virology 1

Question 1

pathogenesis of viral disease

Answer 1

1. direct invasion of the placenta
2. invasion of the placenta to the fetus
3. disease in the dam that directly affects fetus

Question 2

viral dz’s in cattle

Answer 2

bovine herpes
bvdv
schamallenberg

Question 3

bovine herpes 1 is spread by __ contact and abortion is most common @__ months of gestation with a __% abortion rate

Answer 3

nose to nose, 4 months, 5-60%

Question 4

hallmark lesion of bovine herpes 1

Answer 4

multifocal hepatic necrosis in the fetus with intranuclear inclusions

Question 5

BVDV has __ transmission with two strains: cytopathic strain have __ of an effect than noncytopathic

Answer 5

oronasal, less

Question 6

BVDV has a __ rate of abortion and __ pregnancy rate with multiple outcomes including __, __, __, __, __.

Answer 6

low, low, cerebellar hypoplasia, absorption, mummy, PI animals (25-150d), antibodies

Question 7

schmallenberg virus is spread by __

Answer 7

culicoides spp

Question 8

schmallenberg in the summer is characterized by __ while dec-january is characterized by __

Answer 8

diarrhea, fever, decreased milk

still births, congenital abnormalities

Question 9

horses with herpes __ look sick and will abort while horses with EVA __ look sick and abort

Answer 9

won’t, will

Question 10

Equine herpes virus is spread by __ contact and is infectious in __ stages of gestation with abortion the most common in the __ trimester

Answer 10

nose to nose, all, 3rd

Question 11

equine herpes virus has __ hepatic necrosis in the __ with __ inclusions

Answer 11

multifocal, fetus, intranuclear

Question 12

EHV-1 has __ while EHV-4 has __

Answer 12

stillbirths, sporadic abortions

Question 13

what is the hallmark of equine viral arteritis?

Answer 13

EDEMA!!!

mares limbs and mammary tissue
stallions sheath and scrotum

Question 14

EVA is spread by __ contact, __ or semen causing __

Answer 14

direct, transplacental, vasculitis

Question 15

on necropsy what would you see in a foal with EVA?

Answer 15

arteritis in the fetal heart or placenta

Question 16

border dz is like __ and is __ transmitted with abortion at __ stage resulting in __ and __

Answer 16

bvdv, venereally, any, cerebellar hypoplasia, hair instead of wool

hairy shakers dz

Question 17

bluetongue virus is spread by __ effecting what species?

Answer 17

culicoides, sheep, cattle, goats, wild ruminants, deer!

Question 18

bluetongue virus effects the __ cells resulting in __ and __

Answer 18

vascular endothelial, hemorrhage and edema

Question 19

what 2 viral diseases are spread by culicoides?

Answer 19

schmallenberg (cattle)
bluetongue (mostly small ruminants)

Question 20

t/f: its ok to give a pregnant animal the modified live vaccine for bluetongue virus

Answer 20

F

Question 21

a sheep presents with the following CS. what do you suspect?

Answer 21

fever
depression
cyanosis of tongue
blood vessel congestion on lips +muzzle
edema
abortion less common
inflammation of coronary band

Question 22

cache valley virus <32 days infx

Answer 22

early embryonic death

Question 23

cache virus infx 32-37 days

Answer 23

ms or cerebellar malformation

Question 24

cache virus 37-48d

Answer 24

musculoskeletal

Question 25

lesions of cache virus

Answer 25

• hydrocephalus + hydranencephaly
• cerebellar hypoplasia
• scoliosis