Inhaled Anesthetics

Question 1

The pressure exerted by a vapor in equilibrium with its liquid or solid phase inside of a closed container

Answer 1

Vapor pressure

Question 2

______ occurs when vapor pressure is equal to or greater than atmospheric pressure

Answer 2

Boiling

Question 3

A _____ solute will be more soluble in a hydrophilic solvent while a ____ solute will be more soluble in a lipophilic solvent

Answer 3

Polar
Non polar

Question 4

What percentage of body weight is accounted for by the VRG?

Answer 4

10%

Question 5

What by-product of halothane metabolism has been implicated in causing halothane hepatitis?

Answer 5

Trifluoroacetic acid

Question 6

“Changes in alveolar ventilation affect the rate of rise of FA/FI” represents what effect?

Answer 6

Ventilation effect

Question 7

List 5 causes of right-to-left cardiac shunt

Answer 7

TOF
Foramen ovale
Eisenmenger’s syndrome
Tricuspid atresia
Ebstein’s anomaly

Question 8

Which VA is affected the most by a right-to-left cardiac shunt?

Answer 8

Des (lowest solubility)

Question 9

Which VA is affected the least by a right-to-left cardiac shunt?

Answer 9

Iso (greatest solubility)

Question 10

Which anesthetic agents bear the closest chemical resemblance?

Answer 10

Des & Iso

Question 11

The Meyer-Overton rule states:

Answer 11

Lipid solubility is directly proportional to potency

Question 12

The ________ states that all anesthetics share a similar MOA but each may work at a different site

Answer 12

Unitary hypothesis

Question 13

VA produce immobility in the ____ of the spinal cord

Answer 13

Ventral horn

Question 14

Which inhaled anesthetic suppresses the hypoxic ventilators response the least? (Iso, Des, Sevo)

Answer 14

Des

Question 15

Sevo at 1.5MAC increases:

Answer 15

Cerebral blood volume

Question 16

Answer 16

Sevo

Question 17

Answer 17

Desflurane

Question 18

Answer 18

Isoflurane

Question 19

Answer 19

Halothane

Question 20

VA relaxation of which muscles contributes to upper airway obstruction?

Answer 20

Tensor palatine muscles or genioglossus

Question 21

MEPs monitor the integrity of the ________. This is perfused by ______

Answer 21

Corticospinal tract;
Anterior spinal artery

Question 22

SSEPs monitor the integrity of the _______. This is perused by __________

Answer 22

Dorsal column;
Posterior spinal arteries

Question 23

Strength of the nerve response

Answer 23

Amplitude

Question 24

Speed of nerve conduction

Answer 24

Latency

Question 25

You should be concerned about nerve ischemia when amplitude decreases by ____ or when latency increases by ___

Answer 25

> 50%
10%

Question 26

Answer 26

nitrous oxide