Week 1 Diabetes Flashcards
(42 cards)
What are the 3 main types of diabetes?
Type 1, type 2 and gestational diabetes
Explain type 1 diabetes:
It is an autoimmune disease characterised by insulin deficiency due to the destruction of beta cells.
Explain type 2 diabetes:
It is a progressive condition of insulin resistance with small less effective insulin being produced
Explain gestational diabetes:
It is a glucose intolerance during pregancy
How is glucose made?
Through the breakdown of carbs through the digestive process
What is the pathogenesis of type 1 Diabetes?
The body attacks its own beta cells. Caused by an environmental trigger, causing the autoimmune response, destruction of beta cells, therefore, no insulin production
What is the pathogenesis of type 2 Diabetes?
The bgl rise in the bloodstream, some in glucose going to the brain and the pancreas is overworked and cannot produce the same amounts of insulin.
How to manage type 1 diabetes?
Insulin therapy
How to manage type 2 diabetes?
Lifestyle changes, medication and insulin
How to monitor glucose?
HbA1C test, finger pricks, or continuous glucose monitoring
What is HbA1C?
It is a blood test that is used to indicate the % of glucose that is in the blood over the last few months
What is a hypoglycemia mmol/L?
below 4 in adults and below 6 in elderly
What is hyperglycemia mmol/L?
Above 15mmol/L
What is the cause of hypoglycaemia?
too much medication, delayed meals, low carbs, alcohol
What are the symptoms of hypoglycaemia?
Sweating, shaking, raised BPM, hungry, headache, unfocused, aggressive
How to treat hypoglycaemia?
15g of fast-acting carb every 15 minutes until bgl over 4mmol/L and a long-acting carb once over.
What is DKA?
diabetic ketone acidosis
What are the signs of DKA?
Blurred vision, rapid breathing, weight loss, polyuria, polydipsia, vomiting, pain and smelly breath
Explain diabetic ketone acidosis?
Diabetic ketoacidosis is when there are high levels of blood acids called ketones.
What is HbA1c also known as?
glycated haemoglobin
Explain patho of HbA1c?
It is when glucose binds with red blood cells. The body does not use this insulin up properly therefore it remains in the blood and a high HbA1c indicts too much sugar in the blood.
How does DKA happen?
The body can’t produce enough insulin. The body breaks down fat as fuel. This process produces a buildup of acids in the bloodstream called ketones, eventually leading to diabetic ketoacidosis if untreated.
What do blood tests look for in diabetic people?
Blood tests, including fasting blood glucose, postprandial blood glucose, HbA 1c , fructosamine, lipid profile, blood urea nitrogen and serum creatinine, electrolytes, islet cell autoantibodies
• Urine for complete urinalysis, microalbuminuria
What is a normal blood glucose level for someone without diabetes?
3.5-7.8 mmol/L