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Flashcards in Week 139 - Influenza Deck (61)
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1

What is a Virion?

This is the complete virus particle as it exists outside of the cell.

2

What is the general structure of a virus?

• Nuclecapsid - This is the genome and the capsid.
-Genome - Genetic information
- Capsid - Protein coat for the genome made of of capsomeres.

• Envelope - Not always present, some viruses are 'naked'.
- Lipid bilayer, formed from host cell.
- Protein and glycoprotein spikes.

3

How may the genetic material in a virus be stored?

The Genome

May be RNA or DNA
May be Single stranded or Double Stranded
May be +ve or -ve

4

What is the significance if a virus stores its genetic information in +ve stranded RNA?

It can be directly translated into a protein, whilst a -ve strand needs to be transcribed first.

5

What family of DNA viruses are single-stranded and enveloped? Give an example of this family and what it causes.

Parvoviridae

- Parvovirus B19 - Causes 'slapped cheek syndrome', (Erythema infectiosum).

6

What family of viruses does the Parvovirus B19 belong to? And what does it cause?

Parvoviridae family, Single-stranded, enveloped DNA virus.

Causes 'slapped cheek' syndrome (Erythema infectorium - A rash in children, dangerous during pregnancy and sickle cell.

7

Which three familys of viruses are Double stranded, DNA and enveloped?

• Hepadnaviridae

• Herpesviridae

• Poxviridae

8

How is the genetic information stored in the hepadnaviridae family of viruses? Give examples.

Double stranded, DNA, Enveloped.

• Hepatitis B

9

Hepatitis B belongs to which family of viruses?

Hepadnaviridae (Double stranded, DNA, Enveloped)

10

What are the qualities of the Herpesviridae family of viruses and give some examples.

Double stranded, DNA, Enveloped.

• Herpes simplex

• Herpes Zoster

• Cytomegalovirus

• Epstein-Barr virus

• Human Herpesvirus 6,7 +8.

11

What family of viruses does herpes simplex belong to? What does it cause?

Herpesviridae (Double stranded,DNA,Enveloped)

Oral and genital ulcers.

12

What family of viruses does herpes zoster belong to? What does it cause?

Herpesviridae (DNA, Double-stranded, Enveloped)

Chickenpox and Shingles.

13

What family of viruses does cytomegalovirus belong to? What does it cause?

Herpesviridae (DNA, Double-stranded, Enveloped)

CMV infections, normally affect salivary glands and is asymptomatic but can be life-threatening during pregnancy and immuno-suppression.

14

What family of viruses does the Epstein-Barr virus belong to? What does it cause?

Herpesviridae (Double-stranded, DNA, Enveloped)

Glandular fever.

15

What are the characteristics of the poxviridae family of viruses? Give examples.

Double-stranded, DNA, Enveloped

• Molluscum Contagiosum

• Variola/Vaccina

16

What family of viruses to Molluscum Contagiosum belong to? What does it cause?

Poxviridae (DNA, Double-stranded, Enveloped)

Molluscum Contagiosum - common in children.

17

What family does the Variola/Vaccina virus belong to? What does it cause?

Poxviridae (DNA, Double-stranded, Enveloped)

Smallpox/ cowpox.

18

Which 2 viruses are DNA, Double-stranded but non-eveloped?

• Adenovirus

• Papillomavirus

19

What are the characteristics of the Adenovirus and what does it cause?

DNA, Double Stranded, Non-enveloped.

• URTIs and Gastroenteritis

20

What are the characteristics of the Papillomavirus and what does it cause?

DNA, Double-stranded, Non-Enveloped

• Warts

21

What are the three virus families that are -ve single stranded RNA and Enveloped?

• Orthomyxoviridae

• Paramyxoviridae

• Rhabdoviridae

22

What are the characteristics of the Orthomyxoviridae family of viruses and give an example.

• RNA, -ve single-stranded, Enveloped.

• Influenza

23

What family of viruses does influenza belong to?

Orthromyxoviridae (RNA, -ve singlestranded, Enveloped)

24

What are the characteristics of the Paramyxoviridae family of viruses and give some examples.

RNA, -ve single-stranded, Enveloped

• Respiratory Synctial Virus

• Parainfluenza Virus

• Measles Virus

 Mumps Virus

25

What family does the Respiratory Syncytial virus belong to? What does it cause?

Paramyxoviridae (RNA, -ve Single-stranded, Enveloped)

• RTIs, esp. Bronchiliotis

26

What family does the Parainfluenza virus belong to? What does it cause?

Paramyxoviridae (RNA, -ve Single-Stranded, Enveloped)

• RTIs esp. Croup

• URTIs causing barking cough

27

What family do the Measles and Mumps viruses belong to?

Paramyxoviridae (RNA, -ve Single-stranded, Enveloped)

28

What virus is a member of the Rhabdovirus family and what are the characteristics of the family?

Rabies

RNA, -ve single-stranded, enveloped.

29

Which three viral families are +ve RNA, single-stranded and non-enveloped?

• Calciviridae

• Picomviridae

• Astroviridae

30

What are the characteristics of the Calciviridae family of viruses? Give examples.

RNA, +ve single-stranded, non-enveloped.

• Norovirus