08.18 - COPD, Emphysema (Headley) - Questions Flashcards Preview

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Flashcards in 08.18 - COPD, Emphysema (Headley) - Questions Deck (63)
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1

What FEV/FVC ratio corresponds to airway obstruction

<70%

2

What defines "irreversible" airway obstruction

Does not improve by >15% with bronchodilators

3

Immune cells distinct to COPD in contrast to asthma

CD8 T Cells; CD68+ Macrophages

4

Primary cause of COPD

Cigarrette smoke

5

FEV1 of ____ of predicted is associated with exertional dyspnea

40-60%

6

FEV1 of ____ of predicted is associated with disability

< 30%

7

FEV1 <30% of predicted is associated with

Disability

8

FEV1 < ___ = 5 year mortality 50%

FEV1 < 1 L

9

FEV1 < 1 L =

5 year mortality 50%

10

Pack years on average for COPD

20 pack years

11

At what age does COPD become symptomatic

40's

12

When does dyspnea develop

50's - 60's

13

What is required to make Dx of COPD

Spirometry: Post-bronchodilator FEV1/FVC < 70%

14

T/F: COPD can include a "reversible" component

True

15

Sputum production in COPD

Tenacious, mucoid, small quantities

16

Definition of Chronic Bronchitis

Production of sputum for 3 months in 2 consecutive years

17

Production of sputum for 3 months in 2 consecutive years

Definition of Chronic Bronchitis

18

Change in sputum color suggests

Infectious exacerbation

19

Why quantify dyspnea in COPD?

Predicts QOL and survival

20

Physical exam signs of Airflow limitation

Wheezing; Prolonged forced expiratory time

21

Physical exam signs of Hyperinflation

Barrel chest; Pursed Lip; Low diaphragm; Decr intensity of hearth and breath sounds

22

Physical exam signs of Mechanical Impairment

Accessory muscles; In-drawing of lower intercostal interspaces; Chest/abdominal wall paradoxical movements

23

For how long must hyperinflation be present to develop barrel chest

7 years

24

Heart Auscultation in COPD

Cor Pulmonale signs: S2 split, Pulmonary or Tricuspid Regurgitation Murmur

25

DLCO in COPD

Reduced in Emphysema; Normal in Chronic Bronchitis and Asthma

26

If __ are destroyed, DLCO will be low

Alveoli

27

COPD that occurs with Alpha-1 Antitrypsin is usually ___

Pan-Acinar

28

COPD that occurs with smoking (as opposed to A1A) is usually ___

Central Lobular

29

What screening do you perform with COPD develops in white patient under 45 or with strong family hx

A1A Deficiency

30

Pan-Acinar COPD occurs with

A1A Deficiency

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