Flashcards in Vits II Deck (87)
What are the normal biological processes that generate ROS?
What is the enzyme that converts Hydroxyl radicals to H2O2?
What is the enzyme that catalyses the reaction of hydrogen peroxide to water?
What is the enzyme that converts glutathione and hydrogen peroxide to water?
Is bilirubin an antioxidant?
alpha (or gamma) tocopherol is also known as what?
beta and alpha carotene are lipid or water soluble?
Lycopene is a lipid or water soluble antioxidant
Lutein is a lipid or water soluble antioxidant?
What are the three metals that are involved in superoxide dismutase reaction?
What is the metal involved in glutathione peroxidase?
Urate is a lipid or water soluble antioxidant?
Which can be supplemented in the diet: glutathione or lipoate?
What are the two vitamins in the glutathione/lipoate redox cycles? Which amino acid?
E and C
Why are the brain and lung particularly susceptible to ROS?
High oxygen exposure
True or false: vitamin E alone has been shown to reduce the incidence of CVD
True or false: some studies show that vit E and C supplementation can reduce the amount of plaques in vessels
True or false: the more colorful the vegetable, the more antioxidants it is likely to have
True or false: whole foods have not been shown to have increased antioxidant activity
False-there are studies, but MOA unknown
Higher serum levels of what antioxidants have been shown to lower the risk of developing macular degeneration
Higher serum levels of which 5 vitamins (and one metal) have been shown to lower the risk of developing macular degeneration?
True or false: treatment of AMD with vit C, E, beta carotene, Zn and Cu has been shown to slow the progression of AMD
What are the factors that are needed to ensure sufficient fat soluble vitamin uptake?
Bile salts and carrier proteins
Which fat soluble vitamin does not have a TUL?
Vitamin A is involved in what important reaction in the eye?
Beta-carotene to retinol
Which vitamin metabolites are involved in growth and differentiation of epithelial, nervous, bone, and immune function?
Deficiency in vitamin A results in what?
Poor dark light adaptation
What are the two general sources of vitamin A?
Dark green vegetables
Orange fruits and vegetables
What is the function of vitamin D?
Regulator of bone metabolism and Ca