Flashcards in Viruses and Prions Deck (161)
Triad of mumps symptoms are?
aseptic meningitis, orchitis, and parotitis
If a patient received a hepatitis B vaccine (has no infection), which Ab displays positive serology?
How are alpha and flavi viruses transmitted?
arthropod bites (mosquitos)
Which organisms cause condylomata acuminata?
HPV-6 and HPV-11
What bluish-gray spots on the buccal mucosa re diagnostic of measles?
Which reovirus is considered the most important global cause of infantile gastroenteritis?
What is the major reservoir for Herpes simplex (I and II)?
Which populations is associated with Epstein-Barr virus?
What are the clinical manifestations of coxsackie viruses?
60? of infections are subclinical. Myocarditis or pericarditis (Cocksackie Type B) -usually self limiting but can lead to fatal arrythmia or heart failure.
What is the 'most common' associated with respiratory syncytial virus?
major cause of pneumonia and bronchiolotis in infants
Identify relevant epidemiology and risk factors associated with hepatitis D.
coinfection with HBV
What is the morphology of Varicella zoster?
dNA enveloped herpes virus
What is the morphology of parainfluenza virus?
enveloped RNA virus
Prions: Prions are associated with ________ encephalopathy
What is the morphology of hepatitis D?
incomplete viral particle
All DNA viruses are dsDNA except ______________.
What are the clinical manifestations parvovirus B19? (3)
erythema infectiosum (fifth disease)-4-12 days incubation followed by a mild flu-like illness, a slapped-cheek rash which spreads to legs and arms with a lacy macular pattern 1-2 days later.
Which hep virus has a long incubation period?
B (3 months)
Identify the major virulence/toxicity factors associated wit prions.
do not cause inflammation; not recognized by immune system; resistant to heat, chemicals, UV light or enzymes
Identify the major virulence/toxicity factors associated with adenovirus. (1)
has hemagglutinin fiber to help it attach to mucosal epithelium.
What is the morphology of rhinovirus?
small single stranded RNA virus
What is the #1 cause of fatal diarrhea in children?
rotavirus (a reovirus)
From where do herpesviruses acquire their envelopes?
nuclear membrane of the host cell
Which lab findings are useful to help diagnose respiratory syncytial virus? (2)
chest x-ray shows interstitial infiltrates and areas of collapse; Antigens detected in respiratory secretions
What is the morphology of coxsackle viruses?
What is the 'most common' associated with parainfluenza virus?
How is poliovirus transmitted?
What is the morphology of parvovirus B19?
small DNA virus, single stranded, linear
What are the clinical manifestations of Herpes simplex (I and II)? (2)
type I-lesions above waitst, esp around the face (cold sores). type II-primary painful lesions below the waist with fever and inguinal lymph node enlargement.