Viral URIs

Question 1

Enveloped DNA virus that targets CD21 receptor on B cells

Answer 1

EBV

Question 2

IgG and absence of EBNA in EBV

Answer 2

Chronic primary infection

Question 3

IgM for EBV

Answer 3

Acute primary infection

Question 4

IgG and EBNA for EBV

Answer 4

Past infection

Question 5

Treatment for EBV

Answer 5

Antipyretics
Refrain from contact sports

Question 6

Complications of EBV

Answer 6

Splenic rupture
Latency

Question 7

Enveloped DNA virus that remains latent in ganglion

Answer 7

HSV

Question 8

Complications of HSV in immunocompromised

Answer 8

Dissemination
Herpes encephalitis

Question 9

Pt presents with vesicular lesion on around the mouth, ulcerative lesions with grayish exudate on the oral mucosa and pharynx, erythema of pharynx with whitish exudate, and lymphadenopathy

Answer 9

HSV

Question 10

Stain used for seeing multinucleated giant cells in HSV

Answer 10

Tzanck smear

Question 11

Treatments for HSV

Answer 11

Acyclovir
Nucleoside analog

Question 12

Some possible CMV presentations in immunocompromised

Answer 12

CMV hepatitis
CMV retinitis
Interstitial pneumonia

Question 13

Characteristic histology finding in CMV

Answer 13

Owl’s eye inclusion body

Question 14

Morphology of HSV

Answer 14

Enveloped dsDNA virus

Question 15

Pt presents with erythematous pharynx with exudate, non-purulent conjunctivitis, and mild blanching rash on cheeks and torso. They swim regularly at a public pool.

Answer 15

Adenovirus - pharyngoconjunctival fever

Question 16

Complications of adenovirus in immunocompromised

Answer 16

Serious pneumonia
Hepatitis

Question 17

Infections that can be caused by adenovirus

Answer 17

Pharyngoconjunctival fever
Acute respiratory distress
Epidemic keratoconjunctivitis
Diarrhea
Cystisis

Question 18

Icosahedral non-enveloped DNA virus that targets the mucosal epithelium of the respiratory tract and conjunctiva

Answer 18

Adenovirus

Question 19

In which part of the cell does adenovirus replicate?

Answer 19

Within the nucleus

Question 20

Non-enveloped RNA virus that presents as shallow yellow ulcers surrounded by red halos in the oral mucosa

Answer 20

Coxsackie A

Question 21

Child presents with thick-walled gray vesicles on an erythematous base on the palmar and plantar surfaces of the hands, on the face, and on the buttocks

Answer 21

Coxsackie A

Question 22

Herpangina

Answer 22

Coxsackie A only with ulcers in the mouth

Question 23

Medication contraindicated in Coxsackie A

Answer 23

Steroid

Question 24

Uncommon causes of pharyngitis

Answer 24

HIV
Toxoplasma
Mycoplasma pneumoniae
Gonococcal

Question 25

Complications of otitis media

Answer 25

Ruptured TM Chronic suppurative otitis media Mastoiditis

Question 26

Treatments for otitis media

Answer 26

Amoxicillin 3rd gen cephalosporin

Question 27

Small, pleomorphic, gram-negative, coccobacillary rods with fastidious growth requirements

Answer 27

H influenzae

Question 28

Requirements for growth of H influenzae

Answer 28

X/hemin and V/NAD --> chocolate agar

Question 29

How will H influenzae grow on blood agar?

Answer 29

If in the presence of S aureus, X and V Satellitism

Question 30

Risk factors for malignant otitis externa

Answer 30

DM Immunocompromised elderly

Question 31

Severe necrotizing infection that spreads from squamous epithelium of ear canal to adjacent areas of soft tissue, blood vessels, cartilage, and bone

Answer 31

Malignant otitis externa

Question 32

Life threatening complication of malignant otitis externa

Answer 32

Spread to temporal bone, sigmoid sinus, or base of skull

Question 33

Treatment for otitis externa

Answer 33

Debridement Ear drops --> fluoroquinolone, neomycin, hydrocortisone

Question 34

Treatment for malignant otitis externa

Answer 34

Ceftazidime or cefepime Piperacillin + aminoglycoside Fluoroquinolone Carbapenem

Question 35

Gram negative diplococci without a capsule. Grows well on blood agar. Produces beta lactamase

Answer 35

Moraxella catarrhalis

Question 36

Possible infections caused by Moraxella catarrhalis

Answer 36

Otitis media Sinusitis COPD exacerbations

Question 37

Non-enveloped, positive sense, ssRNA virus that has optimum replication of 32 C

Answer 37

Rhinovirus

Question 38

How does rhinovirus attach to nasal or pharyngeal epithelium?

Answer 38

ICAM-1

Question 39

Inflammatory factors that cause hyperemia and edema in rhinovirus infection

Answer 39

IFN-alpha and IFN-beta

Question 40

Complications of a cold

Answer 40

Sinusitis Otitis media Tracheobronchitis