COPD clinical features Flashcards

1
Q

what is COPD

A

chronic obstructive pulmonary disease which is characterised by persistent respiratory symptoms and airflow limitation that is due to airway and or alveolar abnormalities. common, preventable and treatable. includes emphysema and chronic bronchitis (and asthma)

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2
Q

clinical features of COPD

A

cough, breathlessness, sputum, frequent chest infections, wheezing, (weight loss, fatigue, swollen ankles). can all differ in severity. get worse over time

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3
Q

what causes COPD

A

smoking, biomass fuel, air pollution, occupational exposure to dust or fumes, pre existing asthma

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4
Q

alpha 1 antitrypsin deficiency

A

rare inherited disease that presents with early onset COPD in people under age of 45. leads to alveolar damage and emphysema

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5
Q

alpha 1 antitrypsin deficiency

A

rare inherited disease that presents with early onset COPD in people under age of 45

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6
Q

examination findings for COPD

A

cyanosis, pursed lip breathing, hyperinflated chest, cachexia, use of accessory muscles, wheeze, peripheral oedema, raised Jugular venous Pressure, RR less than 25 per min

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7
Q

indications of alpha 1 antitrypsin deficiency

A

basal predominance of emphysema, young person showing signs of COPD, liver fibrosis or cirrhosis

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8
Q

examination findings for COPD

A

cyanosis, pursed lip breathing, hyperinflated chest, cachexia, use of accessory muscles, wheeze, peripheral oedema, raised JXP

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9
Q

indications of alpha 1 antitrypsin deficiency

A

basal predominance of emphysema, young person showing signs of COPD, liver fibrosis or cirrhosis

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10
Q

investigations done in hospital for COPd

A

chest x ray, blood gases, sputum culture, viral throat swab, full blood count, kidney function

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11
Q

how can spirometry help in COPD diagnosis

A

in asthma, spirometry can be normal but with COPD, spirometry will be abnormal- FEV1 80% less than predicted value or higher depending on severity

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12
Q

how are lungs affected by COPD

A

decreased ventilation due to obstruction of airflow and decreased perfusion due to emphysema so matched defect. sometimes ventilatory failure if ventilation of pCO2 is decreased- flapping tremor.

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13
Q

where does emphysema usually occur

A

in upper zone of lungs due to inhalation of smoke

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14
Q

cor pulmonale

A

condition that causes right side of the heart to fail due to increased blood pressure due to smoking or hypoxia. can cause fluid retention. caused by severe COPD

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15
Q

secondary polycythaemia

A

raised haemoglobin level which causes blood to thicken and increases risk of stroke. caused by severe COPD

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16
Q

how can some patients develop a hypoxic drive

A

severe ventilatory problems can lead to reduced sensitivity of CO2 chemoreceptors in medulla