7. Immunthrombozytopenie Flashcards by Ian Paglione

Q

(Thrombozytopenien)

Ätiologien (2)

A

Bildungsstörungen im Knochenmark
vermehrter peripherer Umsatz

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Q

(Thrombozytopenien)

Bildungsstörungen im Knochenmark (4)

A

kongenital
toxisch
infektiös
neoplastisch

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Q

(Thrombozytopenien)

vermehrter peripherer Umsatz

A

immunologisch

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Q

(Thrombozytopenien)

immunologische Ursache

A

ITP

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Q

(Thrombozytopenien)

ITP

A

Immunthrombozytopenie

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Q

(Thrombozytopenien)

ITP: Pathophysiologie

A

Auto-AK gegen Thrombozyten und Megakaryozyten

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Q

(Thrombozytopenien)

ITP: Ursachen (Häufigkeit)

A

80% primäre
20% sekundäre

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Q

(Thrombozytopenien)

Symptome die GEGEN ITP sprechen (5)

A

Splenomegalie
Lymphadenopathie
palpable Purpura
flächenhafte Blutungen
Gelenkblutungen

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Q

(Thrombozytopenien)

ITP: Therapie der Wahl

A

hochdosierte Glucocorticoide

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Q

(Thrombozytopenien)

Diagnostik

A

Ausschlussdiagnose

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Q

(Thrombozytopenien)

Leitsymptome (2)

A

Petechien
Blutungssymptome

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Q

(Thrombozytopenien)

Petechien: Lokalisationen (3)

A

Unterschenkel
Rücken
Schleimhäute

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Q

(Thrombozytopenien)

Blutungssymptome (3)

A

Epistaxis
Hämatome
Hypermenorrhö/Metrorrhagie

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Q

(Thrombozytopenien)

Labordiagnostik (3)

A

Blutbild
Blutausstrich
ThromboExact/Citrablut

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Q

(Thrombozytopenien)

ThromboExact/Citrablut: Zweck

A

Pseudothrombozytopenie ausschließen

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