Pharm Bronchodilators

Question 1

what is the main pharmacological therapy for COPD?

Answer 1

bronchodilators

Question 2

what formulations are offered in bronchodilators?

Answer 2

short and long acting

Question 3

what is the purpose of inhaled anticholinergics?

Answer 3

decrease bronchoconstriction by reducing muscle tone

Question 4

what do inhaled anticholinergics prevent?

Answer 4

they block acetylcholine from interacting with cholinergic ganglionic M1 and post ganglionic M3 receptors thereby preventing airway smooth muscle contraction and mucus gland secretion

Question 5

when should inhaled anticholinergics be used with caution?

Answer 5

in persons glaucoma or prostate symptoms

Question 6

what is the most common side effect of inhaled anticholinergics?

Answer 6

dry mouth

Question 7

what is the purpose of inhaled beta-2-adrenergic receptor agonists?

Answer 7

cause bronchodilation by acting on the beta-2-adrenergic receptors located on the smooth muscle of the airways

Question 8

what happens when beta-2-adrenergic receptors are stimulated?

Answer 8

there is an increase in the production of cyclic-AMP, which promotes smooth muscle relaxation

Question 9

what long acting beta-2-adrenergic receptor agonists are recommended as maintenence therapies for the long term prevention and reduction of symptoms?

Answer 9

salmeterol and formoterol