08.13 - Blood Flow, Ventilation-Perfusion (Leffler) - Question Flashcards Preview

Pulmonology > 08.13 - Blood Flow, Ventilation-Perfusion (Leffler) - Question > Flashcards

Flashcards in 08.13 - Blood Flow, Ventilation-Perfusion (Leffler) - Question Deck (28):
1

Ratio of change in pressure to change in blood flow in pulmonary circulation

Greater than 1:1 --> Blood flow change is more than pressure change causing it

2

Blood flow in base vs apex

Blood flow increases from apex to base of lungs

3

Vascular resistance in base vs apex of lung

Vascular resistance decreases from apex to base

4

Pressure in base vs apex of lung

Pressure increases; Pressure drop increases from apex to base

5

PA vs Pa vs Pv in top third of lung

PA>Pa>Pv

6

PA vs Pa vs Pv in middle third of lung

Pa>PA>Pv

7

PA vs Pa vs Pv in bottom third of lung

Pa>Pv>PA

8

Blood pressure in base vs apex

Blood Pressure increases from apex to base

9

Where does fluid move out of lungs?

Where pressure is highest --> Base of lungs --> Edema in CHF

10

Which part of lung becomes edematous in CHF

Base, highest pressure

11

Lung arteries and arterioles constrict in response to

Hypoxia, Hypercapnia, Acidosis

12

Effect of Hypoxia on Lung arteries and arterioles

Constrict

13

Effect of Hypercapnia on Lung arteries and arterioles

Constrict

14

Cause of chronic pulmonary hypertension

Hypoxia --> Increased Pulmonary Vascular Resistance

15

VA/Q ___ from lung apex to base

decreases

16

The greater the VA/Q, the ___ the O2, and the __ the CO2

Higher O2, Lower CO2

17

Compliance at top of lung vs bottom

Lower compliance at top --> Less change in volume for given change in pressure

18

Which part of lung has highest compliance

Bottom --> Greater change in volume for given change in pressure

19

Change in VA/Q from bottom to top of lung

Increase

20

Change in Q and VA from base to apex of lung

Both decrease, but Q decreases more rapidly

21

Which part of lung has highest partial pressure of O2

Top --> Hyperventilated --> Blood flow much lower than ventilation

22

Which part of lung has lowest partial pressure of O2

Base --> Hypoventilated

23

Which part of lung has higher partial pressure of CO2

Base

24

Hypoperfused by normally ventilated =

High PO2

25

Hypoventilated by normally perfused =

Low PO2

26

T/F: VA/Q mismatch or shunt can both increase PaCO2

False, neither

27

T/F: Hypoxemia can be caused by VA/Q mismatch

TRUE

28

T/F: Hypoxemia can be caused by Shunt

TRUE