8.3 Using Genome Projects Flashcards

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1
Q

What is the genome?

A

The complete set of genetic information contained in the cells of an organism

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2
Q

What is genome sequencing?

A

Identifying the DNA base sequence and therefore the amino acid sequence of an individual

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3
Q

What is the proteome?

A

The complete set of proteins that can be produced by a cell

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4
Q

Can the genome be directly translated into the proteome?

A

Only in simple organisms
Complex organisms have non-coding DNA and regulatory genes

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5
Q

Give an application of sequencing the proteome in simple organisms.

A

Identifying potential antigens for use in vaccine production

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6
Q

Give some applications of genome sequencing.

A

Comparing genomes between species to determine evolutionary relationships
Genetic matching
Personalised medicine
Synthetic biology

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7
Q

How have sequencing methods changed over time?

A

Used to be a manual process, now automated
A reaction mixture is created and the base sequence is read by a machine

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