Week 8: Disorders of Ca2+ Homeostasis Flashcards by Jay Sandoval

Q

Principles of Ca2+ physiology

A

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Q

What is extracellular Ca2+ needed for?

A

is required to maintain normal biological function of nervous system and blood coagulation

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Q

What is intracellular Ca2+ needed for?

A

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Q

How does Ca2+ circulate

A

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Q

Describe the mechanisms of normal Ca2+ flux

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Q

Describe hormone and Ca2+ homeostasis

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Q

Describe Calcitonin

A

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Q

Describe PTH

A

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Q

Parathyroid glands

A

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Q

Normal parathyroid function requires how many glands

A

at least 2 of the 4 functioning glands

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Q

Renal parathyroid hormone effects

A

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Q

Bone parathyroid hormone effects

A

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Q

Gut parathyroid hormone effects

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Q

Interpreting PTH & Ca2+ lab tests

A

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Q

Describe Vitamin D

A

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Q

Describe Vitamin D metabolism

A

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Q

Describe Vitamin D metabolism

A

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Q

Hypocalcemia

A

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Q

DDx of hypocalcemia

A

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Q

Primary hypoparathyroidism

A

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Q

Pseudohypoparathyroidism

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A

Q

Vitamin D deficiency

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A

Q

Vitamin D dependent Rickets Type 1

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A

Q

Vitamin D dependent Rickets Type 2

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A

Acute Tx of hypocalcemia

Tx of chronic hypocalcemia

DDx of hypercalcemia

Complications of hypercalcemia

Primary hyperparathyroidism

Clinical features of HPT

Primary Hyper PTH clinical features

Hyper PTH Work-up

Lab abnormalities in HPT

Indications for surgery in primary HPT

Other considerations for surgery for HPT

Pre-operative imaging

Parathyroid adenomas imaging

Technitium99-Sestamibi

Natural Hx of Asymptomatic HPT

Medical management primary HPT

Familial Syndromes of HPT

MEN syndromes

Granulomatous Disease

Hypercalcemia of malignancy

Medications for hypercalcemia of malignancy

Familial benign hypercalcemia

Creatinine Clearance ratio

Secondary PTH: Renal failure

Secondary hyper-PTH

Tertiary HPT

Other causes of hypercalcemia

Sally brooks

Disorders of Ca2+ homeostasis Conclusions