Flashcards in XXIII - The Nervous System (with pics) Deck (213)
Alzheimer-related lesions. PLAQUE or TANGLE: Bundles of paired helical filaments visible as basophilic fibrillary structures. A major component is an abnormally hyperphosphorylated TAU protein. Not specific for Alzheimer's.
Tangle. SEE SLIDE 23.11. (TOPNOTCH)Robbins Basic Pathology, 9th ed., p 838
In Parkinson's Disease, where are Lewy bodies appear first?
Interesingly, it appears first in the medulla, and then the pons, before involvement of the substantia nigra. (M>P>S in alphabetical order) (TOPNOTCH)Robbins Basic Pathology, 9th ed., p 839