W10 - Diabetes Flashcards
(15 cards)
Define diabetes
Metabolic disorder
It is the absence, deficit or resistance to insulin leading to hyperglycaemia
What are the 2 types of diabetes
Type 1 & type 2
Explain what type 1 diabetes is
Insulin dependant diabetes mellitus (linked with viral infection & autoimmune disease)
Explain what type 2 diabetes is
Non-insulin dependent diabetes mellitus (linked with obesity, age & ethnicity)
Risk factors of type 1 diabetes
Family history, viral infection
Risk factors of type 2 diabetes
Obesity, hypertension, poor lifestyle & diet
What are the cells of the pancreas called
Islet of langerhans
Name the 3 hormone secreting cells of the islet of langerhans
Alpha cells
Beta cells
Delta cells
What are alpha cells
Maintain blood glucose between meals
Secreate glucogon = utilises glycogen from the liver
What are beta cells
Secreate insulin which promotes the uptake & utilisation of glucose in the blood stream
What are delta cells
Secreate stomatostatin and gastric to regulate the alpha & beta cells
Suppress insulin & glucogon being released
What role does the alpha, beta & delta cells have on the pancreas
Endocrine role
What cells are involved in the exocrine role of the pancreas
Acinar cells
What are the acinar cells
They Secreate digestive enzymes due to being being in close proximity of the stomach they secrete into the duodenum
Where are F cells located
On the periphery