Human Phys 1.3 Flashcards

(39 cards)

1
Q

What is diffusion?

A

Random molecular movement (move on their own)

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2
Q

How does diffusion always occur?

A

Down a concentration gradient (downhill)

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3
Q

What is simple diffusion determined by?

A

Amount of substance available

Velocity of motion

Number of size and openings (permeability)

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4
Q

What does facilitated diffusion always require?

A

Carrier protein

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5
Q

What is always true about flow down gradients?

A

There will always be an energy gradient (supports flow) and a resistance to flow

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6
Q

Flow

A

Movement of substances from one point in the system to another

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7
Q

Why does flow occur?

A

Due to the presence of an energy gradient

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8
Q

What can determine the direction of flow?

A

More than one gradient

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9
Q

What will there always be when it comes to flow?

A

Some form of resistance

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10
Q

What is true about resistance in flow?

A

It can be varied or physiologically controlled

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11
Q

Are there multiple gradients during flow?

A

Yes (working at same time)

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12
Q

What is osmosis?

A

Flow down gradient

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13
Q

How do molecules diffuse?

A

Independently of one another

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14
Q

Does the presence of a gradient mean flow will always occur?

A

No (due to resistance)

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15
Q

Chemical gradient

A

Flow occurs from higher to lower concentration

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16
Q

Electrical gradient

A

Flow occurs based on attraction between + and - charges

17
Q

What is it called when a chemical and electrical gradient are combined?

A

Electrochemical gradient

18
Q

Pressure gradient

A

Behaves same as chemical gradient (high to low pressure)

19
Q

Mole

20
Q

Equivalent

A

Used to describe the amount of charged (ionized) solute (moles x valence)

21
Q

Osmole

A

The number of particles into which a solute dissociates in solution

22
Q

Pores

A

Always open (non gated)

23
Q

What is selectivity of a pore based on?

A

Diameter and electrical charge

24
Q

Channel

A

Closed (gated)

25
What are the types of gates that come with a channel?
Voltage gated Ligand gated Mechanically gated
26
Voltage gated
Opens based on electrical charge
27
Ligand gated
Opens due to molecule binding
28
Mechanically gated
Opens due to change in pressure
29
What limits the maximum rate of facilitated diffusion?
Saturation Speed of conformational change
30
Saturation
All carrier proteins have a limited number of binding sites (and limited number of carrier proteins) (Seats available in boat)
31
Speed of conformational change
The rate of transport can never be greater than the speed of conformational change (how fast the boat can go)
32
What are the factors that affect net diffusion?
Concentration gradient Partition coefficient Diffusion coefficient Thickness of the membrane Surface area
33
Partition coefficient
Decreases the solubility of a solute in oil relative to its solubility in water
34
Diffusion coefficient
Depends on size of molecule and viscosity of the medium
35
Thickness of membrane
The greater the distance of diffusion the lower diffusion rate
36
Surface area
The greater the surface area available the higher rate of diffusion
37
What are two factors that affect net diffusion if the solute is an electrolyte?
Potential difference Diffusion potential
38
When does a diffusion potential occur?
Only if the membrane is permeable to the electrolyte
39
When will negatively charged molecules stop entering a positively charged cell?
When equilibrium is reached between both the chemical and electrical gradient