W1 - Cervical and Vulva Cancer Screening and Pathogenesis Flashcards
(14 cards)
what types of HPV cause cervical caner
types 16,18,31,33,35
what are some risk factors for cervical cancer
multiple partners
STD’s
early age of SI.
smoking
immunosuppression (HIV and transplant patients)
what are the HPV factors which promote oncogenesis
E6 and E7
how does cervical cancer present
Post coital bleeding
Inter-menstrual bleeding
Pelvic pain
Discharge
what are the 2 types of cervical cancer
squamous
adenocarcinoma
what subtype is the most common type of cervical cancer
squamous - 70%
what stage is this
stage 1
what stage is this
stage 2
what stage is this
stage 3
what stage is this
stage 4
how common is vulva cancer
Least common gynaecological malignancy
what is the 5 year survival rate of vulva cancer
58% 5 year survival for all stages
what are some risk factors for vulva cancer
HPV
Lichen Sclerosis 3%
Paget’s disease
evidence of malignancy elsewhere
smoking and immunosuppression
what is the most common type of vulva cancer
90% = Squamous carcinoma
