Infectious Disease 8 Flashcards

1
Q

Mycobacterium marinum ( TB in water) treatment>

A

Moxifloxacin
Clarithromycin
Rifampicin

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2
Q

Lucio phenomenon caused by?

A

Mycobacterium leprae

- blue hemorrhagic lesion with necrotizing ulceration

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3
Q

What species of Aedes mosquito reduces Dengue transmission?

A

Wolbachia

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4
Q

Amphotericin B mechanism of action?

A

bind ergosterol membrane - altering integrity

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5
Q

Triazoles ( fluco/ketoconazoles) mechanism of action?

A

inhibit CYP450 - decreased ergosterol production

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6
Q

Terbinafine ( allylamines) mechanism of action?

A

Inhibit squalene epoxidase - decrease in lanosterol + ergosterol

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7
Q

Flucytosine mechanism of action?

A

Converted to 5-fluorouracil - incorporate into fungal RNA and inhibit protein synthesis/ thymidylate synthase

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