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APEX > IV Anesthetics > Flashcards

IV Anesthetics Flashcards

1
Q

Propofol infusion syndrome is categorized by the presence of?

A

Bradycardia & metabolic acidosis

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2
Q

What preservative is used in Diprivan?

A

Disodium edetate

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3
Q

What preservative is used in generic Propofol?

A

Sodium metabisulfite

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4
Q

What population is affected by the preservative in Propofol? What preservative?

A

May cause bronchospasm in pts with asthma
Metabisulfite

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5
Q

_____ ____mg IV can reduce itching caused by spinal opioids & cholestasis

A

Propofol 10 mg

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6
Q

Propofol ____ mg can be used to treat PONV

A

10-20

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7
Q

What enzyme converts fospropofol to Propofol?

A

Alkaline phosphatase (found in vascular endothelium)

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8
Q

What is the bolus dose of fospropofol?

A

6.5 mg/kg

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9
Q

What is the onset of fospropofol?

A

5-13 min

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10
Q

Ketamine dissociates the ____ (sensory) from the _____ (awareness)

A

Thalamus; limbic system

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11
Q

What receptors does ketamine work on?

A

NMDA
Opioid
MAO
Serotonin
NorEpi
Muscarinic
Na channels

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12
Q

What is an active metabolite if ketamine?

A

Norketamine

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13
Q

Thipoental is a thionarbiturate with a ____ molecule in the second position

A

Sulfur

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14
Q

What drugs should you avoid for acute intermittent porphyria?

A

Barbiturates
Etomidate
Ketamine
Ketorolac
Amio
CCBs
Birth control pills

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15
Q

What is the induction dose for methohexital?

A

1-1.5mg/kg

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16
Q

What barbiturate is the gold standard for electroconvulsive therapy?

A

Methohexital

17
Q

What are 2 treatments for infra-arterial injection of thiopental?

A

Local injection with phentolamine or phenoxybenzamine
Or
Sympathectomy (Stellate ganglion block or brachial plexus block)

18
Q

Precedex decreases ____, which inhibits the ____ ____ in the pons (causing sedation)

A

cAMP;
Locus coeruleus

19
Q

Dexmedetomidine provides sedation from the ____ and analgesia from the ____

A

Locus coeruleus;
Dorsal horn of spinal cord

20
Q

What is the maintenance infusion rate for dexmedetomidine?

A

0.4-0.7mcg/kg/hr

21
Q

What is the initial dose of flumazenil?

A

0.2mg

22
Q
A

B

23
Q

What drug is this

A

Fospropofol

24
Q

What drug is this

A

Ketamine

25
Q

What drug is this

A

Etomidate

26
Q

What drug is this

A

Thiopental

27
Q

What drug is this

A

Dexmedetomidine

28
Q

What drug is this

A

Midazolam

29
Q

What are 4 signs and symptoms of serotonin syndrome?

A

Hyperthermia
Mental status changes
Hyperreflexia
Seizures

30
Q
A
31
Q
A

APEX (29 decks)

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