Wbc Flashcards

1
Q

Neutrophilia is what

A

Too many neutrophils

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2
Q

What is nuetrophilia caused by

A

Infection particularly bacterial infection
Inflammation
Infarction
Pregnancy
Exercise rapid shift of neutrophils from marginated pool to circulating pool
Corticosteroids

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3
Q

Neutrophillia toxic change

A

Toxic granulation
Heavy course granulation of neutrophils
Can b feature of pregnancy

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4
Q

Nuetrophillia left shift

A

Left shift means increase in non segmented neutrophils or neutrophils precursors in blood

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5
Q

CML what happens

A

Increase in all granulocytes and their precursors in blood and bone marrow
Translocation of chromosome 9 n 22
Forms Philadelphia chromosome
Bcr abl 1 gene encodes a protein with uncontrolled tyrosine kinase activity
Many divisions

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6
Q

CML features

A

Large spleen

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7
Q

How can cml be stopped

A

Inhibited by specific tyrosine kinase inhibitor

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8
Q

Nuteropenia

A

Too few neutrophils

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9
Q

Neutropenia causes

A

Chemo radiotherapy
Auto immune
Bacterial infections viral
Drugs

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10
Q

Hypersegmented neutrophils

A

Increase in avrg number of neutrophils lobes

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11
Q

Hypersegmented neutrophils cause

A

Lack of b12
Folic scid
Megaloblastic anaemia

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12
Q

Eosinophilia

A

Too many eosinophils

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13
Q

Eonisophil cause

A

Allergy
Parasitic infection
Can occur in Leukemia

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14
Q

Basophils

A

Too many basophils

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15
Q

Monocytosis cause

A

Too many monocytes

Infection or chronic inflammation

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16
Q

Lekiema

A

CML nuetrophilia basophilia eosinophilia
All blast cells and lymphoblast in the blood
Cll lymphocytosis
Bacterial nuetrophilia n monocytosis
Viral. Lymphocytosis
Parasitic eosinophilia
All transient

17
Q

Lymphocytosis cause

A

Viral infection
2 many lymphocytes

Scalloped margin means huggin of the surrounding rbc

18
Q

Cll

A

Lymphoproliferative disorder

Mostly in elderly

19
Q

All impares …

And causes

A

Haemopoiesis
Leukocutosis
Anaemia normocytic norchromic
Low platelet

20
Q

All treatment

A
Supportive 
Red cells 
Platelets 
Antibiotics 
Systemic chemo 
Or intrathecal chemo
21
Q

Lymphopenia causes

A

HIV
Chemo
Radio
Corticosteroids