Flashcards in XVIII - The Male Genital System Deck (61)
A chronic venereal infection caused by the spirochete Treponema pallidum, whose fundamental microscopic lesion is a proliferative endarteritis and an accompanying inflammatory infiltrate rich in plasma cells.
Syphilis(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 702
An irregular, firm mass of necrotic tissue surrounded by resilient connective tissue. Contains a central zone of coagulation necrosis surrounded by a mixed inflammatory infiltrate composed of lymphocytes, plasma cells, epithelioid cells, giant cells, and a peripheral zone of dense fibrous tissue. Seen in tertiary syphilis.
Gumma(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 702
This stage of syphilis is characterized by the presence of an indurated chancre at the site of initial inoculation, associated with painless regional lymphadenopathy.
Primary Syphilis (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 702
Both nontreponemal and antitreponemal antibody tests are strongly positive in virtually all cases of this stage of syphilis.
Secondary syphilis(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 702
In males this is manifested most often as a purulent urethral discharge, associated with an edematous, congested urethral meatus. Gram stain of urethral discharge, demonstrates the characteristic gram-negative, intracellular diplococci.
Gonorrhea (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 705
A gram-negative intracellular bacterium that causes a disease that is clinically indistinguishable from gonorrhea in both men and in women.
Chlamydia trachomatis(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 707
C. trachomatis infection causing a triad of reactive arthritis, conjunctivitis and generalized mucocutaneous lesions.
Reiter syndrome(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 707
This STD is a chronic, ulcerative disease caused by certain strains of C. trachomatis, which presents with nonspecific urethritis, papular or ulcerative lesions involving the lower genitalia, regional adenopathy, or an anorectal syndrome.
Lymphogranuloma venereum (LGV) (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 707
This STD is an acute, ulcerative infection caused by Haemophilus ducreyi, a small, gram-negative coccobacillus. The lesion is an irregular ulcer, whose base is covered by a shaggy, yellow-gray exudate. Regional lymph nodes are enlarged and tender.
Chancroid (Soft Chancre) (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 707
A chronic inflammatory disease caused by Calymmatobacterium granulomatis. The organisms are demonstrable in Giemsa-stained smears of the exudate as minute coccobacilli within vacuoles in macrophages (Donovan bodies). Regional lymph nodes are typically spared.
Granuloma Inguinale (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 708
The initial lesions of this infection are painful, erythematous vesicles on the mucosa or skin of the lower genitalia and adjacent extra-genital sites. Cowdry type A inclusions appear as light purple, homogeneous intranuclear structures surrounded by a clear halo.
HSV 2(TOPNOTCH)Robbins Basic Pathology, 8th ed., p 708
Caused by HPV types 6 and 11. Lesions vary from small, sessile lesions to large, papillary proliferations measuring several centimeters in diameter.
Condylomata acuminata (TOPNOTCH)Robbins Basic Pathology, 8th ed., p 709
What is the most common cause of hydronephrosis in infants and children?
Ureteropelvic junction obstruction (TOPNOTCH)
Fiery red appearance of the cervix is associated with what type of infection?
Strawberry cervix is associated with T. vaginalis infection (TOPNOTCH)
Approximately 70% of prostate carcinoma will arise in what zone of the gland?
Peripheral zone ( posterior location) (TOPNOTCH)
What is the best known grading system for Prostate Carcinoma?
Gleason System (TOPNOTCH)
Morphology: hallmark is nodularity due to glandular proliferation or dilation and to fibrous or muscular proliferation of the stroma
Nodular hyperplasia of the prostate originates almost exclusively in what zone of the gland?
Transition zone (TOPNOTCH)
Morphology: appear as minute, disseminated abscesses or diffuse edema, congestion, and boggy suppuration of the entire prostate
Acute prostatitis (TOPNOTCH)
Morphology: aggregation of numerous lymphocytes, plasma cells, and macrophages as well as neutrophils within the prostatic substance
Chronic prostatitis (TOPNOTCH)
Morphology: tumor cells are arranged in distinctive trabeculae with a tendency to form cordlike structures resembling immature seminiferous tubules
Sertoli Cell Tumors or Androblastoma (TOPNOTCH)
Morphology: rod shaped crystalloids of Reinke
Leydig/Interstitial Cell Tumors (TOPNOTCH)
What is the most common form of testicular neoplasm in men over the age of 60?
Testicular Lymphoma (TOPNOTCH)
Morphology: disorganized collection of lands, cartilage, smooth muscle, and immature stroma
Teratoma of the testes (TOPNOTCH)
What do you call the structures resembling endodermal sinuses that may be seen in Yolk Sac Tumor?
Schiller Duval Bodies (TOPNOTCH)
Morphology: reveals large cells with distinct cell borders, pale nuclei, clear or watery appearing cytoplasm, prominent nucleoli, and a sparse lymphocytic infiltrate
Within how many hours should the testes be explored surgically and untwisted manually so the testes will be viable after a testicular torsion?
(TOPNOTCH) Within 6 hours
Morphology: clear vacuolization of the prickle cells
Condylomata acuminatum (koilocytosis) (TOPNOTCH)
What HPV DNA type is found in approximately 80% of Bowen Disease and bowenoid papulosis?
HPV Type 16 (TOPNOTCH)