week 4 module 13 lymph system Flashcards

1
Q

infants

A

lymph system begins development at 20wks gestation
immature at birth
inc. in childhood especially 6-9y/o

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2
Q

preg.

A

temporary remission of autoimmune/inflammatory disorders

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3
Q

older adults

A

nodes dec. size and number with age

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4
Q

HPI enlarged nodes

A

character: onset, location, duration, number
local s/s: pain, redness, warmth, red streaks
systemic s/s: malaise, fever, wt. loss, night seat, abd. pain
predisposing factors: infection, surgery, trauma
meds: chemo, antibiotics

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5
Q

HPI swelling of extremity

A

uni/bilateral
intermittent or constant
predisposing factors: CV or renal disorder, surgery, infection, trauma, venous insufficiency.
assoc. s/s: warmth, redness/discoloration, ulceration

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6
Q

PMH

A

chest imaging
TB
blood transfusions, use of blood products
Chronic illness: cardiac, renal, malignancy, HIV
surgery: trauma, organ transplant, lymph node biopsy
recurrent infections
autoimmune disorders
allergies

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7
Q

FH

A
malignancy
anemia
recent infectious disease
TB
immune disorders
hemophilia
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8
Q

personal and social hx

A

travel: asia, africa, wester pacific, india, philippines
recreational drugs
sexual hx

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9
Q

infants and childrens hx

A

recurrent infections

- tonsillitis, adenoiditis, bacterial infections, oral candidiasis, chronic diarrhea, chronic severe ecamea

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10
Q

preg patients

A

weeks of gestation
exposure to infections
pets in household: cat feces
immunization status

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11
Q

older adults

A

autoimmune disease
recent infection or traume to nodes
delayed healing
immunization status

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12
Q

lymphadenopathy

A

enlarged lymph nodes

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13
Q

lymphadenitis

A

inflamed and enlarged lymph nodes

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14
Q

lymphangitis

A

inflammation of the lymphatics that drain an area of infection; tender erythematous streaks extend proximally from the infected area
- regional nodes may also be tender

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15
Q

lymphedema

A

edematous swelling due to excess accumulation of lymph fluid in tissues caused by inadequate lymph drainage

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16
Q

lymphangioma

A

congenital malformation of dilated lymphatics

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17
Q

shotty nodes

A

small non-tender nodes that feel like BB’s or buckshot under the skin

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18
Q

fluctuant nodes

A

wavelike motion that is felt when the node is palpated

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19
Q

matted nodes

A

group of nodes that feel connected and seem to move as a unit

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20
Q

hard, fixed, painless node

A

suggests malignant process

- usually rapid enlargement

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21
Q

tender node

A

more likely an inflammatory process

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22
Q

virchow node

A

palpable supraclavicular node on left

- clue to thoracic or abdominal malignancy

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23
Q

slow nodal enlargement suggests

A

benign process

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24
Q

acute lymphangitis patho

A

inflammation of one or more lymphatic vessels

25
acute lymphangitis subjective
``` enlarged lymphnode pain malaise possible fever minor trauma to skin distal to the area of infection ```
26
acute lymphangitis objective
red streaks after the course of the lymphatic collecting duct tracing of fine lines streaking up the extremity indurated and palpable to gentle touch sometimes look distal for sites of infection, esp. between digits
27
acute suppurative lymphadenitis patho
infection and inflammation of a lymph node, single or group
28
acute suppurative lymphadenitis subjective
enlarged nodes | pain
29
acute suppurative lymphadenitis objective
involved node usually firm and tender overlying tissue edematous, erythematous, within 72hr abscess formation extensive; nodes fluctuant
30
mycobacterial adenitis characterized by
inflammation without warmth that may or may not be tender
31
lymphedema patho
edematous swelling due to excess accumulation of lymph fluid in tissues caused by inadequate lymph drainage
32
lymphedema subjective
``` painless swelling of limb; uni/bilateral onset usually gradual hx of trauma, surgery, or radiation to area travel where filariasis is common family hx leg swelling ```
33
lymphedema objective
swelling and often distortion of extremities may or may not pit overlying skin thickens and feels tougher than usual
34
primary lymphedema
apparent at birth and most often involves the legs degree varies with the severity and distribution of the abnormality may not appear till young adulthood
35
Stage 0 lymphedema
latent or subclinical | swelling is not evident despite impaired lymph transport
36
Stage 1 lymphedema
pitting may occur early accumulation of fluid relatively high in protein content - subsides with elevation
37
Stage 2 lymphedema
tissue fibrosis is present limb elevation alone rarely reduces swelling pitting may be present, as fibrosis worsens pitting decreases
38
Stage 3 lymphedema
pitting is absent | trophic skin changes are present
39
lymphangioma/cystic hygroma patho
congenital malformation of dilated lymphatics
40
lymphangioma subjective
painless cystic masses usually manifest during 1st year of life - often enlarged after an URI asymptomatic when in posterior triangle of neck - found anteriorly may cause airway/swallowing issues
41
lymphangioma/ cystic hygroma objective
soft, nontender, and easily compressible spongy fluid-containing mass without discrete margins. most present at birth - neck, axilla, less common: chest, extremities
42
lymphatic filariasis (elephantiasis) patho
massive accumulation of lymphedema throughout the body | - widespread inflammation and obstruction of the lymphatics by the filarial worms transmitted by mosquitos
43
lymphatic filariasis (elephantiasis) subjective
swelling of limb or body area travel: asia, africa, western pacific, india, philippines many w/out s/s fever, chronic pulmonary infection
44
non-hodgkin lymphoma patho
malignant neoplasm of the lymphatic system and the reticuloendothelial tissues
45
non-hodgkin's subjective
``` painless enlarged lymph nodes fever wt. loss night sweats abd. pain/fullness family hx ```
46
non-hodgkin's objective
- nodes may be localized in the posterior cervical triangle or may become matted, crossing into the anterior triangle - nodes well defined and solid
47
Hodgkin's lymphoma patho
malignant lymphoma starts in single node and spreads to contiguous lymph nodes, spleen, liver, and bone marrow. neoplastic giant cells release factors that induce accumulation of lymphocytes, macrophages, and granulocytes
48
hodgkin lymphoma subjective
painless enlarged lymph nodes may have abd. pain sometimes fever possible hx of mononucleosis
49
hodgkin lymphoma objective
most common: - painless enlargement of cervical lymph nodes - - generally asymmetric and progressive Nodes sometimes matted and firm, almost rubbery
50
Epstein-Barr virus Mononucleosis patho
infectious mono oral epithelial cells incubation period 30-50 days
51
epstein-barr virus mononucleosis subjective
``` malaise fatigue acute or prolonged fever HA ST nausea abd pain myalgia ```
52
epstein-barr virus mononucleosis objective
- generalized lymphadenopathy, most common in cervical nodes and submandibular - epitrochlear lymphadenopathy - hepatomegaly - splenomegaly - moderate to severe pharyngitis with tonsillar enlargement, occasional exudates - petechiae at the junction of the hard and soft palate
53
toxoplasmosis patho
zoonosis, caused by the parasite toxoplasma gondii - ingestion of oocysts in soil undercooked meat, raw eggs, cat feces or litter - infection persists for life without s/s - immunosuppresion: neurologic disease and organ manifestations - preg: serous congenital infection, particularly in 1st trimester
54
toxoplasmosis subjective
no s/s hx of eating raw or rare meat, undercooked eggs hx contact with cat feces
55
toxoplasmosis objective
single node, chronically enlarged and nontender | - usually in the posterior cervical chain
56
roseola infantum patho
infection by human herpes virus 6 - common in infancy peak age 2 years - present in the saliva of most adults transmitted by oral secretions
57
roseola infantum subjective
fever- high grade and persistant over 3-4 days | may have mild resp. illness and lymphadenopathy
58
roseola infantum objective
- adeopathy, discrete and not tender, involves the occipital and postauricular chains, may last for some time. - when fever diminishes, morbillifrom fine maculopapular rash occurs, spreads from trunk to extremities, then child begins to feel better