0-1 Chapter 14 Brain and Cranial Nerves Flashcards

(185 cards)

1
Q

rostral

A

toward the forehead

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2
Q

caudal

A

toward the spinal cord

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3
Q

three major portions of the brain

A

cerebrum, cerebellum, brainstem

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4
Q

cerebrum

A

cerebrum is 83% of brain volume; cerebral hemispheres, gyri and sulci, longitudinal fissure, corpus callosum

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5
Q

cerebellum

A

cerebellum contains 50% of the neurons; second largest brain region, located in posterior cranial fossa

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6
Q

brainstem

A

brainstem the portion of the brain that remains if the cerebrum and cerebellum are removed; diencephalon, midbrain, pons, and medulla oblongata

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7
Q

Cerebrum

longitudinal fissure

A

deep groove that separates cerebral hemispheres

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8
Q

Cerebrum

gyri

A

thick folds

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9
Q

Cerebrum

sulci

A

shallow grooves

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10
Q

Cerebrum

corpus callosum

A

thick nerve bundle at bottom of longitudinal fissure that connects hemispheres

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11
Q

Cerebellum

A

about 10% of brain volume
•contains over 50% of brain neurons
•marked by gyri, sulci, and fissures

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12
Q

Cerebellum

occupies

A

occupies posterior cranial fossa

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13
Q

brainstem

A

what remains of the brain if the cerebrum and cerebellum are removed

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14
Q

major components

A

–midbrain
–pons
–medulla oblongata

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15
Q

gray matter

A

the seat of neuron cell bodies, dendrites, and synapses
–dull white color when fresh, due to little myelin
–forms surface layer, cortex, over cerebrum and cerebellum
–forms nuclei deep within brain

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16
Q

white matter

A

bundles of axons
–lies deep to cortical gray matter, opposite relationship in the spinal cord
–pearly white color from myelin around nerve fibers
–composed of tracts, bundles of axons, that connect one part of the brain to another, and to the spinal cord

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17
Q

meninges

A

three connective tissue membranes that envelop the brain
–lies between the nervous tissue and bone
–as in spinal cord, they are the dura mater, arachnoid mater, and the pia mater
–protect the brain and provide structural framework for its arteries and veins

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18
Q

dura mater

in cranial cavity -2 layers

A
  • outer periosteal

* inner meningeal

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19
Q

outer periosteal

A

equivalent to periosteum of cranial bones

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20
Q

inner meningeal

A

continues into vertebral canal and forms dural sac around spinal cord

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21
Q

cranial dura mater is pressed closely against

A

cranial bones
•no epidural space
•not attached to bone except: around foramen magnum, sella turcica, the cristagalli, and sutures of the skull
•layers separated by dural sinuses –collect blood circulating through brain

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22
Q

dura mater

folds inward to extend between parts of the brain

A
  • falx cerebri
  • tentorium cerebelli
  • falx cerebelli
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23
Q

falx cerebri

A

separates the two cerebral hemispheres

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24
Q

tentorium cerebelli

A

separates cerebrum from cerebellum

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25
falx cerebelli
separates the right and left halves of cerebellum
26
arachnoid mater
–transparent membrane over brain surface –subarachnoid space separates it from pia mater below –subdural space separates it from dura mater above in some places
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pia mater
–very thin membrane that follows contours of brain, even dipping into sulci –not usually visible without a microscope
28
meningitis
inflammation of the meninges –serious disease of infancy & childhood –especially between 3 months and 2 years of age •caused by bacterial and virus invasion of the CNS by way of the nose and throat •pia mater and arachnoid are most often affected
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bacterial meningitis
can cause swelling the brain, enlarging the ventricles, and hemorrhage
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ventricles
four internal chambers within the brain
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choroid plexus
spongy mass of blood capillaries on the floor of each ventricle
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ependyma
neuroglia that lines the ventricles and covers choroid plexus –produces cerebrospinal fluid
33
cerebrospinal fluid (CSF)
clear, colorless liquid that fills the ventricles and canals of CNS –bathes its external surface
34
CSF continually flows through and around the CNS
–driven by its own pressure, beating of ependymal cilia, and pulsations of the brain produced by each heartbeat
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CSF is reabsorbed by
arachnoid villi
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arachnoid villi
–cauliflower-shaped extension of the arachnoid meninx –protrudes through dura mater –into superior sagittal sinus –CSF penetrates the walls of the villi and mixes with the blood in the sinus
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Functions of CSF
buoyancy | protection
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buoyancy
–allows brain to attain considerable size without being impaired by its own weight –if it rested heavily on floor of cranium, the pressure would kill the nervous tissue
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protection
–protects the brain from striking the cranium when the head is jolted –shaken child syndrome and concussions do occur from severe jolting
40
chemical stability
–flow of CSF rinses away metabolic wastes from nervous tissue and homeostatically regulates its chemical environment
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Blood Supply to the Brain
brain is only 2% of the adult body weight, and receives 15% of the blood –750 mL/min
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brain barrier system
strictly regulates what substances can get from the bloodstream into the tissue fluid of the brain •two points of entry must be guarded: –blood capillaries throughout the brain tissue –capillaries of the choroid plexus
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blood-brain barrier
protects blood capillaries throughout brain tissue –consists of tight junctions between endothelial cells that form the capillary walls –astrocytes reach out and contact capillaries with their perivascular feet
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endothelial cells can
exclude harmful substances from passing to the brain tissue while allowing necessary ones to pass
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blood-CSF barrier
protects the brain at the choroid plexus –form tight junctions between the ependymal cells –tight junctions are absent from ependymal cells elsewhere •important to allow exchange between brain tissue and CSF
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blood barrier system is highly permeable to
water, glucose, and lipid-soluble substances such as oxygen, carbon dioxide, alcohol, caffeine, nicotine, and anesthetics
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slightly permeable
to sodium, potassium, chloride, and the waste products urea and creatinine
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circumventricular organs
(CVOs) –places in the third and fourth ventricles where the barrier is absent •blood has direct access to the brain
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Hindbrain
Medulla Oblongata
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Medulla Oblongata
* begins at foramen magnum of the skull * extends for about 3 cm rostrally and ends at a groove between the medulla and pons * slightly wider than spinal cord
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Medulla Oblongata nerves & Cranial nerves
* all nerve fibers connecting the brain to the spinal cord pass through the medulla * four pairs of cranial nerves begin or end in medulla -IX, X, XI, XII
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pyramids
pair of external ridges on anterior surface contain descending fibers called corticospinal tracts –carry motor signals to skeletal muscles
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Medulla Oblongata centers
* cardiac center * vasomotor center * respiratory centers * reflex centers
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cardiac center
–adjusts rate and force of heart
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vasomotor center
–adjusts blood vessel diameter
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respiratory centers
–control rate and depth of breathing
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reflex centers
for coughing, sneezing, gagging, swallowing, vomiting, salivation, sweating, movements of tongue and head
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inferior olivary nucleus
relay center for signals to cerebellum
58
reticular formation
loose network of nuclei extending throughout the medulla, pons and midbrain –contains cardiac, vasomotor & respiratory centers
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metencephalon
develops into the pons and cerebellum
60
pons
anterior bulge in brainstem, rostral to medulla
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cerebral peduncles
connect cerebellum to pons and midbrain
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Pons
* ascending sensory tracts * descending motor tracts * pathways in and out of cerebellum
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Pons | cranial nerves
V, VI, VII, and VIII
64
sensory roles
hearing, equilibrium, taste, facial sensations
65
motor roles
eye movement, facial expressions, chewing, swallowing, urination, and secretion of saliva and tears
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reticular formation
reticular formation in pons contains additional nuclei concerned with: –sleep, respiration, and posture
67
midbrain
–short segment of brainstem that connects the hindbrain to the forebrain –contains cerebral aqueduct –contains continuations of the medial lemniscus and reticular formation
68
midbrain cranial nerves
contains the motor nuclei of two cranial nerves that control eye movements –CN III (oculomotor) and CN IV (trochlear)
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tectum
roof-like part of the midbrain posterior to cerebral aqueduct
70
cerebral peduncles
two stalks that anchor the cerebrum to the brainstem anterior to the cerebral aqueduct
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cerebral peduncles | –each consists of three main components
tegmentum, substantia nigra, and cerebral crus
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tegmentum
* dominated by the red nucleus | * connections go to and from cerebellum
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substantia nigra
* dark gray to black nucleus pigmented with melanin | * motor center that relays inhibitory signals to thalamus & basal nuclei preventing unwanted body movement
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cerebral crus
* bundle of nerve fibers that connect the cerebrum to the pons * carries corticospinal tracts
75
reticular formation
loosely organized web of gray matter that runs vertically through all levels of the brainstem •clusters of gray matter scattered throughout pons, midbrain and medulla •occupies space between white fiber tracts and brainstem nuclei •has connections with many areas of cerebrum
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Functions of Reticular Formation Networks
``` somatic motor control cardiovascular control pain modulation***************** sleep and consciousness habituation ```
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gaze center
allow eyes to track and fixate on objects
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Cerebellum
the largest part of the hindbrain and the second largest part of the brain as a whole •consists of right and left cerebellar hemispheres connected by vermis •contains more than half of all brain neurons, about 100 billion
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cerebellar peduncles
three pairs of stalks that connect the cerebellum to the brainstem
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Cerebellar Functions
* monitors muscle contractions and aids in motor coordination * evaluation of sensory input * timekeeping center * hearing * planning and scheduling tasks
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forebrain consists of
–the diencephalon | –the telencephalon
82
Diencephalon: Thalamus
the “gateway to the cerebral cortex” –nearly all input to the cerebrum passes by way of synapses in the thalamic nuclei, filters information on its way to cerebral cortex –plays key role in motor control by relaying signals from cerebellum to cerebrum and providing feedback loops between the cerebral cortex and the basal nuclei –involved in the memory and emotional functions of the limbic system
83
hypothalamus
major control center of autonomic nervous system and endocrine system –plays essential roll in homeostatic regulation of all body systems
84
functions of hypothalamic nuclei
``` –hormone secretion –autonomic effects –thermoregulation –food and water intake –produce sensations of hunger and satiety –rhythm of sleep and waking –memory –emotional behavior ```
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epithalamus
very small mass of tissue composed of: –pineal gland –endocrine gland –habenula–relay from the limbic system to the midbrain
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Telencephalon
Cerebrum
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cerebrum
largest and most conspicuous part of the human brain | –seat of sensory perception, memory, thought, judgment, and voluntary motor actions
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frontal lobe
–voluntary motor functions | –motivation, foresight, planning, memory, mood, emotion, social judgment, and aggression
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parietal lobe
–receives and integrates general sensory information, taste and some visual processing
90
occipital lobe
–primary visual center of brain
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temporal lobe
–areas for hearing, smell, learning, memory, and some aspects of vision and emotion
92
insula
–understanding spoken language, taste and sensory information from visceral receptors
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Cerebral White Matter
most of the volume of cerebrum is white matter –glia and myelinated nerve fibers transmitting signals from one region of the cerebrum to another and between cerebrum and lower brain centers
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three types of tracts
projection tracts, commissural tracts, association tracts
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long association fibers
connect different lobes of a hemisphere to each other
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short association fibers
connect different gyri within a single lobe
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Cerebral Cortex
layer covering the surface of the hemispheres –only 2 –3 mm thick –cortex constitutes about 40% of the mass of the brain –contains 14 –16 billion neurons
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cerebral gray matter found in three places
–cerebral cortex –basal nuclei –limbic system
99
neural integration
is carried out in the gray matter of the cerebrum
100
Cerebral Cortex contains two principal types of neurons
stellate cells | pyramidal cells. -only neurons that leave the cortex and connect with other parts of the CNS
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basal nuclei
Involved in motor control
102
limbic system
Creates emotions cingulate gyrus – – hippocampus – amygdala
103
higher brain functions
sleep, memory, cognition, emotion, sensation, motor control, and language
104
electroencephalogram
(EEG) –monitors surface electrical activity of the brain waves
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brain waves
rhythmic voltage changes resulting from synchronized postsynaptic potentials at the superficial layer of the cerebral cortex
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alpha waves 8 –13 Hz
awake and resting with eyes closed and mind wandering | –suppressed when eyes open or performing a mental task
107
beta waves 14 –30 Hz
–eyes open and performing mental tasks | –accentuated during mental activity and sensory stimulation
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theta waves 4 –7 Hz
–drowsy or sleeping adults | –if awake and under emotional stress
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delta waves high amplitude, less than 3.5 Hz
–deep sleep in adults
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sleep occurs in cycles called
circadian rhythms | –events that reoccur at intervals of about 24 hours
111
sleep
temporary state of unconsciousness from which one can awaken when stimulated
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sleep paralysis
inhibition of muscular activity
113
coma or hibernation
states of prolonged unconsciousness where individuals cannot be aroused from those states by sensory stimulation
114
sleep spindles
high spikes resulting from interactions between neurons | of the thalamus and cerebral cortex
115
slow-wave-sleep(SWS)
EEG dominated by low-frequency, high amplitude delta waves
116
rhythm of sleep
controlled by a complex interaction between the cerebral cortex, thalamus, hypothalamus, and reticular formation HYPOTHALAMUS
117
suprachiasmatic nucleus (SCN)
In hypothalamus another important control center for sleep
118
Stage 1
feel drowsy, close our eyes, begin to relax
119
Stage 2
pass into light sleep
120
Stage 3
moderate to deep sleep
121
Stage 4
called slow-wave-sleep(SWS) –EEG dominated by low-frequency, high amplitude delta waves
122
cognition
the range of mental processes by which we acquire and use knowledge
123
association areas of cerebral cortex
constitutes about 75% of all brain tissue
124
parietal lobe association area
perceiving stimuli
125
temporal lobe association area
identifying stimuli
126
frontal lobe association area
planning our responses and personality
127
learning
acquiring new information
128
memory
information storage and retrieval
129
forgetting
eliminating trivial information; as important as remembering
130
amnesia
defects in declarative memory –inability to describe past events
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– anterograde amnesia
unable to store new information
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– retrograde amnesia
– cannot recall things they knew before the injury
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procedural memory
ability to tie your shoes
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hippocampus
important memory-forming center | Does not store memories
135
amygdala
emotional memory
136
prefrontal cortex
seat of judgment, intent, and control over expression of emotions
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primary sensory cortex
sites where sensory input is first received and one becomes conscious of the stimulus
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special senses
limited to the head and employ relatively complex sense organs
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special senses 5
``` vision •hearing •equilibrium •taste smell ```
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The General Senses
general (somesthetic, somatosensory, or somatic) senses –distributed over the entire body and employ relatively simple receptors
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sensory homunculus
diagram of the primary somesthetic cortex which resembles an upside-down sensory map of the contralateral side of the body •shows receptors in the lower limbs projecting to the superior and medial parts of the gyrus
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somatotopy
the point-to-point correspondence between an area of the body and an area of the CNS
143
Motor Control
the intention to contract a muscle begins in motor association (premotor) area of frontal lobes
144
upper motor neurons
pyramidal cells of the precentral gyrus are called upper motor neurons
145
lower motor neurons
in the brainstem or spinal cord, the fibers from upper motor neurons synapse with lower motor neurons whose axons innervate the skeletal muscles
146
Highly Important in motor control
basal nuclei | cerebellum
147
Language
language include several abilities: reading, writing, speaking, and understanding words assigned to different regions of the cerebral cortex
148
Wernicke area
Understanding and planning Plan sent to Broca for execution permits recognition of spoken and written language and creates plan of speech
149
Broca area
Plan for the muscles movement generates motor program for the muscles of the larynx, tongue, cheeks and lips
150
aphasia
any language deficit from lesions in same hemisphere (usually left) containing the Wernicke and Broca areas
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anomic aphasia
can speak normally and understand speech, but cannot identify written words or pictures
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cerebral lateralization
the difference in the structure and function of the cerebral hemispheres
153
left hemisphere
categorical hemisphere –specialized for spoken and written language –sequential and analytical reasoning (math and science) –breaks information into fragments and analyzes it in a linear way
154
right hemisphere
representational hemisphere –perceives information in a more integrated holistic way –seat of imagination and insight –musical and artistic skill –perception of patterns and spatial relationships –comparison of sights, sounds, smells, and taste
155
Cranial Nerves
–most of the input and output travels by way of the spinal cord –12 pairs of cranial nerves arise from the base of the brain –exit the cranium through foramina –lead to muscles and sense organs located mainly in the head and neck
156
Cranial Nerve Pathways
most cranial nerves carry fibers between brainstem and ipsilateral receptors and effectors
157
most motor fibers of the cranial nerves begin
in nuclei of brainstem and lead to glands and muscles
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sensory fibers begin in receptors located mainly in
head and neck and lead mainly to the brainstem
159
Cranial Nerve Classification
some cranial nerves are classified as motor, some sensory, others mixed
160
sensory
(I, II, and VIII)
161
motor
(III, IV, VI, XI, and XII) | •stimulate muscle but also contain fibers of proprioception
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mixed
(V, VII, IX, X) •sensory functions may be quite unrelated to their motor function –facial nerve (VII) has sensory role in taste and motor role in facial expression
163
I
``` Olfactory Nerve sense of smell Sensory Cribiform foramina Olfactory mucosa to olfactory bulbs to inferior medial of temporal lobe Ipsilateral ```
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II
``` Optic Nerve provides vision Sensory Optic foramen Retina to thalamus and occipital lobe Hemidesicates ```
165
III
``` Oculomotor Nerve Motor Eye movements Midbrain to eye muscles and to the levator palpebrae superious (only one not innervated by facial nerve ) Superior orbital fissure Ipsilateral ```
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IV
``` Trochlear Nerve eye movement (superior oblique muscle) Motor Midbrain to superior oblique muscle of the eye Superior orbital fissure CONTRALATERAL ```
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V
``` Trigeminal Nerve - mixed •largest of the cranial nerves •most important sensory nerve of the face •forks into three divisions: –ophthalmic division (V1) –sensory –maxillary division (V2) –sensory –mandibular division (V3) -mixed ```
168
VI
``` Abducens Nerve Motor Pons to lateral rectus muscle Superior orbital fissure provides eye movement (lateral rectus m.) Ipsilateral ```
169
VII
``` Facial Nerve Mixed Pons to facial muscles Style mastoid foramen Ipsilateral Main nerve for facial expression Carrying taste from anterior 2/3 of tongue ```
170
VIII
``` Vestibulocochlear Nerve Sensory Ipsilateral Inner ear to pons Internal acoustic meatus hearing and equilibrium ```
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IX
Glossopharyngeal Nerve Mixed Medula to Jugular foramen swallowing, salivation, gagging, control of BP and respiration •sensations from posterior 1/3 of tongue
172
X
Vagus Nerve Mixed Attaches to medula down to large intestine Jugular foramen Most important parasympathetic •most extensive distribution of any cranial nerve Carries taste from cheeks, •major role in the control of cardiac, pulmonary, digestive, and urinary function •swallowing, speech, regulation of viscera
173
XI
``` Accessory Nerve Motor Medula to trapezius, SCM and paletioglossis Jugular foramen Ipsilateral ``` swallowing, head, neck and shoulder movement
174
XII
Hypoglossal Nerve Motor Medula to extrinsic muscles of the tongue Hypoglossal canal tongue movements for speech, food manipulation and swallowing
175
Trigeminal neuralgia
(tic douloureux) –recurring episodes of intense stabbing pain in trigeminal nerve area (near mouth or nose) –pain triggered by touch, drinking, washing face
176
Bell’s palsy
degenerative disorder of facial nerve causes paralysis of facial muscles on one side
177
functional magnetic resonance imaging (fMRI)
looks at increase in blood flow to an area (additional glucose is needed in active area)
178
positron emission tomography (PET) and MRIvisualize
increases in blood flow when brain areas are active –injection of radioactively labeled glucose •busy areas of brain “light up”
179
Cranial nerves Acromions Names and functions
Oh once one takes the anatomy final very good vacations are heavenly - names Some say marry money but my brother says bad business marry money - functions
180
nonfluent (Broca) aphasia
nonfluent (Broca) aphasia – lesion in Broca area – slow speech, difficulty in choosing words, using words that only approximate the correct word
181
• fluent (Wernicke) aphasia
– lesion in Wernicke area – speech normal and excessive, but uses jargon that makes little sense – cannot comprehend written and spoken words • anomic aphasia – can speak normally and understand speech, but cannot identify written words or pictures
182
Cranial V1
.
183
Cranial V2
.
184
Cranial V3
.