Wk4 Small intestine/Colon Pathology

Question 1

Most common cause of acute diarrhea:

Answer 1

infectious

Question 2

Two types of inflammatory bowel disease:

Answer 2

ulcerative colitis

Crohn’s

Question 3

Inflammatory changes involving mucosa and submucosa

limited to colon and rectum

Answer 3

Ulcerative colitis

Question 4

Transmural inflammatory changes

any area of GI tract

“skip lesions”

Answer 4

Crohn’s

Question 5

Pseudopolyps

Answer 5

UC

Question 6

Ulcerations

Fissures

Answer 6

Crohn’s

Question 7

Branched crypts

Answer 7

UC

Question 8

non-caseating granulomas

Answer 8

Crohn’s

Question 9

Cobblestone

Answer 9

Crohn’s

Question 10

Creeping fat

Fistulas

Answer 10

Crohn’s

Question 11

bloody diarrhea with mucus

Answer 11

UC

Question 12

presentation of Crohn’s

Answer 12

variable

Question 13

ASCA positive

Answer 13

Crohn’s

Question 14

pANCA positive

Answer 14

UC

Question 15

Toxic megacollon

Answer 15

UC

Question 16

Small bowel strictures

perforation

fistulas

Answer 16

Crohn’s

Question 17

Long term complication of UC and CD

Answer 17

intestinal adenocarcinoma

Question 18

colitis after surgery

Answer 18

diversion colitis

Question 19

cause of diversion colitis

Answer 19

loss of short chain fatty acids

Question 20

chronic watery diarrhea with normal colonoscopy

Answer 20

microscopic colitis

Question 21

Two types of microscopic colitis:

Answer 21

1. lymphocytic

2. collagenous

Question 22

Mechanism of microscopic colitis:

Answer 22

autoimmune

Question 23

Mucosal patchy erythema

telangiectasias

Answer 23

Radiation enterocolitis

Question 24

pneumonitis intestinalis

air bubbles

Answer 24

neonatal necrotizing enterocolitis

Question 25

apoptotic cell death in crypts without inflammation

Answer 25

graft vs host disease

Question 26

unexplained constipation or diarrhea

Answer 26

Irritable Bowel Syndrome

Question 27

Common locations of Ischemic bowel disease:

Answer 27

watershed zones splenic flexure sigmoid colon

Question 28

atrophy of surface epithelium coagulative necrosis possible sepsis

Answer 28

Ischemic bowel disease

Question 29

Risk factor for ischemic bowel disease

Answer 29

cardiac or vascular disease

Question 30

malformed mucosal and submucosal blood vessels

Answer 30

Angiodysplasia

Question 31

caused by elevated intraluminal pressure in the sigmoid colon

Answer 31

Sigmoid diverticulitis

Question 32

malfunction in puborectalis muscle

Answer 32

solitary rectal ulcer syndrome

Question 33

fibromuscular dysplasia of lamina propria

Answer 33

solitary rectal ulcer syndrome