14 morph Flashcards
(39 cards)
normocytic normochromic
anemia of acute blood loss
RBCs small, hyperchromic, lacking central pallor
hereditary spherocytosis (HS)
Howell-jolly bodies
in asplenia?
Heinz bodies
G6PD
=dark inclusions visible with crystal violet
bite cells
G6PD
=as Mfs remove heinz bodies
Peripheral blood: irreversibly sickled cells, reticulocytosis and target cells d/t RBC dehydration
Sicklce cell anemia
chronically dehydrated, dense, rigid RBCs
SCA end stage
microcytic, hypochromic RBCs
B-thalassemia
RBCs relesed from BM have inclusions –> extravasc hemolysis
B-thalassemia
massive erythroid hyperplasia
B-thalassemia
- Anisocytosis (variable RBC size).
- Poikilocytosis (variable shape).
- microcytosis
- Hypochromia.
- Target cells.
- Basophilic stippling.
- Fragmented RBCs
B-thalassemia
-(all except snisocytosis and pokilocytosis = minor)
Hb Barts
Infants w a-thalassemia: unpaired γ-globin chains form tetramers: 4 deletions
HbH
Adults w a-thalassemia: unpaired β-globin chains form tetramers : 3 deletions
IgG (sometimes IgA) Abs to RBCs
Warm Ab Type of immunohemolytic anemia
RBCs = spherocytes
- hereditary spherocytosis (HS)
- Warm Ab Type of immunohemolytic anemia
IgM to RBC at low temps
Cold Agglutinin type of immunohemolytic anemia
IgG autoAbs bind to the P group Ag on the RBC surface in cool, peripheral regions of the body.
Cold Hemolysin type of Immunohemolytic Anemias
Schistocytes
Microangiopathic Hemolytic Anemia d/t trauma
burr cells
Microangiopathic Hemolytic Anemia d/t trauma
helmet cells
Microangiopathic Hemolytic Anemia d/t trauma
triangle cells
Microangiopathic Hemolytic Anemia d/t trauma
abn lg erythroid precursors
megaloblastic anemia
=megaloblasts
PB: Macro-ovalocytes: large, oval RBCs*
megaloblastic anemia
PB: Hyperchromic d/t ample Hb (lack fentral pallor)
megaloblastic anemia
