8.3 Using Genome Projects Flashcards
What is the genome?
The complete set of genetic information contained in the cells of an organism
What is genome sequencing?
Identifying the DNA base sequence and therefore the amino acid sequence of an individual
What is the proteome?
The complete set of proteins that can be produced by a cell
Can the genome be directly translated into the proteome?
Only in simple organisms
Complex organisms have non-coding DNA and regulatory genes
Give an application of sequencing the proteome in simple organisms.
Identifying potential antigens for use in vaccine production
Give some applications of genome sequencing.
Comparing genomes between species to determine evolutionary relationships
Genetic matching
Personalised medicine
Synthetic biology
How have sequencing methods changed over time?
Used to be a manual process, now automated
A reaction mixture is created and the base sequence is read by a machine