XI - Other Bacteria Flashcards Preview

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Flashcards in XI - Other Bacteria Deck (173)
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1

Zoonoses

Brucella abortus, Francisella tularensis, Yersinia pestis, Pasteurella multocida

2

Small gram (-) rods without a capsule, contaminated dairy, direct contact, undulating fever

Brucellosis

3

Brucellosis: Cow

B. abortus

4

Brucellosis: Dog

B. canis

5

Brucellosis: Goat/Sheep

B. melitensis

6

Brucellosis: Sheep

B. ovis

7

Brucellosis: Treatment

Doxycycline + Rifampin

8

Small gram (-) rods, reservoir - rabbits, deer, rodents, transmission - ticks (Dermacentor), aerosols, contact, ingestion

Francisella tularensis (Tularemia)

9

Francisella tularensis: Treatment

Streptomycin, Gentamicin

10

Most virulent bacteria

Yersinia pestis

11

Small gram (-) rods with bipolar (safety pin) staining, reservoir - rodents, transmission - flea bite, inhalation

Yersinia pestis

12

Buboes, cutaneous hemorrhage

Yersinia pestis

13

Bubonic, Pneumonic and Septicemic Plague

Yersinia pestis

14

Yersinia pestis: Treatment

Streptomycin, Tetracycline

15

Short encapsulated gram (-) rod that exhibits bipolar staining, buttery colonies with musty odor due to indole production, osteomyelitis, reservoir - cats and dogs, transmission - animal bites

Pasteurella multocida

16

Pasteurella multocida: Treatment

Penicillin G

17

Aerobic, acid-fast rods, Ziehl-Neelsen (hot), Kinyoun (cold), high lipid content, mycolic acids, wax D, produces catalase and niacin, slow-growing on Löwenstein–Jensen medium (1 mo.), luciferase assay for drug resistance

Mycobacterium tuberculosis

18

Mycobacterium tuberculosis: Location

lungs

19

Mycobacterium tuberculosis: Transmission

respiratory droplets from coughing

20

TB Virulence Factors: Prevents phagosome-lysosomal fusion

Exported Repetitive Protein (Sulfatides)

21

TB Virulence Factors: Most important VF, prevents leukocyte migration

Cord Factor

22

TB Virulence Factors: Elicits delayed hypersensitivity

Tuberculin Surface Protein (Purified Protein Derivative - PPD)

23

Mycobacterium tuberculosis: Lesions

exudative, granulomatous

24

Central area of Langhan's giant cells surrounded by a zone of epithelioid cells, tubercle is a granuloma surrounded by fibrous tissue that has undergone central caseation

Mycobacterium tuberculosis Granulomatous Lesions

25

TB Phase of Infection: Middle-lower lobes, subpleural granuloma, CLAD, radiologically detectable calcification

Primary Complex

26

TB: Subpleural Granuloma

Ghon's Focus

27

TB: Subpleural Granuloma + Associated LN

Ghon's Complex

28

TB: Radiologically Detectable Calcification

Ranke's Complex

29

TB Phase of Infection: Apices (Simon's Focus), cicatricial changes, subpleural blebs, cavitation, fibrosis, nodules, secondary colonization with A. fumigatus (fungus ball), pneumothorax

Reactivation TB

30

Reactivation TB: X-ray Findings

apices (Simon's Focus), cicatricial changes, subpleural blebs, cavitation, fibrosis, nodules