pathology of pulmonary infection Flashcards

1
Q

lung infections may be outcome of

A

microorganism pathogenicity, capacity to resist infection and population at risk

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2
Q

examples of respiratory tract defence mechanisms

A

general immune system, respiratory tract secretions, upper respiratory tract acts as a filter

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3
Q

macrophage mucociliary escalator system involves

A

alveolar macrophages getting on to mucociliary escalator which is going out of the lung and cough reflex

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4
Q

effects that lower respiratory tract infections can have

A

cytopathic effect of viral infection, damaging epithelial cells and losing function of mucociliary escalator. chronic bronchiolitis,

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5
Q

pneumonia can be classified

A

anatomically, aetiologically, microbiologically

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6
Q

types of pneumonia

A

community acquired, hospital acquired, in immunocompromised, atypical, aspiration, recurrent

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7
Q

bronchopneumonia

A

both lungs, usually lower lobes, common in copd patients, focal problem centred on small airways,

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8
Q

lobar pneumonia

A

effects a lobe, inflammatory reaction to the infectory organism, causes consolidation

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9
Q

outcomes of pneumonia

A

resolve, pleurisy, pleural effusion, empyema, organisation (lump), lung abscess, bronchiectasis,

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10
Q

when can a lung abscess develop

A

if there is a tumour, aspiration, particular organisms eg staph aureus, metastatic in pyaemia, can be a secondary infection of necrotic lung tissue

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11
Q

bronchiectasis is

A

pathological dilation of bronchi

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12
Q

bronchiectasis is caused by

A

severe infective episodes, recurrent infections, proximal bronchial obstruction, lung parenchymal destruction

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13
Q

aspiration pneumonia can be due to

A

food into lungs-
vomiting, oesophageal lesion, obstetric anaesthesia on full stomach, neuromuscular disorders eg gag reflex loss of function, sedation

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