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Virology > Viral Diseases of Dogs I (8) > Flashcards

Viral Diseases of Dogs I (8) Flashcards

1
Q

What has the most clinical importance for dog viruses?

A

canine parvovirus infection

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2
Q

What is characteristic of herpesvirus?

A

latent infection, with recrudescence and intermittent or continuous virus shedding

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3
Q

Herpesvirus is [enveloped/unenveloped]

A

enveloped

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4
Q

Herpesvirus is [stable/unstable] in environment

A

unstable - which is why it spreads by close contact

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5
Q

Is Herpesvirus species specific?

A

yes - some exceptions

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6
Q

What is the epidemiology of Herpesvirus?

A

present worldwide in domestic and wild dogs
seropositive rates of >30% are common in field dogs

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7
Q

T/F: Pups can’t be born without the development of disease of herpesvirus

A

FALSE - maternal antibodies through passive transfer to puppies doesn’t always happen

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8
Q

What kinds of infection is Herpesvirus in dogs?

A

respiratory infection - mild runny nose or cough
reproductive infection - vesicles or postures of genitalia

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9
Q

Most adult infections of Herpesvirus is [symptomatic/asymptomatic]

A

asymptomatic

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10
Q

Puppies _____ age are at the highest rate of contracting Herpesvirus

A

1-3 weeks

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11
Q

For Herpesvirus, the mortality rate is high among puppies exposed during _____ and the first week of life

A

whelping
disease progression is rapid
most puppies die within 24 to 48 hours after onset of clinical signs

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12
Q

In puppies, Herpesvirus is called

A

fading puppy syndrome - systemic disease

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13
Q

What is the preferred diagnostic tools for Herpesvirus?

A

PCR
serology + clinical sigtns
virus culture
necropsy

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14
Q

What is Canine Infectious Respiratory Disease Complex?

A

bordetella bronchiseptica
canine parainfluenza virus
canine distemper
canine infleunza
canine herpesvirus
serotype 2 of canine adenovirus

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15
Q

What is the treatment for herpesvirus for puppies?

A

heat lamp, pad
IV fluids
prognosis is poor

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16
Q

What is the prevention for herpesvirus for puppies?

A

no vaccine

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17
Q

What is pseudorabies in dogs?

A

porcine herpesvirus 1
uncommon in domestic dogs

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18
Q

What are clinical signs of pseudorabies in dogs?

A

frenzy associated with intense pruritus
paralysis of jaws and pharynx
howling
death

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19
Q

What are other characteristics of adenovirus?

A

virus resistant in environment
wife range of clinical presentations
confirmed bye virus isolation or PCR
direct contact transmission or aerosol
usually more poultry than mammals

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20
Q

For adenovirus 1, infectious canine hepatitis is rarely seen in the USA in domestic dogs, except in ______

A

shelter situations

21
Q

What is this a symptom of?

A

infectious canine hepatitis - adenovirus 1
“blue eye”

22
Q

How is infectious canine hepatitis transmitted?

A

in bodily secretions, especially urine
travels to the tonsils and regional lymph nodes where it replicates
then travels to liver where it replicates again

23
Q

What are the presenting signs of CAV2 infection?

A

respiratory: dry, hacking cough, loss of appetite
can get this in crowded conditions

24
Q

What is the treatment and prevention for CAV1 and CAV2?

A

let virus run course if healthy
affected dogs should be isolated
vaccination is recommended

25
Q

Where does papillomavirus generally appear?

A

occurs principally in the mouth
offensive breath - can be very florid

26
Q

Which virus indicates a measure of immune function?

A

canine warts (papillomavirus)

27
Q

If the immune system reacts with papillomavirus, it can be what kind of infection

A

acute self-limiting

28
Q

The oral antibiotic _____ is sometimes used to treat papillomavirus

A

azithromycin

29
Q

What is the properties of papillomavirus?

A

small naked capsid, DNA genome

30
Q

How is papillomavirus acquired? Infects?

A

by close contact
infects the epithelial cells of the skin of mucus membrane

31
Q

For the papillomavirus, virus persists in the _____ layer and then produces virus in thermally differentiated _______

A

basal layer
keratinocytes

32
Q

Parvovirus replicates only in _____

A

dividing cells

33
Q

What viruses can cause abortion or fetal abnormalities (a virus we’ve talked about thus far)

A

parvovirus

34
Q

How does a dog contract parvovirus?

A

transmission by contact or
fomites

35
Q

Canine parvovirus is an example of antigenic [shift/drift]

A

drift

36
Q

What is the name for canine parvovirus?

A

CPV-2b

37
Q

Parvovirus is primarily transmitted by ______ route

A

fecal-oral

38
Q

In parvovirus, the virus is [stable/unstable] in the environment

A

stable (that’s why it lives in the ground so long)

39
Q

Where is parvovirus derived?

A

came from cats - usually stays 2a in cats

40
Q

What is the pathogenesis for parvovirus?

A

initial replication in tonsils in lymph nodes
disseminated in blood (viremia)
attacks crypt cells, leads to loss of epithelium in small intestine

41
Q

Why is parvovirus so contagious?

A

infects all ages
puppies between weening and 6 months of age most susceptible

42
Q

Parvovirus presents primarily as a(n) _______ disease

A

acute enteric disease

43
Q

Which type of vaccine is parvovirus?

A

modified live vaccine (attenuated)

44
Q

Are there parvovirus treatments?

A

not tamiflu
interferon omega
hyperimmune serum - though not widely available

45
Q

What are characteristics of coronavirus and torovirus in dogs?

A

virus unstable in environment
many serotypes
transmission by aerosol, direct contact, fomites, and common vehicl

46
Q

What is the pathogenesis for canine coronavirus?

A

confined in intestines
upper 2/3rds of small intestine
confined in intestines

47
Q

How is canine coronavirus transmissited?

A

fecal-oral route, through contaminated fomites
crowding and unsanitary conditions

48
Q

Which is characteristic of loose stool and a fetid odor and orange tint?

A

canine coronavirus

Virology (16 decks)

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