Airway Limitation Mechanisms Flashcards
1
Q
what are the 4 most important mechanisms?
A
- loss of lung elastic recoil
- peribronchiolar fibrosis
- increased airway secretions
- airway smooth muscle
2
Q
why does peribronchiolar fibrosis occur?
A
occurs due to an imbalance between the lungs repair and defense mechanisms
3
Q
how is airway remodelling defined?
A
the persistent changes that occur within the structural components of the airways in response to inflammation
4
Q
in COPD there is increased airway smooth muscle tone which causes what?
A
hyperactivity of the bronchi and bronchoconstriction related to persistent inflammation
5
Q
what causes airway resistance?
A
airways become narrow
