XII - Mycology Flashcards
(88 cards)
Fungi are ___karyotic
eukaryotic
Fungi have complex carbohydrate walls composed of
chitin, glucan, mannan
Major membrane sterol in fungi
ergosterol
Antifungals: Inhibit ergosterol synthesis
Imidazole
Antifungals: Bind more tightly to ergosterol than cholesterol
Polyene
Fungi require _____ (heterotrophic nutrition).
organic carbon
Living in dead organic matter
saphrophytic or saprobic
Living on another living organism
parasitic
Basic Forms of Fungi: Single cells, budding
yeast
Basic Forms of Fungi: Hyphae, mycella (bouquet of hyphae), mitosis
molds
Fungi exhibit thermal _____.
thermal dimorphism
Hyphae: Septate
transverse walls
Hyphae: Non-septate
multinucleated
Basic Forms of Fungi: Room Temp.
mold
Basic Forms of Fungi: Body Temp.
yeast
Host response to fungal infection
granulomatous, pyogenic
Fungi: Liver necrosis due to amantin and phylloidin
Amanita mushrooms
Fungi: Ingestion of contaminated peanuts and grains causes liver cancer due to aflatoxin
Aspergillus flavus
Fungi: Inhalation of the spores cause allergic bronchopulmonary aspergillosis (ABPA, IgE-mediated)
Aspergillus fumigatus
Fungi Diagnosis: Dissolves human cells allowing visualization
KOH microscopy
Fungi Diagnosis: Low pH inhibits the growth of bacteria
Sabouraud agar
Fungi Diagnosis: Used for early infection
DNA probes
Fungi: Infect only superficial keratinized structures
Dermatophytoses
3 Important Dermatophytes
Microsporum canis, Trichophyton tonsurans, Epidermophyton floccosum