Virology

Question 1

Short term storage temperature for viruses (3 days)

Answer 1

4C

Question 2

Long-term storage temperature for viruses (4 days or longer)

Answer 2

-70C

Question 3

Mature virus containing NUCLEIC ACID CORE with protein coat, with or without envelope

Answer 3

Virion

Question 4

Viruses are charcterized by the presence of

Answer 4

DNA or RNA

Question 5

Largest DNA virus

Answer 5

Poxvirus

Question 6

Largest RNA virus

Answer 6

Paramyxovirus

Question 7

Smallest DNA virus

Answer 7

Parvovirus

Question 8

Smallest RNA virus

Answer 8

Picornaviridae (Enterovirus)

Question 9

All DNA viruses are icosahedral except

Answer 9

Poxvirus

Question 10

First step in the replication cycle of a virus

Answer 10

Attachment & replication

Question 11

Where is the site of virion assembly

Answer 11

Nucleus or cytoplasm

Question 12

Calcium alginate is TOXIC to N. gonorrhoeae and viruses because it could inactivate _____

Answer 12

HSV (Herpes Simplex Virus)

Question 13

The swab used for collecting samples for detecting viruses should be made from

Answer 13

Dacron or rayon

Question 14

Latency site of Varicella Zoster Virus

Answer 14

Dorsal root of ganglia

Question 15

Tzanck smear is used to detect

Answer 15

HSV and VZV

Question 16

Patient has chronic fatigue syndrome but negative for Streptococcus, EBV, and hepatitis. Test for

Answer 16

CMV (Cytomegalovirus)

Question 17

CMV isolation is best accomplished using

Answer 17

Human embryonic fibroblasts

Question 18

Cross-reactive in all human adenoviruses

Answer 18

Hexon

Question 19

Eosinophilic cytoplasmic inclusions are elementary bodies of

Answer 19

Poxvirus

Question 20

Reverse transcriptase is found in what type of virus

Answer 20

Retrovirus

Question 21

Specimen (s) collected from a patient with suspected enteroviral meningitis

Answer 21

Stool
Throat swab
CSF
Serum

Question 22

Enteroviruses can be differentiated from rhinoviruses by

Answer 22

Acid resistance

Question 23

Gold standard for rabies diagnosis

Answer 23

Direct fluorescent antibody test

Question 24

Myxoviridae virus envelope contains

Answer 24

Hemagglutinin & neuraminidase

Question 25

Test for influenza virus

Answer 25

Hemagglutination-inhibition

Question 26

Enteric Cytopathic Human Orphan virus is also known as

Answer 26

Echovirus

Question 27

Specimen of choice for detecting rotavirus

Answer 27

Stool

Question 28

What is used to collect a liquid stool sample in infants

Answer 28

Disposable diaper

Question 29

Stool sample is submitted for RSV detection. What should you do?

Answer 29

Reject the sample. RSV = Respiratory Synctial Virus

Question 30

Virus associated with bleeding disorder following bite from an Aedes mosquito

Answer 30

Dengue virus

Question 31

Why is 2nd dengue infection more dangerous?

Answer 31

Serotype is different than 1st infection

Question 32

Specimen of choice for COVID-19 testing?

Answer 32

Nasopharyngeal swab

Question 33

TRUE OR FALSE: For COVID-19 specimen collection, synthetic fiber swabs with thin plastic or wire shafts for sampling the nasopharyngeal mucosa is used

Answer 33

True

Question 34

Method of choice for COVID-19 testing

Answer 34

Nucleic Acid Amplification (RT-PCR)

Question 35

Function of Thermocycler

Answer 35

Amplifies DNA and RNA