Lab monitoring

Question 1

When initiating therapy with spironolactone for a patient who is also on an ACE inhibitor, you advise the patient to return to check which of the following laboratory parameters?

Answer 1

Potassium

Question 2

Which of the following is most consistent with a hemogram finding in vitamin B12 deficiency that can occasionally be found with long-term metformin use?

Answer 2

Elevated MCV, normal MCHC

Question 3

When monitoring for therapeutic effect of an antiepileptic drug, the drug level should be obtained at the medication’s:

Answer 3

Trough level.

Question 4

Which of the following medications is a common cause of druginduced thrombocytopenia?

Answer 4

Unfractionated heparin

Question 5

Hepatic enzyme monitoring is recommended with long-term use of all of the following medications except:

Answer 5

Atenolol.

Question 6

Which of the following provides the best indication of the liver’s excretion function?

Answer 6

Bilirubin

Question 7

All of the following changes in electrolytes can be seen with thiazide diuretic use except:

Answer 7

Ca+ wasting.

Question 8

After discontinuing the offending medication that causes drug-induced thrombocytopenia, the platelet count usually increases in ______ days.

Answer 8

2–7

Question 9

An example of an antiepileptic drug with a wider therapeutic index is:

Answer 9

Topiramate.

Question 10

When checking a carbamazepine level in suspected toxicity, the test should be obtained approximately ___ hours after the dose is taken.

Answer 10

6–8