Wk4 Small intestine/Colon Pathology Flashcards Preview

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Flashcards in Wk4 Small intestine/Colon Pathology Deck (33)
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1
Q

Most common cause of acute diarrhea:

A

infectious

2
Q

Two types of inflammatory bowel disease:

A

ulcerative colitis

Crohn’s

3
Q

Inflammatory changes involving mucosa and submucosa

limited to colon and rectum

A

Ulcerative colitis

4
Q

Transmural inflammatory changes

any area of GI tract

“skip lesions”

A

Crohn’s

5
Q

Pseudopolyps

A

UC

6
Q

Ulcerations

Fissures

A

Crohn’s

7
Q

Branched crypts

A

UC

8
Q

non-caseating granulomas

A

Crohn’s

9
Q

Cobblestone

A

Crohn’s

10
Q

Creeping fat

Fistulas

A

Crohn’s

11
Q

bloody diarrhea with mucus

A

UC

12
Q

presentation of Crohn’s

A

variable

13
Q

ASCA positive

A

Crohn’s

14
Q

pANCA positive

A

UC

15
Q

Toxic megacollon

A

UC

16
Q

Small bowel strictures

perforation

fistulas

A

Crohn’s

17
Q

Long term complication of UC and CD

A

intestinal adenocarcinoma

18
Q

colitis after surgery

A

diversion colitis

19
Q

cause of diversion colitis

A

loss of short chain fatty acids

20
Q

chronic watery diarrhea with normal colonoscopy

A

microscopic colitis

21
Q

Two types of microscopic colitis:

A
  1. lymphocytic

2. collagenous

22
Q

Mechanism of microscopic colitis:

A

autoimmune

23
Q

Mucosal patchy erythema

telangiectasias

A

Radiation enterocolitis

24
Q

pneumonitis intestinalis

air bubbles

A

neonatal necrotizing enterocolitis

25
Q

apoptotic cell death in crypts without inflammation

A

graft vs host disease

26
Q

unexplained constipation or diarrhea

A

Irritable Bowel Syndrome

27
Q

Common locations of Ischemic bowel disease:

A

watershed zones

splenic flexure

sigmoid colon

28
Q

atrophy of surface epithelium

coagulative necrosis

possible sepsis

A

Ischemic bowel disease

29
Q

Risk factor for ischemic bowel disease

A

cardiac or vascular disease

30
Q

malformed mucosal and submucosal blood vessels

A

Angiodysplasia

31
Q

caused by elevated intraluminal pressure in the sigmoid colon

A

Sigmoid diverticulitis

32
Q

malfunction in puborectalis muscle

A

solitary rectal ulcer syndrome

33
Q

fibromuscular dysplasia of lamina propria

A

solitary rectal ulcer syndrome