Human Phys 2.9 Flashcards

(27 cards)

1
Q

What do smooth muscles lack?

A

Striations

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2
Q

Do smooth muscles have actin and myosin?

A

Yes, but they are not arranged in sarcomeres

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3
Q

Motility

A

To propel chyme down the GI tract (Phasic)

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4
Q

Tension

A

To maintain appropriate vascular diameter in blood vessels (tonic)

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5
Q

What are the types of smooth muscles?

A

Unitary/visceral/single unit

Multi unit

Combination

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6
Q

What are single unit smooth muscles linked by?

A

Gap junctions

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7
Q

What are single unit smooth muscles present in?

A

GI tract

Bladder

Uterus

Ureter

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8
Q

What are single unit smooth muscles characterized by?

A

Spontaneous pacemaker activity (slow waves) (Phasic contractions)

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9
Q

Are multi unit smooth muscles linked by gap junctions?

A

No

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10
Q

What are multiunit smooth muscles present in?

A

Iris

Ciliary muscles of the lens

Vas deferens

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11
Q

What are characteristics in multiunit smooth muscles?

A

Each muscle fiber behaves as a separate motor unit

Little or no coupling between cells

Densely innervated by the ANS

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12
Q

What type of contractions do multiunit smooth muscles do?

A

Tonic

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13
Q

What is a combination of both types of smooth muscles present in?

A

Vascular smooth muscle

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14
Q

What do smooth muscles not contain?

A

Troponin complex

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15
Q

What are dense bodies in smooth muscles?

A

Behave like Z disc in the skeletal muscles

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16
Q

Have much of there length can smooth muscles contract?

A

80% (skeletal can do 30%)

17
Q

What is the myosin ATPase activity in the smooth muscles compared to the skeletal muscles?

A

1/10 compared to 1/300 is required ti maintain the same tension

18
Q

Why is myosin cross bridge much slower in smooth muscles compared to skeletal muscles?

A

Because less energy is used

19
Q

What does smooth muscle require more time for?

A

To contract and relax (slow onset of contraction)

20
Q

What is the maximum force of contraction in smooth muscle compared to skeletal muscle?

A

Much higher (4-6 kg/cm2)

21
Q

How can smooth muscles maintain prolonged tonic contractions, for hours using minimal energy?

A

Via the latch mechanism

22
Q

Stress relaxation and reverse stress relaxation

A

Allows hollow organs to maintain constant luminal pressure despite large changes in volume

23
Q

What is poorly developed in the smooth muscle?

A

Sarcoplasmic reticulum

24
Q

What is used in smooth muscles instead of troponin?

25
What is smooth muscle cell contraction initiated by?
Extracellular calcium
26
What is the correct temporal order of events for the smooth muscle?
MLC phosphorylation Contraction MLC dephosphorylation Relaxation
27
Actin and myosin filaments in smooth muscles are structured how?
Overlap, with the actin filaments anchored at dense bodies