11. disseminierte intravasale Koagulopathie Flashcards by Ian Paglione

Q

(DIC)

Ätiologie (2)

A

Sepsis
Trauma

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Q

(DIC)

Pathophysiologie

A

Gerinnungsaktivierung
Hyperkoagulabilität
Mikrothromben
Fibrinolyse

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Q

(DIC)

Typen

A

1-4

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Q

(DIC)

Typ 1

A

DIC mit Blutung

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Q

(DIC)

Typ 2

A

DIC mit Organversagen

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Q

(DIC)

Typ 3

A

DIC mit massiver Blutung

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Q

(DIC)

Typ 4

A

asymptomatischer DIC

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Q

(DIC)

Phänotypen (3)

A

thrombotischer
fibrinolytischer
balancierter

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Q

(DIC)

thrombotischer Phänotyp: Beispiel

A

bei Sepsis

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Q

(DIC)

thrombotischer Phänotyp: Folge

A

Organversagen

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Q

(DIC)

fibrinolytischer Phänotyp: Beispiel

A

bei hämatologischen Erkrankungen

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Q

(DIC)

fibrinolytischer Phänotyp: Folge

A

Blutungen

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Q

(DIC)

balancierter Phänotyp: Beispiel

A

bei soliden Tumoren

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Q

(DIC)

balancierter Phänotyp: Folge

A

asymptomatische

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Q

(DIC)

Symptome (3)

A

Blutungen
Thrombosen
Organversagen

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Q

(DIC)

häufigste Organversagen (2)

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A

ARDS
ANV

Q

(DIC)

ARDS

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A

Acute Respiratory Distress Syndrom

Q

(DIC)

Score

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A

DIC-Score der ISTH

Q

(DIC)

ISTH

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A

International Society on Thrombosis and Haemostasis

Q

(DIC)

DIC-Score der ISTH: Parameter (4)

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A

Thrombozytenzahl
Quick-Wert
Fibrinogen
D-Dimere

Q

(DIC)

Laborbefunde (4)

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A

↓ Thrombozytenzahl
↓ Quick Wert
↓ Fibrinogen
↑ D-Dimere

Q

(DIC)

Therapieplanung

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A

supportive
kausale

Q

(DIC)

supportive Therapie

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A

Antikoagulations-
Substitutions-

Q

(DIC)

Antikoagulationstherapie: Indikation

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A

bei thrombotischem Phänotyp

(DIC) Substitutionstherapie: Indikation

bei fibrinolytischem Typ

(DIC) Therapie bei thrombotischem Typ

Antikoagulationstherapie

(DIC) Therapie bei fibrinolytischem Typ

Substitutionstherapie