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Flashcards in Virology Deck (39)
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1

Viruses differ from living cells in that

They are acellular
Have EITHER DNA or RNA
Unable to reproduce independent of cells

2

For viral replication, a virus must

Invade a host cell and cause it to reproduce viral enzymes and components

3

Viral components are later assembled to form a

Complete virus

4

Bacteriophage are.....to a bacteria

Specific

5

Morphology of a virus

Nuclei acid core (DNA or RNA)
Surrounded by capsid composed of capsomeres

6

Viral symmetries

Icosahedral and helical

7

Lytic

Virulent

8

Lysogenic

Temperate or avirulent

9

Cultivated via

Living host cells

10

virulent bacteriophage may be used in .... for detection. Of and identification of ....

Phage typing

Pathogenic bacteria

11

Bacteria are characterized by their

Resistance or susceptibility to a particular virus

12

The multiplication of a virulent bacteriophage is called the .... because the host is usually lyse in the final stage

Lytic cycle

13

Steps of the lytic cycle

Adsorption/attachment
Penetration
Biosynthesis
Maturation
Lysis

14

Adsorption/attachment

Attachment of particular virus to the cell wall of a specific bacteria. Attachment to specific receptor site

15

Penetration

Injection of nucleic acid of virus into the host. May be chemical (lysozyme) or mechanical

16

Biosynthesis

Nonessential host metabolism is shut down and host genome is degraded.

Host uses viral DNA to produce early proteins (enzymes that degrade the host genome and replicate viral DNA. The host then produces late proteins to synthesize viral components and to assemble those components during maturation.

17

Viral DNA and capsids assembled into complete viruses

Maturation

18

Eclipse

Period of time when no complete viruses are present

19

Lysis

Phage lysozyme lyses bacterial cell wall and the replicated viruses are released. The number of viruses released per host cell is called burst size

20

Picornaviridae

Genus: Enteroviruses - polio viruses
Disease: Polio

Genus: Rhinoviruses
Disease: common cold

21

Calciviridae

Genus: Norovirus
Disease: Acute gastroenteritis

22

Togaviridae

Genus: Rubivirus
Disease: Rubella

23

Orthomyxoviridae

Genus: influenza virus

24

Flavivirdae

Genus: Zika, Dengue, Hep C , Yellow Fever

25

Paramyxoviridae

Mumps virus
Rubeola virus

26

Reoviridae

Rotavirus - vomiting and diarrhea in children

27

Rhabdoviridae

Rabies

28

Retroviridae

HIV1 and HIV2 (aids)
HTLV-1 and HTLV-2 (T cell leukemia)

29

Coronaviridae

Coronavirus - upper respiratory infections, bronchitis

30

Filoviridae

Ebola virus