UCC and other Neoplasia

Question 1

What is the most common type of urinary bladder tumor in a dog?

Answer 1

UCC

Question 2

Where are UCCs most commonly located?

Answer 2

Trigone region

Question 3

Are UCCs capable of metastasis?

Answer 3

YES

Question 4

What stage do dogs usually get diagnosed with bladder tumors?

Answer 4

T2 - tumor is invading the bladder wall

Question 5

What are the risk factors for a bladder tumor?

Answer 5

Exposure to older generations flea control products
Lawn chemicals
Obesity
Cyclophosphamide exposure
Sex (female > male, neutered > intact)
Breed
Smoking in household

Question 6

What breeds are at most risk of a bladder tumor?

Answer 6

Scottish Terrier
Sheltie
Beagle

Question 7

What are the common clinical signs of bladder cancer in dogs?

Answer 7

Hematuria
Dysuria
Pollakiuria
Stranguria

Question 8

How should you collect urine? What should you never do?

Answer 8

Free catch or catheter
Avoid cystocentisis - UCC likes to see

Question 9

How should you collect urine? What should be avoided?

Answer 9

Free catch or catheter
Avoid cystocentesis - UCC likes to seed

Question 10

What other differentials should you keep in mind when thinking of UCC?

Answer 10

Other neoplasia
Chronic cystitis
Polypoid cystitis
Fibroepithelial polyps
Granulomatous cystitis
Calculi

Question 11

What test is the best to determine bladder cancer?

Answer 11

CADET BRAF urine test

Question 12

What are the indications for surgery with bladder cancer?

Answer 12

Last resort tissue diagnosis
Removal of the mass from the bladder if not affecting the trigone
Maintain or restore urine flow

Question 13

What is indicated in dogs with urethral obstruction?

Answer 13

Urethral stenting

Question 14

What are the medical therapy options?

Answer 14

Single agent COX inhibitors (Piroxicam or Deracoxib)
Chemotherapy (Mitoxantroe and Piroxicam, Cisplatin, Carboplatin)

Question 15

What is different about feline urinary bladder tumors?

Answer 15

Slowly progressing, old cats, usually have other disease processes that are treated first

Question 16

What type of renal tumors are most comon?

Answer 16

Tumors metastasizing from other locations

Question 17

Describe renal tumors in German Shepherds.

Answer 17

Dermal fibrosis and fibromas
Renal cyst adenocarcinoma
Uterine tumors

Question 18

What is the treatment for renal tumors?

Answer 18

Nephrectomy

Question 19

Are feline renal tumors metastatic?

Answer 19

Yes

Question 20

What is the most common prostate tumor?

Answer 20

Carcinoma

Question 21

Are prostate tumors in dogs androgen independent or dependent?

Answer 21

Independent

Question 22

What breeds are associated with prostate tumors?

Answer 22

Scottish Terrier
Shetland Sheepdog

Question 23

Are prostate tumors highly metastatic?

Answer 23

Yes, commonly metastasize to bones

Question 24

What are the clinical findings of a prostatic tumor?

Answer 24

Prostatomegally (without pain on palpation)
Hematuria, dysuria, stranguria, dyschezia, tenesmus, bacteriuria
Severe bone pain

Question 25

What are the diagnostic options for prostatic masses?

Answer 25

Most common: CADET BRAF Urine Test
Ejaculation
Traumatic catheterization
Prostatic massage
Prostatic wash
Ultrasound guided FNA and cytology
Surgical biopsy

Question 26

What is the preferred treatment for prostatic tumors?

Answer 26

Radiation therapy +/- chemotherapy