W1 - Diagnosis and Management of Ovarian Cancer Flashcards
(12 cards)
what are some risk factors of ovarian cancer
Nulliparity
Early menarche
Late menopause
Increasing age
Fertility treatment
White race
Residence in North America or Northern Europe
Family history (one family member: 4-5% risk)
Personal history of breast cancer
Ethnic background
what genes predispose someone to ovarian cancer
BRCA1
BRCA2
HNPCC (Lynch II)
what cancer test can be seen for ovarian cancer
CA125
why is there no sceening for ovarian cancer
significant numbers of false positives from CA125
what is the most common type of ovarian cancer
85% epithelial tumours
what are some of the subtypes of ovarian cancer
Epithelial
Borderline tumours
Germ cell tumours
Sex-cord stromal tumours
Secondary tumours can occur (breast and bowel)
what are the most common symptoms of ovarian cancer
abdo pain
abdo bleeding
abdo distension
abdo mass
urinary urgency
post menopausal bleeding
loss of appetite
what are the FIGO staging for stage 1, 2, 3, 4
Stage I: confined to ovaries
Stage II: confined to pelvis
Stage III: outside pelvis
Stage IV: distant mets (liver, lung)
how is chemotherapy given for ovarian cancer
given every 3 weeks, for 6 cycles
what are some prognostic factors for ovarian cancer
Tumour stage and type
Age
Performance status
Degree of debulking at primary laparotomy
what is the 5 year prognosis of ovarian cancer
what are soe tumour markers for ovarian cancer
hCG:
AFP:
LDH: dysgerminomas
