynx with exudate, non-purulent conjunctivitis, and mild blanching rash on cheeks and torso. They swim regularly at a public pool.

A

Adenovirus - pharyngoconjunctival fever

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16
Q

Complications of adenovirus in immunocompromised

A

Serious pneumonia
Hepatitis

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17
Q

Infections that can be caused by adenovirus

A

Pharyngoconjunctival fever
Acute respiratory distress
Epidemic keratoconjunctivitis
Diarrhea
Cystisis

18
Q

Icosahedral non-enveloped DNA virus that targets the mucosal epithelium of the respiratory tract and conjunctiva

A

Adenovirus

19
Q

In which part of the cell does adenovirus replicate?

A

Within the nucleus

20
Q

Non-enveloped RNA virus that presents as shallow yellow ulcers surrounded by red halos in the oral mucosa

A

Coxsackie A

21
Q

Child presents with thick-walled gray vesicles on an erythematous base on the palmar and plantar surfaces of the hands, on the face, and on the buttocks

A

Coxsackie A

22
Q

Herpangina

A

Coxsackie A only with ulcers in the mouth

23
Q

Medication contraindicated in Coxsackie A

A

Steroid

24
Q

Uncommon causes of pharyngitis

A

HIV
Toxoplasma
Mycoplasma pneumoniae
Gonococcal

25
Q

Complications of otitis media

A

Ruptured TM
Chronic suppurative otitis media
Mastoiditis

26
Q

Treatments for otitis media

A

Amoxicillin
3rd gen cephalosporin

27
Q

Small, pleomorphic, gram-negative, coccobacillary rods with fastidious growth requirements

A

H influenzae

28
Q

Requirements for growth of H influenzae

A

X/hemin and V/NAD –> chocolate agar

29
Q

How will H influenzae grow on blood agar?

A

If in the presence of S aureus, X and V
Satellitism

30
Q

Risk factors for malignant otitis externa

A

DM
Immunocompromised elderly

31
Q

Severe necrotizing infection that spreads from squamous epithelium of ear canal to adjacent areas of soft tissue, blood vessels, cartilage, and bone

A

Malignant otitis externa

32
Q

Life threatening complication of malignant otitis externa

A

Spread to temporal bone, sigmoid sinus, or base of skull

33
Q

Treatment for otitis externa

A

Debridement
Ear drops –> fluoroquinolone, neomycin, hydrocortisone

34
Q

Treatment for malignant otitis externa

A

Ceftazidime or cefepime
Piperacillin + aminoglycoside
Fluoroquinolone
Carbapenem

35
Q

Gram negative diplococci without a capsule. Grows well on blood agar. Produces beta lactamase

A

Moraxella catarrhalis

36
Q

Possible infections caused by Moraxella catarrhalis

A

Otitis media
Sinusitis
COPD exacerbations

37
Q

Non-enveloped, positive sense, ssRNA virus that has optimum replication of 32 C

A

Rhinovirus

38
Q

How does rhinovirus attach to nasal or pharyngeal epithelium?

A

ICAM-1

39
Q

Inflammatory factors that cause hyperemia and edema in rhinovirus infection

A

IFN-alpha and IFN-beta

40
Q

Complications of a cold

A

Sinusitis
Otitis media
Tracheobronchitis

Respiratory II (17 decks)

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