Human Phys 2.5 Flashcards

1
Q

What does an electrical synapse allow?

A

Current to flow from one excitable cell to the other via low resistance pathways (gap junctions)

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2
Q

Where are electrical synapses found?

A

Cardiac muscle and some types of smooth muscles

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3
Q

What is transmission of gap junctions?

A

Bidirectional

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4
Q

Is there a synaptic delay in gap junctions?

A

No

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5
Q

What is a chemical synapse?

A

A gap between the Presynaptic membrane and postsynaptic membrane called the synaptic cleft (information is transmitted between them via neurotransmitters)

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6
Q

What can the change in potential on the postsynaptic side be?

A

Excitatory (depolarized, closer to 0)

Inhibitory (hyperpolarized, further from 0)

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7
Q

What is the direction of a chemical synapse?

A

Unidirectional (from Presynaptic to postsynaptic)

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8
Q

Is there a synaptic delay in chemical synapse?

A

Yes

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9
Q

Motor end plate

A

Part of the muscle fiber in direct contact with the nerve

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10
Q

Neuromuscular junction

A

Connection between a nerve and muscle fiber

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11
Q

Neuromuscular transmission

A
  1. Nerve releases acetyl choline and it binds to a nicotinic receptor
  2. Binding opens gate and allows Na+ to go in
    (Ligand gated ion channel)
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12
Q

ACh-channel is large enough to allow passage of Na+, K+, and Ca2+, so why do more Na+ ions pass through?

A

There is a large concentration of Na+

Easier for Na+ to enter than K+ to leave because cell is negatively charged

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13
Q

End plate potential

A

Local positive potential ( responsible for generation of action potential)

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14
Q

What can the end plate potential increase resting potential by?

A

50-75 mV

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15
Q

What happens as long as acetyl choline is present?

A

It continues to stimulate the motor end plate

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16
Q

How is acetyl choline removed?

A

ACh-esterase

Spillover of ACh