Lecture 15 Flashcards
1
Q
resting membrane potential
A
-60 to -70mV
2
Q
2 cause of resting membrane potential
A
concentration gradient
selective permeability
2
Q
concentration gradient
A
Na lot out, K lot in, Cl lot out, A lot in
3
Q
selective permeability
A
Na, Cl, A low permeability
K high permeability
3
Q
Nernst equation
A
(2.3RT)/(zF)*log([out]/[in])
3
Q
why membrane potential close to equilibrium potential for K
A
b/c dominant permeability is to K
4
Q
equilibrium potential for K, Na, Cl
A
equilibrium potential for K
-90mV
equilibrium potential for Na
+70mV
equilibrium potential for Cl
-80mV
5
Q
Na K pump
A
ATP is bound
ATP phosphorylated, ADP release
carrier change conformation, lose affinity of Na, high affinity to K
bind 2K
change conformation, 2K release inside
